Volume 3 JULY 1947 Number 2NATHAN GOLDBLATT MEMORIAL HOSPITALThe continuation of the University ofChicago's outstanding position in thefield of medical research and educationis assured by the recent announcementof three new projects being developedon the campus. The first of these is a building program which will add threehospital units to the Medical School.The two other interrelated projects arethe establishment of the University ofChicago Cancer Research Foundationto provide funds for cancer research facilities and the reconstitution of theCommittee on Cancer of the Universityof Chicago to co-ordinate cancer research in the various departments.(Continued on page 2)2 MEDICAL ALUMNI BULLETINNathan Goldblatt MemorialHosp ita 1-(Continued from page 1)THE BUILDING PROGRAMThe long-awaited construction ofadditional hospital units is to becomea reality this fall when ground will bebroken for two of the three new buildings for which funds are now available.These units, already tentatively floorplanned, will be integrated into thepresent hospital plan.The Nathan Goldblatt wing, illustrated in the architect's drawing onpage 1, will be devoted to the treatment of cancer and other neoplasticdiseases. As an eastward extension ofthe Billings front corridor, this unit'sfloor space is tentatively assigned asfollows: basement, photographic laboratories; first floor, seminar and conference rooms; second floor, surgeryand dermatology clinics; third andfourth floors, wards; fifth floor, X-ray;sixth floor, operating-rooms and laboratories; and seventh floor, laboratories.Running westward to Drexel Boulevard from the Billings front corridorwill be the Hicl.s memorial wing. Itsfloor plan includes emergency admission facilities and social service officeson the first floor, with medical andorthopedic clinics on the second floor.The third, fourth, and fifth floors willbe wards; the sixth floor will containlaboratories; and the seventh floor willhouse interns and residents.The third new building, runningnorth along Drexel from the Hickswing, will be the Gilman-Smith Hospital for communicable diseases. Itsfirst three floors will consist of wardsfor acute contagious diseases; thefourth and fifth floors will be for respiratory diseases and for tuberculosis, respectively; and the sixth floor will belaboratories.A total of about 180 beds, mainly inone- and two-bed rooms, and manylaboratories will be added to the hospital by the three buildings.In addition to these major buildings,a number of other units are planned.North of Billings a building for handling radioactive materials will be constructed. A new cafeteria will extendfrom the basement into the centralcourt of the hospital. A tunnel willconnect Billings and Lying-In. Oneimportant addition to the hospital facilities has already been accomplishedas a solution of the urgent problem ofhousing for nurses. The University recently purchased the Midway-Wood- lawn Apartments at Sixty-first andWoodlawn, which is being convertedinto residences for nursing and otherhospital personnel.CANCER PROGRAMThe University of Chicago has fromthe very first been interested in theproblem of cancer. Dr. H. G. Wells,for many years the chairman of theDepartment of Pathology, was a distinguished authority on the pathology,incidence, and geographical distribution of cancer. Here Dr. Maude Slyedid her pioneer work on the heredityof cancer in mice. Dr. Phemister hasbeen a leading authority on the pathology of bone tumors, and he andDr. Brunschwig have contributed muchtoward enlarging the scope of operative surgery in dealing with abdominaland esophageal cancer. Dr. Hugginshas done brilliant work on the importance of hormones as factors in thegrowth of prostatic cancer. In everydepartment of the biological sciencesand in the physical sciences work isnow going on that is either directly orindirectly related to the problem ofcancer.The University is now taking stepsto intensify its efforts in this field. Thenew Neoplastic Disease Hospital (theNathan Goldblatt Memorial Hospital)will soon be under construction, thanksto the generous gift of $1,000,000 fromthe Goldblatt Brothers Foundation.This will provide more beds for the observation and treatment of cancer patients, more laboratory space for cancerresearch, and enlarged facilities forradiotherapy and the out-patient careof cancer patients.The University of Chicago Committee on Cancer has been reconstitutedto provide more effective co-operationand co-ordination of efforts in this fieldamong the various departments in thedivisions of the biological and the physical sciences and with the Institutesfor Nuclear Studies. The Institute forRadiobiology and Biophysics will devote a considerable part of its effortsto the study of cancer and is co-operating with the clinical departments andthe Argonne National Laboratory of theAtomic Energy Commission in thiswork.Members of the Committee onCancer are: CHARLES B. HUGGINS, professor of surgery, Chairman; ALBERTL. LEHNINGER, assistant professor ofbiochemistry; ARTHUR C. BACH MEYER,director of the University Clinics andassociate dean of the Division of the Biological Sciences; E. S. GUZMANBARRON, associate professor of biochemistry; AUSTIN M. BRUES, associateprofessor of medicine and instructorin radiobiology and biophysics; LowELL T. COGGESHALL, professor andchairman of the Department of Medicine; M. EDWARD DAns, professor ofobstetrics and gynecology; LESTER R.DRAGSTEDT, professor of surgery; EARLA. EVANS, JR., professor and chairmanof the Department of Biochemistry;J AMES FRANCK, professor of' physicalchemistry; EUGENE M. K. GElLING,Frank P. Hixon Distinguished ServiceProfessor and chairman of the Department of Pharmacology; ANNAHAMANN, assistant professor of roentgenology; R. WENDELL HARRISON, professor of bacteriology and dean of