Volume 3 JULY 1947 Number 2NATHAN GOLDBLATT MEMORIAL HOSPITALThe continuation of the University ofChicago's outstanding position in thefield of medical research and educationis assured by the recent announcementof three new projects being developedon the campus. The first of these is a building program which will add threehospital units to the Medical School.The two other interrelated projects arethe establishment of the University ofChicago Cancer Research Foundationto provide funds for cancer research facilities and the reconstitution of theCommittee on Cancer of the Universityof Chicago to co-ordinate cancer re­search in the various departments.(Continued on page 2)2 MEDICAL ALUMNI BULLETINNathan Goldblatt MemorialHosp ita 1-(Continued from page 1)THE BUILDING PROGRAMThe long-awaited construction ofadditional hospital units is to becomea reality this fall when ground will bebroken for two of the three new build­ings for which funds are now available.These units, already tentatively floor­planned, will be integrated into thepresent hospital plan.The Nathan Goldblatt wing, illus­trated in the architect's drawing onpage 1, will be devoted to the treat­ment of cancer and other neoplasticdiseases. As an eastward extension ofthe Billings front corridor, this unit'sfloor space is tentatively assigned asfollows: basement, photographic lab­oratories; first floor, seminar and con­ference rooms; second floor, surgeryand dermatology clinics; third andfourth floors, wards; fifth floor, X-ray;sixth floor, operating-rooms and labora­tories; and seventh floor, laboratories.Running westward to Drexel Boule­vard from the Billings front corridorwill be the Hicl.s memorial wing. Itsfloor plan includes emergency admis­sion facilities and social service officeson the first floor, with medical andorthopedic clinics on the second floor.The third, fourth, and fifth floors willbe wards; the sixth floor will containlaboratories; and the seventh floor willhouse interns and residents.The third new building, runningnorth along Drexel from the Hickswing, will be the Gilman-Smith Hos­pital for communicable diseases. Itsfirst three floors will consist of wardsfor acute contagious diseases; thefourth and fifth floors will be for respir­atory diseases and for tuberculosis, re­spectively; and the sixth floor will belaboratories.A total of about 180 beds, mainly inone- and two-bed rooms, and manylaboratories will be added to the hos­pital by the three buildings.In addition to these major buildings,a number of other units are planned.North of Billings a building for han­dling radioactive materials will be con­structed. A new cafeteria will extendfrom the basement into the centralcourt of the hospital. A tunnel willconnect Billings and Lying-In. Oneimportant addition to the hospital fa­cilities has already been accomplishedas a solution of the urgent problem ofhousing for nurses. The University re­cently purchased the Midway-Wood- lawn Apartments at Sixty-first andWoodlawn, which is being convertedinto residences for nursing and otherhospital personnel.CANCER PROGRAMThe University of Chicago has fromthe very first been interested in theproblem of cancer. Dr. H. G. Wells,for many years the chairman of theDepartment of Pathology, was a dis­tinguished authority on the pathology,incidence, and geographical distribu­tion of cancer. Here Dr. Maude Slyedid her pioneer work on the heredityof cancer in mice. Dr. Phemister hasbeen a leading authority on the pa­thology of bone tumors, and he andDr. Brunschwig have contributed muchtoward enlarging the scope of opera­tive surgery in dealing with abdominaland esophageal cancer. Dr. Hugginshas done brilliant work on the im­portance of hormones as factors in thegrowth of prostatic cancer. In everydepartment of the biological sciencesand in the physical sciences work isnow going on that is either directly orindirectly related to the problem ofcancer.The University is now taking stepsto intensify its efforts in this field. Thenew Neoplastic Disease Hospital (theNathan Goldblatt Memorial Hospital)will soon be under construction, thanksto the generous gift of $1,000,000 fromthe Goldblatt Brothers Foundation.This will provide more beds for the ob­servation and treatment of cancer pa­tients, more laboratory space for cancerresearch, and enlarged facilities forradiotherapy and the out-patient careof cancer patients.The University of Chicago Commit­tee on Cancer has been reconstitutedto provide more effective co-operationand co-ordination of efforts in this fieldamong the various departments in thedivisions of the biological and the phys­ical sciences and with the Institutesfor Nuclear Studies. The Institute forRadiobiology and Biophysics will de­vote a considerable part of its effortsto the study of cancer and is co-oper­ating with the clinical departments andthe Argonne National Laboratory of theAtomic Energy Commission in thiswork.Members of the Committee onCancer are: CHARLES B. HUGGINS, pro­fessor of surgery, Chairman; ALBERTL. LEHNINGER, assistant professor ofbiochemistry; ARTHUR C. BACH MEYER,director of the University Clinics andassociate dean of the Division of the Biological Sciences; E. S. GUZMANBARRON, associate professor of bio­chemistry; AUSTIN M. BRUES, associateprofessor of medicine and instructorin radiobiology and biophysics; Low­ELL T. COGGESHALL, professor andchairman of the Department of Med­icine; M. EDWARD DAns, professor ofobstetrics and gynecology; LESTER R.DRAGSTEDT, professor of surgery; EARLA. EVANS, JR., professor and chairmanof the Department of Biochemistry;J AMES FRANCK, professor of' physicalchemistry; EUGENE M. K. GElLING,Frank P. Hixon Distinguished ServiceProfessor and chairman of the De­partment of Pharmacology; ANNAHAMANN, assistant