theDivision of Biological Sciences; PAULC. HODGES, professor of roentgenology;JOHN O. HUTCHENS, director of theToxicity Laboratory and associate professor and chairman of the Departmentof Physiology; MORRIS S. KHARASCH,Carl William Eisendrath Professor ofChemistry; CARL R. MOORE, professorand chairman of the Department ofZoology; PAUL E. STEINER, associateprofessor of pathology; HAROLD C.UREY, Distinguished Service Professorof Chemistry; and RAYMOND E. ZIRKLE,professor of botany and director of theInstitute of Radiobiology and Biophysics.To implement this expanded program of cancer research, there hasbeen formed the University of ChicagoCancer Research Foundation, anindependent corporation under the leadership of Mr. Maurice Goldblatt, whosesole objective is to support cancer research at the University. It will concentrate on providing increased facilities, laboratories, and buildings for theuse of our scientists. The Foundationplans to provide a laboratory buildingfor nucleonic medicine in which radioactive isotopes can be stored, processed, and used experimentally in thestudy and treatment of cancer as wellas to equip the laboratories and theradiology clinic in the Neoplastic Disease Hospital. The board of trusteesof the Foundation is composed of out·standing leaders of the Chicago com·munity: Graham Aldis, Leigh BlockEdward E. Brown, Britton I. BuddHenry Crown, Robert M. CunninghamThomas B. Freeman, Charles F. GloreMaurice Coldblatt, President, MrsNathan Goldblatt, John R. HurleyJohn S. Knight, Frank McNair, Lawrenee F. Stern, Herman Waldeck, ancEdward F. Wilson.MEDICAL ALUMNI BULLETIN 3SMYTH CALLADINE3Jn jflrmoriamDr. Cornelius A. Hospers, M.D. '32; Ph.D. '32, died in his Chicago homeof coronary thrombosis on February 20, 1947, at the age of forty-two. He wasassistant in pathology at the University of Chicago from 1929 to 1932 andintern in surgery for a year beginning July 1, 1933. Dr. Hospers then becamepathologist of several Chicago hospitals, including among others the Englewood, the Holy Cross, and the South Chicago hospitals. During the war heserved as lieutenant colonel and established several European base hospitals.At the time of his death he was pathologist of the Holy Cross Hospital.Dr. Hospers leaves his widow, Lois Ann; a daughter, Jolly Ann; a son,Cornelius J.; his father, Dr. John H., a dentist; his mother, Rosa; and twosisters, Mrs. Helen Yntema and Mrs. Ruth Bohart.Dr. Joseph Norman Smyth, forty-one, a member of our Student HealthDepartment, died in his home on February 23, 1947, of carcinoma of thecolon. He was a graduate of Loyola University School of Medicine, Chicago,in 1933. Dr. Smyth was the son of the late Dr. Joseph P. Smyth and a brotherof Homer and Harlow Smyth. Surviving are his widow, Marian; his mother,Irene; and his three sons, Joseph, Geoffrey, and Thomas.Dr. Thomas Matthew Calladine, twenty-nine, of Woodstock, Illinois, diedin Billings Hospital on February 27, 1947, of testicular embryonal carcinoma.After his graduation from the University of Rochester Medical School in 1943,he was an intern at the University of Chicago Clinics. Dr. Calla dine spenttwenty-seven months as a lieutenant in the Navy and saw service in theChina-Burma-India theater. Following an operation at a China base inJanuary, 1946, he was returned as a patient to hospitals in Bethesda, Maryland, and Great Lakes, Illinois. Dr. Canadine is survived by his wife, RuthArlene of Woodstock, Illinois; and his mother, Mrs. Thomas M. Calla dineof Rochester, New York.RESIDENT STAFF NEWSLt. Hugh E. Stephenson, Jr., writes fromthe Station Hospital, Fort Baker, San Francisco, that he has traveled 15,000 milesaround the U.S. since completing his internship here last year. He is now chiefof the surgical service in his present location. He also reads all the X-ray films.Dr. Stephenson has encountered manyfonner Billings people including WilliamWicks at Beaumont General in El Paso,Lynn Hallinger, Joe Larner, Talso, Burns,Choy, Giovachinni, Pope, and others inSan Antonio. Duke Choy has recently hada daughter and is being stationed inHawaii.Dr. Thomas S. Saunders, resident in:lennatology, '33-'34, has practiced der:natology in Portland, Oregon, for the last.en years. He is assistant clinical professor)f dermatology and syphilology at the University of Oregon Medical School. He alsoierved as secretary of the Oregon StateMedical Society for the last three years.Lt. (jg) Jay Bartlett, former surgical assistant resident, is still located at theNaval Hospital in San Diego, where heis doing neurosurgery.Dr. George E. Poucher, resident in psychiatry, '40-'41, is now engaged in privatepractice in psychiatry at 1414 Clark Building, Pittsburgh, Pennsylvania.Dr. Leffie Carlton, former surgical assistant resident, is in practice with hisuncle in Tampa, Florida.Dr. Irvin B. Gardner has opened hisoffice at 411 Primrose Road, Burlingame,California, after four years in the ArmyMedical Corps.Dr. 1. Antonio Berumen of MexicoCity and Dr. Reynaldo A. MilIa of ElSalvador are now assistant residents inanesthesiology at the University of Chicago.Dr. Walter J. Aagesen was back in practice in Anderson, Indiana, for one year onMarch first, after a five-year stretch inthe Army. Dr. Louis Rubin, '43, has returned fromArmy service and is now assistant residentin Dermatology.Dr. Paul W. Schafer is now assistantprofessor of surgery at the University ofKansas Medical School, Bell MemorialHospital, Twenty-ninth and Rainbow,Kansas City, Kansas, and consultant inthoracic surgery at the Veterans Hospital,Excelsior Springs, Missouri.John J. Fahey, a former resident in orthopedics and now a member of the orthopedic staff of the University of Illinoisand attending surgeon at St. Francis Hospital, Evanston, and Michael A. Di Cosolawere awarded the gold medal for originality of presentation and research at theannual meeting of the American Academyof Orthopedic Surgeons. Their scientificexhibit was on "Experimental Dislocationof the Shoulder."Dr. Samuel T. Thierstein, resident inobstetrics and gynecology, '42-'43, became associated with the Olney Clinic inLincoln, Nebraska, last summer afterseventeen months in the Pacific.Lt. Peter Talso visited the Clinics inDecember. At that time he was stationedin the Research Laboratory at Fort Knox,Kentucky, and his family was locatedthere also.Dr. Charles E. McLennan, intern inobstetrics, '35, will become professor andexecutive head of the department of obstetrics and gynecology at Stanford University School of Medicine on August l.Dr. Henry N. Harkins, associate professor of surgery, Johns Hopkins University School of Medicine and Johns Hopkins Hospital, has resigned to become, onJuly 1, professor of surgery and executiveofficer of the department of surgery atthe new medical school of the Universityof Washington, Seattle. He was a recentClinics visitor. Dr. Harkins is a formersurgical resident and instructor of surgeryat this institution.Dr. John S. Howe, intern in surgeryand gynecology, '32-'34, resigned as professor of pathology at the Medical Collegeof Virginia last September in order toaccept an appointment as pathologist anddirector of laboratories at the MethodistHospital, Brooklyn, New York.Dr. Paul Guerin, who is now in theArmy, was a Clinics visitor early in April.He is stationed at Valley Forge Hospital,Phoenixville, Pennsylvania, on an orthopedic service.Lt. George McMurtrey, a member ofthe air-borne paratroopers, visited theClinics April 2 on his way to Atlanta. Hehad just returned from nearly a year inGermany, where he was stationed in theMunich-Frankfurt area.. Dr. Andrew Brislen, '34, and Dr.Myron Hipskind are sharing an office inChicago and are both on the staff of theWoodlawn Hospital.(Continued on page 5)4 MEDICAL ALUMNI BULLETINSCI E'N T I F I C SECTIONNitrogen Mustard Therapy ofNeoplastic Diseases and AlliedDisorders of the HemopoieticSystemLEON O. JACOBSON ANDCHARLES L. SPURRMore than seventy patients withneoplastic and allied disorders of thehemopoietic system have been treatedduring the last four years by the intravenous administration of methyl-bis(B-chloroethyl) amine hydrochloride.The diseases treated with this nitrogenmustard include Hodgkin's disease, lymphosarcoma, multiple myeloma, acuteand chronic lymphatic leucemia, acuteand chronic myelogenous leucemia,and polycythemia rubra vera. Thedosage of the drug used in these caseswas 0.1 mg. per kilogram of bodyweight given in courses of one to sevendaily injections. Usually, however, acourse of treatment is confined to fourdaily injections. Although signs andsymptoms of drug toxicity occur, theyare not serious. Nausea and vomitingalmost invariably follow within threeto four hours after an injection of thedrug but can usually be minimized byadequate barbiturate sedation. Thrombophlebitis is avoided by adequate dilution of the drug. Leucopenia andthrombocytopenia of varying severityfollow a course of treatment withintwo to three weeks. No serious hemorrhagic complications have occurred,nor has secondary infection been aserious problem.Patients have been observed afterSingle or repeated courses of nitrogenmustard from two to forty-eightmonths. Clinical remissions of fromzero to twenty-four months have beenproduced with a single course of treatment. Whereas the course of acuteleucemia and multiple myeloma areunaffected by this drug, Significantclinical remissions have been repeatedly produced in Hodgkin's disease, lymphosarcoma, chronic lymphatic leucernia, chronic myelogenous leucemia,and polycythemia rubra vera. Of thesediseases, the most encouraging resultshave been seen in Hodgkin's disease.The common symptoms of fever, pruritus, and malaise are frequently relieved within a period of a few daysafter the initiation of treatment. Lym- phadenopathy, splenomegaly, and hepatomegaly usually regress more slowly but in favorable cases have returnedto normal in three weeks or less. Ofmore than forty patients with Hodgkin's disease who have come under ourcare, fourteen had previously beentreated extensively with X-ray therapywith brief and unsatisfactory remissions. Seven of these cases continue torespond well to nitrogen mustardtherapy. Two of these fourteen casesfailed to show a satisfactory remission,and in five a single remission of fromthree to 'ten months was produced,death following.The combination of local X-ray therapy and systemic treatment with thenitrogen mustards has already shownpromise in the treatment of certain ofthese diseases. No clear-cut advantagehas been noted in combining nitrogenmustard therapy with urethane orradiophosphorus. The search for chemotherapeutic substances which will permanently control the course of thediseases discussed above must go on.It is obvious that this nitrogen mustardis not the answer. However, it offershope that other chemotherapeuticagents may be found which will moreeffectively control or cure neoplasticdiseases.Studies of the Bacterial Floraof the Normal and Pathological Vagina and Uterus(AN ABSTRACT)K, EILEEN HITE ANDH, CLOSE HESSELTINEDepartment of Bacteriology and Parasitology and the Department ofObstetrics and GynecologyNumerous bacteria have been incriminated as the cause of puerperalinfection, but the etiological role ofmany is doubtful, since the same typeshave been isolated from the normalgenital tract and since the results ofdifferent investigators are variable,Consequently, the first stage of our investigation of puerperal infections hasbeen to survey the bacterial flora ofthe genital tract. A total of 250 cultures has been made of material fromthe vagina of 60 normal prenatal and94 pathological (73 trichomoniasis and 21 other vaginitis) patients and theuterine cavity of 50 afebrile puerperaeand 45 postabortal and febrile (chieflyendometritis) patients. The flora of thevagina of the normal and mixed vaginitis groups were remarkably similar.The incidence of aciduric rods, (Doderlein) , Staph. albus, diphtheroid rods,and fungi was high, whereas other organisms were infrequently encountered. Cultures from the trichomoniasisand postpartum (both normal and pathological) patients differed from theabove but were very ,similar �o eachother. Aerobic staphylococci, nonhcmolytic (both green-producing and indifferent) streptococci, anaerobic streptococci, and micrococci as well asanaerobic nonsporulating rods, such asBacterium necrophorum and B. melaninogenicllm, were frequently present.Diphtheroid rods were not more frequent than in cultures from the normalvagina. A study of the aerobic streptococci showed that they belong to several groups (Sherman) including thepyogenic, the viridans, and the enterococcus groups, although some couldnot be classified, Of these oiganisms,the enterococci were found to be resistant to penicillin.These results imply that the development of puerperal infection may attimes depend upon infection with particularly virulent strains, the synergistic action of mixed bacteria and/oralterations in host resistance ratherthan upon infection with a specific bacterium. Furthermore, the postpartumuterus is incriminated as a portal ofentry for organisms, such as the streptococci. Additional work is in' progress,Pathology Group StudiesProtein ProblemsThe problems of protein and aminoacid nutrition as well as certain aspectsof amino acid metabolism are heing investigated by a group of workers in theDepartment of Pathology. The projectis under the direction of Dr. Paul R.Cannon, professor and chairman of thedepartment. Amollg those partidpatingin the study at the present time are Dr.E. M. Humphreys, Dr. Earl P. Benditt,Robert VV. Wissler, C. Harold Steffee,Robert L. Woolridge, Dr. Robert Stepto, Lawrence Frazier, Olaf K, Skinsncs,Dr. :-'-1. Azirvadham, Dr. Erling Strux-MEDICAL ALUMNI BULLETIN 5ess, Donald Rowley, Norman Jenings, Dr. Matthew Kobak, Dr. Johnobin, and Dr. Murray Dworetsky.From the beginning of the study in:}41 the pathologic aspects of proteineficiency have been explored. Thisabject has assumed greater impormoe due to the increase in world-widendernutrition. Furthermore, clinicianss well as pathologists are becominglore aware of the large tissue-proteinisses which accompany many diseases.Much of the early work of the group'as concerned with the effect of proein depletion upon antibody producon. It was observed that rabbits andits fed low protein rations showed areatly diminished capacity to formntibodies in response to several typesf antigens. This diminished antibody�sponse has been found to be an imortant factor in the increased morrlity of protein-deficient rabbits andats following induced acute andhronic infections. Even the fowl,-hich is normally very resistant to theneumococcus, dies of septicemia whenifection follows protein depletion.Other experiments have demon:rated that protein-starved animalssquire extended chemotherapy (peneillin) 'compared to their controls toasure recovery from a pneumococcalifection, Apparently this is due to theecreased capacity of depleted tissues) aid the chemotherapeutic agent.'urthermore, only a low humoral an.body level is developed by such anirals during infection.Another phase of the study has beenre evaluation of the nutritive poten.alities of various proteins. During the/ar a rapid rat-repletion method waseveloped by the group to measureae fabrication of several protein comorients of the body in response to theeeding of test materials. At the reuest of the Quartermaster Corps thisiethod was utilized to assay many ofre Army emergency rations and inredients and the effects of processingnd storage upon them. Blood substi.ites, protein hydrolysates, and reliefations have been similarly evaluated..specially important was the demontration that suitable amino acid or prosin supplementation could <;10 much) improve the protein quality of theseubstances,More recently the attentions of theroup have been focused upon the£fects of single amino acid deficienies. In these experiments the dietaryitrogen is furnished by sixteen puried amino acids which are incorporated1 rations adequate in other food mate- rials. The removal of anyone of thenine indispensable amino acids (excluding arginine) leads to a promptrejection of the ration by the test animal. This is accompanied by a markedloss of weight and blood proteins.Further experiments are under way toelucidate the mechanism underlyingthis dramatic effect and to explore itspossible relationship to the negativenitrogen balance which follows burns,fractures, and other forms of tissue injury.Other experiments nearing completion have utilized the protein-deficientrat to establish the minimal essentialamino acid needs of the animal fortissue synthesis. Similarly the quantitative requirements of each essentialamino acid for the maintenance of nitrogen equilibrium have been determined. The results of these experiments indicate 'that amino acid requirements for adequate tissue synthesis inthe presence of protein deficiency arenot only greater than those for maintenance but also require the indispensable amino acids in different proportions.Among the other problems being investigated by various members of thegroup are (1) the relationships between caloric and protein requirements,(2) the relative capacities of differenttissues to fabricate protein under varying circumstances, (3) the influence ofvitamin deficiencies upon protein synthesis, (4) the effects of protein deficiency upon the bone marrow andthe leucocyte response to stimuli, (5)the relationship between endocrineimbalance and protein metabolism, (6)the effects of protein depletion onwound healing, and (7) the relativeutilizability of the d and I forms ofvarious amino acids.Awards Received for Exhibitson Gelatin Sponge for Control of Hemorrhage1. Illinois State Medical Society-Certificate of Merit, May, 19462. American Medical Association-Honorable Mention, July, 19463. Mississippi Valley Medical Society, St.Louis-Silver Medal, First Prize, Septemher, 19464. Latin-American Medical Asrociation,Mexico City-Gold Medal, SecondPrize, November, 1946The work on gelatin sponge has beendone by Dr. H. P. Jenkins in collaboration with Drs. Rohert Jampolis, EdwardSenz, Howard Owen, Rudolph Janda,James Clarke, and Peter Moulder. Thiswork is being reported in the literature in a series of articles of which five havebeen published and three are in press, Inaddition, a forty-five-minute motion picture of these studies has been completedand has been approved by the AmericanCollege of Surgeons.Resident Staff News(Continued from page 3)Lt. Douglas Morton was a Clinics visitor in May. He is now in charge of surgeryat the AAF Station Hospital at FortGeorge Wright, Spokane, Washington.The Mortons have been given excellentliving quarters on that old Army post.Dr. A. K. Rodholm has joined theMoody Clinic at Corpus Christi, Texas.Dr. Donald Ross is now a member ofthe Christie Clinic at Champaign-Urbana,Illinois.Dr. Ying Tak Chan, an early Billingsassistant resident, has arrived in this country after nine years of war experiences inChina. Shc visited the Clinics in April onher way to Washington and New York,where she will begin work on a one- totwo-year Ortho Research Foundation Foreign Visiting Fellowship for MaternalHealth Problems. She will eventually coverseveral maternity centers in this country.Dr. Chan had an eighteen-day stormycrossing on a former troopship, "The General Gordon," and they stood by for twodays in the rescue from the oil tanker thatsplit in two in the Pacific.Dr. Francis Phillips is going, on July 1,to Temple, Texas, where he has been appointed senior thoracic surgeon at a fivehundred-bed chest hospital of the VeteransAdministration.AWARDSDr, J. R. Blayney, director of theZoller Memorial Dental Clinic, has received the Ohio State Dental Society'sJohn R. Callahan Award given annually for outstanding performance indentistry.Dr, Matthew Block, '43, has beenawarded the four-hundred-dollar 1946Joseph A. Capps Prize for MedicalResearch, according to an announcement by the Institute of Medicine ofChicago. His work was on "Sequelaeof Trench Foot-Anatomic Study."RESEARCH GRANTSTO U. OF G. FACULTYThe Illinois division of the AmericanCancer Society on March 17 announcedgrants of $69,115 to twelve Chicagoansfor cancer research. In our institutiongra�ts were made as follows: Dr. E. S.Cuzman Barron, $10,000; Drs. Leon O.jacobson, Austin Brucs, Charles L. Spurr,and Mathew Bloch, $9,120; Dr. Allan T.Kenyon, $6,300; and Dr. P. E. Steiner,$3,000.6 MEDICAL ALUMNI BULLETINALUMNI NEWS'32. Alven Weil has returned from service in the medical corps and has resumedhis private practice in obstetrics andgynecology at 1030 First Central Tower,Akron, Ohio.Capt. Arthur J. Worwald, U.S.N., headof the Medical Science Section, Office ofResearch and Inventions, in the office ofthe Secretary of the Navy, Washington,D.C., was a clinics visitor in April.'34. Nathaniel Safran is now practicingradiology at Devereux Professional Building, 468 Delaware Avenue, Buffalo, NewYork.Sarah E. Branham was married to Dr.Philip S. Matthews on December 22, 1945.She is senior bacteriologist in the BiologicsControl Laboratory of the National Institute of Health, which is the Research Division of the U.S. Public Health Service.James W. Hall is in practice in internalmedicine in Traverse City, Michigan, andwrites that he is greatly enjoying theNorth Country.'36. Monroe K. Ruch is chief of thePlastic Surgery section at the McCormackGeneral Hospital in Pasadena, California.He writes that he is waiting to get "unfrozen" and start practice, probably inLos Angeles. This is the third plasticcenter in which he has worked since hisreturn from ETO, where he toured fromNormandy to Austria as chief of a maxillofacial team (4th Aux. Surg. Gp.). He hastwo boys, aged eight and eleven.'37. Leo Rangell was discharged fromthe Army in May, 1946, after serving forthree and a half years as a neuropsychiatrist with the Army Air Forces. He is nowpracticing psychiatry and neurology at405 North Bedford Drive, Beverly Hills,California.'38. Charles C. Scott is the author (withE. B. Robbins and K. K. Chen) of anarticle entitled "Comparison of Some NewAnalgesic Compounds" in Science, 104,No. 2712 (December, 1946),587--88. Thearticle deals with studies of new analgesicagents prepared by German chemists during the war. The work was done at theLilly Research Laboratories, Indianapolis.Ralph P. Christenson is in private practice, largely obstetrics and gynecology, at825 Miner Building, Eugene, Oregon.Carl D. Strouse is an instructor in medicine at the University of Southern California and doing part-time teaching ofjunior students in the wards of Los AngelesCounty Hospital.'39. Robert Warner is now at the Cincinnati Children's Hospital and ResearchFoundation after five years in the Army.Ruth I. Barnard has just completedthree years at the Menninger Foundation,where she is assistant medical director and Winter Veterans Administration Hospitaland teaches in the Menninger FoundationSchool of Psychiatry. She writes that BillLewis, '41, Byron Casey, '43, and DavidRubinfine, '44, are fellows in the Schoolof Psychiatry. Also Merton Gill, '38, ison the staff of the Menninger Foundationand a consultant at the Winter VeteransAdministration Hospital.'40. Edward Whiteley is now in Kassel,Germany, and has had his family withhim since July, 1946. In July he will return to the United States and hopes tostop in at the Clinics to say hello to allhis friends.Walter A. Stryker was professor ofpathology at the University of Michiganuntil July I, 1946. He is now in privatepractice in Detroit.'41. Clara Johns is the new health officer for Lee County Health Departmentwith headquarters at Dixon, Illinois.Owen Berg is now practicing urologyin Milwaukee and is an occasional Clinicsvisitor.Harry P. Maxwell has been practicingneurological surgery for a year and a halfnow since finishing his residency at theUniversity of Illinois under Drs. Oldberg,Bailey; and Bucy. He and Mrs. Maxwellare the proud parents of nine-month-oldtwin boys.Robert B. Sweet, who was in the medical corps of the U.S. Army Air Force andserved in England, is now at the University of Michigan Hospital in the Department of Surgery as a resident.'42. Lyndon M. Hill is now resident insurgery at Harlem Hospital, New YorkCity.Herbert D. Trace is serving a surgicalresidency at Cook County Hospital.Frank H. Belfus is at present a residentin the Department of Internal Medicineat Columbia Hospital in Milwaukee. Hehas been working in part under Dr. Elwood Mason, who was a resident and instructor in medicine here from '33 to '36.Robert R. Morris was released fromactive service as Lieutenant (M.C.),USNR, on July 8, 1946, after five monthsat the U.S. Naval Hospital in Bethesda,Maryland. Since September, 1946, he hasbeen a staff physician at St. Elizabeth'sHospital, Washington, D.C.Charles F. Williams is now a fellow ininternal medicine at the University ofMinnesota.Isadore Rossman served thirty-ninemonths in the Army, winding up as chiefof medicine at Mason General Hospital.He is now resident in medicine at Montefiore Hospital, Bronx, New York.Harlan Carey, Jr., has returned fromArmy. s��ce .and is now assistant resident Peter Beal, on a one-year leave of absence from the dermatology department,is working on "dermatrophic" viruses. Hehas a National Research Fellowship andis working in the Virus Laboratory, 1392University Avenue, Berkeley 2, California,which is connected with the CaliforniaDepartment of Public Health. -The virusresearch is carried on under the auspicesof the International Health Division ofthe Rockefeller Foundation. Dr. Beal hasrecently visited the Kahouns. Jack Kahounis still at Mare Island finishing his Navyinternship and will soon go to Pensacola,Florida, for flight-school training.'43. Colin G. Thomas was married toShirley Forbes on September 14, 1946.At present he is chief of surgery, StationHospital, Fort Monmouth, New Jersey.Robert L. Smith is now engaged in thepractice of general medicine with Leo R.Hawkes, a 1939 graduate of Rush. Hewas discharged from the Navy in May,1946.David Minard is again a civilian aftertwo years in the Navy. He saw some action at Okinawa and later spent six monthsin Tokyo Bay. He returned to the Statesin August, 1946, and took up his presentduties at the Naval Medical Research Institute, where he is assigned to the physiology facility.LaRele J. Stephens, who is back on thecampus interning in obstetrics and gynecology, spent two and a half years withthe Navy and Marine Corps in the AsiaticPacific theater and for the last. eightmonths had been running a small hospitalin a "primitive" part of Idaho.John J. Schneider is at present a research associate in the Chemistry Department of Mayo Clinics. Other U. of C. menat Mayo Clinics are Van Hunt, '44,Robert Painter, '41, and Walter Cox, '43.Charles P. McCartney is out of theArmy and is an intern at Lying-in.Ralph J. Bailey complete his appointment at the U. of C. as Kellogg Fellow inRoentgenology and has gone into practice in Chicago with Dr. William Anspach,a former member of our roentgenologyfaculty.William Webster has returned to theClinics as assistant resident in urology.G. Arthur Mulder has just been discharged from the Army after having spentseven months with the Fifth Air Force inJapan. Prior to that he had been stationedat Foster General Hospital in Jackson,Mississippi, and Kennedy General Hospital in Memphis, Tennessee. He is nowcompleting his surgical residency at Butterworth Hospital, Grand Rapids, Michigan, which he started before enteringMEDICAL ALUMNI BULLETIN 7Alfred J. D'Alessandro is at present asidcnt at the Medwood Hospital inooklyn.Robert M. McCormack is chief of handrgery at the William Beaumont Cen-11 Hospital in El Paso, Texas. He plansreturn to Strong Memorial Hospital formpletion of his training in plastic surry following separation in June.'44. Jack Farber, who recently returnedrm Japan, has become associated withrs. Wiese, Palmer, Belknap, and EmmettOntario, Oregon, where he is going into.diatrics.Capt. Frank P. Evans is chief of neuroychiatry at Fort Benning, Georgia.Hugh A. Frank is in private practice insociation with two other doctors in Elijon, California. He writes that he hasen both Drs. Trotter recently and thatey are practicing in San Diego.Virginia McDonald is now a voluntarysistant in pediatrics at the U. of C.'45. Lt. (jg) James S. Miles wrote inecemher from the Veterans Administram Hospital in San Fernando, California,at he misses a good medical library. He»uld like to trade their three- and fourLY rainstorms for a nice stiff wind on theidway.Lt. (jg) Howard Reiser is still at thewy Base, Portsmouth, New Hampshire,here he is assigned to the U.S. Navalison (Disciplinary Barracks). All theirteresting medical cases and surgicalses, except minor lacerations, etc., must, sent to the near-by Naval Hospital, sos service is hardly interesting or inrrnative.'Woodrow Kash is now junior residentmedicine at Mercy Hospital and Loyolaniversity Clinics, Chicago.Harry W. Fischer writes that he is,ing transferred to a new V.A. hospitalTomah, Wisconsin. "This hospital is toovide care for chronic psychotics. Reining an interest mainly in surgery, and.ving scrubbed twice in eight months,BULLETIN)f the Alumni AssociationIhe University of Chicago'}(f;HOOL OF MEDICINEVOL. 3 JUNE 1947 No.2W. H. T. MURRAY, EdilDrHUBERTA LIVINGSTONE, Associate EditorHENRY T. RICKETTS, Associate EditorWILLIAM B. TUCKER, CLAYTON G. LOOSLIAssistant EditorsALLAN T. KENYONFRANCIS B. GORDONHILGER P. JENKINSMembers of I". Editorial BoardMAillE ECKERT, SecretaryPrice of yearly subscription for nonmembers, $1.00;nice of single copies, 25 cents. I feel the new situation cannot be muchworse than my previous assignment ata N.P. hospital in Mendota, Wisconsin."Dr. Fischer reports that his internship insurgery at Barnes Hospital (WashingtonUniversity Medical School) in St. Louiswas excellent and that he hopes to returnthere for his resident training in generalsurgery when the Navy releases him fromhis present duties.George Krakowka has just been appointed as chief of X-ray at the VeteransHospital, Fort Harrison, Montana, to replace Dr. Alfred Benesch, '33, who hasbeen transferred to Portland to completehis boards in radiology.Loren T. DeWind is in the Army andstationed at the Veterans Hospital at Chillicothe, Ohio. As he is the only representative of the U. of C. there, he writes thatletters from classmates are most welcome.Thomas W. Anderson in January waslocated at the Naval Dispensary, Adak,Alaska, where there was no shortage ofdoctors. He has become a chess addict.Lt. (jg) C. F. Kittle, stationed at theVeterans Hospital, Los Angeles, California, spent a brief period in Chicagothis winter.Everett Van Reken is planning to goto China to take up work at a mission hospital with his wife and two children inAugust of this year.Robert Langdon is now stationed atBrown General Hospital in Dayton, Ohio,which is part of the Veterans Administration Facility.Thomas G. Harward is senior medicalofficer aboard a repair ship, the "ussHooper Island," which is stationed atTsingtao, China. He writes that HenryMcWhorter, '44, is senior medical officeron the "uss Piedmont," another repairship at Tsingtao. Ray Goodman, '44, isnow at a Marine Base Hospital in Tiensin,China, and Ed Horner, '45, was in Tsingtao in January and from there went toJapan.Warren F. Wilhelm and his familyvisited the U. of C. campus this winter.Warren is now the ward officer of theMedical Service Station Hospital, CampMcCoy, Wisconsin.'46. Clair E. Basinger finishes his internship at the Chicago Memorial Hospital in April and then is going to workfor Dr. Francis Phillips, formerly instructor in surgery at the U. of C. Clinics, inMarquette, Michigan. Dr. Phillips becamedirector and surgeon-in-chief of theMorgan Heights Sanitarium on July I,1946.John W. Cashman reports that he isenjoying his internship at the Kansas CityGeneral Hospital, after which he intendsto substitute a tour of duty with theUSPHS for his Army obligation.'47. William Beach is interning at theAlameda County Hospital and recentlypaid a visit to Dr. Whitecotton. He has alsoseen Greg Thomas, '46, Dick Taylor, '46,and Ruth Perkins, '45, who all assure himthat the internship is an excellent one. BIRTHSDr. and Mrs. W. A. Stryker, Sara Margaret,April 12, 1946Dr. and Mrs. P. L. Beal, Eric Alan, May22, 1946Dr. and Mrs. R. G. Langdon, CeceliaMarie, May 27, 1946Dr. and Mrs. J. E. Harvey, RoderickWilson, June 18, 1946Dr. and Mrs. W. B. Cox, Douglas, June27, 1946Lt. and Mrs. M. Bonfiglio, Robert, Sept.,1946Dr. and Mrs. L. D. DeWind, Sharon Ruth,Sept. 6, 1946Drs. Jonathan and Teresa (Folin) Rhoads,Philip Garrett and Charles James, Oct.7, 1946Dr. and Mrs. W. B. Tucker, Sara Waitstill, Oct. 23, 1946.Dr. and Mrs. R. L. Smith, Craig, Nov. 6,1946Dr. and Mrs. Theron Hopple, Carol Faye,Nov. 24, 1946Dr. and Mrs. Robert Warner, Robert, Dec.2, 1946Lt. and Mrs. W. F. Wilhelm, RichardWarren, Dec. 17, 1946Dr. and Mrs. Andrew Brislen, Donn Francis, Jan .. 5, 1947Dr. and Mrs. L. M. Hill, Jr., LyndonMichael, Jan. 8, 1947Dr. and Mrs. Francis Phillips, Susan Melissa, Jan. 28, 1947Dr. and Mrs. Erwin Levin, Barry, Feb.11,1947Dr. and Mrs. E. L. Borkon, daughter, Feb.14, 1947Dr. and Mrs. W. Neuman (Dr. BarbaraSpiro), Thomas George, Feb. 15, 1947Dr. and Mrs. Jay Jacoby, Jane Alice, Feb.28, 1947Dr. and Mrs. C. M. Johnson, Jr., CharlesMichael III, Feb. 28, 1947Dr. and Mrs. Howard Owen, GregoryScott, March 10, 1947Dr. and Mrs. R. F. Carlson, David John,March 12, 1947Drs. Leonard and Dorothy Ritzmann,Mary, March 21, 1947Dr.' and Mrs. Pompeyo Chavez (SabraNichols), Lucy Ellen, March 23, 1947Dr. and Mrs. Milton Landowne, Joseph,March 31, 1947Dr. and Mrs. Henry Hopple, GretchenMarie, March 24, 1947MARRIAGESDr. A. J. D'Alessandro, Lenore Holoviak,Sept. 14, 1946Dr. M. P. Woolf, Madelyne MarthaStudent, Nov. 17, 1946Dr. H. N. Gordon, Margery Elvis Lynch,March 7, 1947Dr. Richard Kershner, Marian Lumpkin,March 22, 1947Dr. W. C. Drennan, Doris Peoples, May10, 19478 MEDICAL ALUMNI BULLETINFACULTY NEWS. Dr. Jules H. Masserman, until recentlya member of our psychiatry department,and now connected with NorthwesternUniversity Medical School, has been citedby the Lasker Foundation for his outstanding research in psychiatry and its application to mental hygiene.Dr. William E. Adams was electedtreasurer of the American Association forThoracic Surgery.Dr. Arno B. Luckhardt, professor of'physiology, has been designated Distinguished Service Professor of Physiology,effective July 1, 1947.Dr. Victor E. Johnson, Ph.D. '30, M.D.'39, has been appointed to the post of director of the Mayo Foundation for MedicalEducation and Research, to succeed Dr.Donald Balfour when he becomes director emeritus in 1947. Dr. Johnson willalso be professor of physiology at the University of Minnesota. He joined the staffof the Mayo Foundation in April and willbecome director in October.Dr. N. Paul Hudson, formerly a mcmber of the U. of C. faculty and now professor and chairman of the Departmentof Bacteriology, Ohio State UniversityCollege of Medicine, has been appointeddean of the graduate school at that institution.Dr. Anton J. Carlson, president andscientific director of the Research Councilon Problems of Alcohol, took part in aconference on alcoholism as a publichealth problem on February 12, in RodgerYoung Auditorium, Los Angeles.Dr. Alfred Joseph Klein, assistant professor of medicine, has resigned. In March he went into private practice in EauClaire, Wisconsin.Dr. Huberta M. Livingstone was invited by the Mexican Society of Anesthetists to take part in the first Congressof Mexican Anesthetists which was heldin conjunction with the Seventh Congressof Surgeons and Second Congress ofBlood Transfusions in Mexico City in November. Dr. Livingstone and Dr. JoaquinCoto (voluntary assistant in anesthesiology) presented a paper on "AnestheticMortality in Intrathoracic 'Surgery."Dr. J. Robert Willson, assistant professor of obstetrics and gynecology resigned on January 1 to become head ofthe department of obstetrics and gynecology at Temple University School ofMedicine and Hospital.Dr. A. Earl Walker, professor of surgery( neurosurgery), has returned from a planetrip to South America, where he presenteda paper on "Advances in Electroencephalography" at the Second South AmericanNeurosurgical Congress held in Santiago,Chile, April 21-22. While in South America he visited hospitals in Chile; Lima,Peru; Buenos Aires; Montevideo; and Riode Janeiro.Dr. John R. Lindsay has been electedpresident of the Chicago LaryngologicalSociety.Dr. Alexander Brunschwig will be amember of a team of ten health expertssent to Austria and Hungary this summerby the Interim Commission of the UnitedNations Health Organization. The group,which leaves the states on June 26, willexplain the latest advances in medicineto Austrian and Hungarian doctors. Dr. Charles L. Dunham, assistant professor of medicine, on February 15 beganpart-time service in the U. of C. Development Office as Biological Sciences representative.Dr. Fred L. Adair, emeritus professorof obstetrics and gynecology, has returnedfrom Argentina, where, under the sponsorship of the U.S. Department of State,he served as visiting lecturer in obstetrics.He was invited by the Society of Obstetricsand Gynecology of Argentina as a specialdelegate to the sixth Argentina Congressof Obstetrics and Gynecology and alsogave lectures at the universities in BuenosAires, Cordoba, Santa Fe, and La Plata.Dr. Parker Dooley, associate professorof pediatrics, resigned his position, effective February 1. He is now vacationingat Kent, Connecticut.Dr. Seymour Gray, formerly assistantprofessor of medicine, left the Clinics onNovember 1 and now has an appointmentat Harvard Medical School as assistantprofessor of medicine and is senior associate of medicine at the Peter Bent Brigham Hospital in Boston. He is dividinghis time between duties as director ofhospital gastrointestinal clinic and research in the biophysical laboratory. Dr.Gray served as a lieutenant commanderin the Naval Reserve and was stationedat the Naval Medical Center, Bethesda,Maryland.Dr. Russell H. Morgan, associate pro·fessor of roentgenology, left the Clinic!the first of the year to be professor in thenewly created department of radiology atJohns Hopkins University. He is also radiologist-in-chief at Johns Hopkins HospitalALUMNI MEETINGThe Annual Alumni Reunion andBusiness Meeting were held in Billings,Friday evening, June 6. Dr. A. R. McIntyre, class of '31, professor of physiology and pharmacology at the University of Nebraska, spoke on "Curare."Honored guests of the evening were:Dr. Dallas B. Phemister, retiring chairman of the Department of Surgery;Dr. Lester R. Dragstedt, newly appointed chairman of the Departmentof Surgery; and Dr. Lowell T. Coggeshall, chairman of the Departmentof Medicine.The following officers were electedfor the coming year: Dr. ClaytonLoosli, president, Dr. Harry Oberhelman, vice-president; Dr. John VanProhaska, treasurer; and Dr. Charles L.Dunham, secretary. Drs. Leon Jacobson and F. Joseph Mullin were electedas members of the Council. SERVICE AWARDSCol. Paul A. Campbell, surgical interne in 1928-29, has received theLegion of Merit for his work as Director of Research, Army Air ForcesSchool of Aviation Medicine, fromMay, 1942, to October, 1945.Major Ralph W. Barris, '41, ofGrand Rapids, Michigan, has receivedthe Army Commendation Ribbon forhis meritorious service as chief of theneurology and neuro-syphilis section,Ashfort General Hospital, White Sulphur Springs, West Virginia, from September 24, 1944, to April 11, 1946.Major Oscar Bodansky, '38, of NewYork City, received the Legion of Meritfor exceptionally meritorious service aschief, biochemistry section, and technical director for medical research,medical division, OC-CWS. "His researches were indispensable in establishing the mode of action of war gases and developing methods for the treatment of casualties. His clearly demonstrated ability to inspire and lead otharesearch workers brought to him positions of major responsibility."The. Army Commendation, Ribberwas recently awarded to Major Andrew}. Brislen, '34, for the high degree of professional ability displaye<in his capacity as chief of the generamedical branch of the medical divisioiat the AAF Regional and ConvalescenHospital, Coral Gables, Florida, iJ1945.Dr. Gail M. Dack, professor of bacteriology and director of the Universitof Chicago Food Research Institutehas been awarded the Exceptional Civilian Service Decoration by the Ann:for his wartime work at Camp DeteriekFrederick, Maryland, center of the blological warfare division. Major GerAlden H. Waitt made the presentatior