professor of roent­genology; R. WENDELL HARRISON, pro­fessor of bacteriology and dean of theDivision of Biological Sciences; PAULC. HODGES, professor of roentgenology;JOHN O. HUTCHENS, director of theToxicity Laboratory and associate pro­fessor and chairman of the Departmentof Physiology; MORRIS S. KHARASCH,Carl William Eisendrath Professor ofChemistry; CARL R. MOORE, professorand chairman of the Department ofZoology; PAUL E. STEINER, associateprofessor of pathology; HAROLD C.UREY, Distinguished Service Professorof Chemistry; and RAYMOND E. ZIRKLE,professor of botany and director of theInstitute of Radiobiology and Bio­physics.To implement this expanded pro­gram of cancer research, there hasbeen formed the University of ChicagoCancer Research Foundation, aninde­pendent corporation under the leader­ship of Mr. Maurice Goldblatt, whosesole objective is to support cancer re­search at the University. It will con­centrate on providing increased facil­ities, laboratories, and buildings for theuse of our scientists. The Foundationplans to provide a laboratory buildingfor nucleonic medicine in which radio­active isotopes can be stored, proc­essed, and used experimentally in thestudy and treatment of cancer as wellas to equip the laboratories and theradiology clinic in the Neoplastic Dis­ease Hospital. The board of trusteesof the Foundation is composed of out·standing leaders of the Chicago com·munity: Graham Aldis, Leigh BlockEdward E. Brown, Britton I. BuddHenry Crown, Robert M. CunninghamThomas B. Freeman, Charles F. GloreMaurice Coldblatt, President, MrsNathan Goldblatt, John R. HurleyJohn S. Knight, Frank McNair, Lawrenee F. Stern, Herman Waldeck, ancEdward F. Wilson.MEDICAL ALUMNI BULLETIN 3SMYTH CALLADINE3Jn jflrmoriamDr. Cornelius A. Hospers, M.D. '32; Ph.D. '32, died in his Chicago homeof coronary thrombosis on February 20, 1947, at the age of forty-two. He wasassistant in pathology at the University of Chicago from 1929 to 1932 andintern in surgery for a year beginning July 1, 1933. Dr. Hospers then becamepathologist of several Chicago hospitals, including among others the Engle­wood, the Holy Cross, and the South Chicago hospitals. During the war heserved as lieutenant colonel and established several European base hospitals.At the time of his death he was pathologist of the Holy Cross Hospital.Dr. Hospers leaves his widow, Lois Ann; a daughter, Jolly Ann; a son,Cornelius J.; his father, Dr. John H., a dentist; his mother, Rosa; and twosisters, Mrs. Helen Yntema and Mrs. Ruth Bohart.Dr. Joseph Norman Smyth, forty-one, a member of our Student HealthDepartment, died in his home on February 23, 1947, of carcinoma of thecolon. He was a graduate of Loyola University School of Medicine, Chicago,in 1933. Dr. Smyth was the son of the late Dr. Joseph P. Smyth and a brotherof Homer and Harlow Smyth. Surviving are his widow, Marian; his mother,Irene; and his three sons, Joseph, Geoffrey, and Thomas.Dr. Thomas Matthew Calladine, twenty-nine, of Woodstock, Illinois, diedin Billings Hospital on February 27, 1947, of testicular embryonal carcinoma.After his graduation from the University of Rochester Medical School in 1943,he was an intern at the University of Chicago Clinics. Dr. Calla dine spenttwenty-seven months as a lieutenant in the Navy and saw service in theChina-Burma-India theater. Following an operation at a China base inJanuary, 1946, he was returned as a patient to hospitals in Bethesda, Mary­land, and Great Lakes, Illinois. Dr. Canadine is survived by his wife, RuthArlene of Woodstock, Illinois; and his mother, Mrs. Thomas M. Calla dineof Rochester, New York.RESIDENT STAFF NEWSLt. Hugh E. Stephenson, Jr., writes fromthe Station Hospital, Fort Baker, San Fran­cisco, that he has traveled 15,000 milesaround the U.S. since completing his in­ternship here last year. He is now chiefof the surgical service in his present loca­tion. He also reads all the X-ray films.Dr. Stephenson has encountered manyfonner Billings people including WilliamWicks at Beaumont General in El Paso,Lynn Hallinger, Joe Larner, Talso, Burns,Choy, Giovachinni, Pope, and others inSan Antonio. Duke Choy has recently hada daughter and is being stationed inHawaii.Dr. Thomas S. Saunders, resident in:lennatology, '33-'34, has practiced der­:natology in Portland, Oregon, for the last.en years. He is assistant clinical professor)f dermatology and syphilology at the Uni­versity of Oregon Medical School. He alsoierved as secretary of the Oregon StateMedical Society for the last three years.Lt. (jg) Jay Bartlett, former surgical assistant resident, is still located at theNaval Hospital in San Diego, where heis doing neurosurgery.Dr. George E. Poucher, resident in psy­chiatry, '40-'41, is now engaged in privatepractice in psychiatry at 1414 Clark Build­ing, Pittsburgh, Pennsylvania.Dr. Leffie Carlton, former surgical as­sistant resident, is in practice with hisuncle in Tampa, Florida.Dr. Irvin B. Gardner has opened hisoffice at 411 Primrose Road, Burlingame,California, after four years in the ArmyMedical Corps.Dr. 1. Antonio Berumen of MexicoCity and Dr. Reynaldo A. MilIa of ElSalvador are now assistant residents inanesthesiology at the University of Chi­cago.Dr. Walter J. Aagesen was back in prac­tice in Anderson, Indiana, for one year onMarch first, after a five-year stretch inthe Army. Dr. Louis Rubin, '43, has returned fromArmy service and is now assistant residentin Dermatology.Dr. Paul W. Schafer is now assistantprofessor of surgery at the University ofKansas Medical School, Bell MemorialHospital, Twenty-ninth and Rainbow,Kansas City, Kansas, and consultant inthoracic surgery at the Veterans Hospital,Excelsior Springs, Missouri.John J. Fahey, a former resident in or­thopedics and now a member of the ortho­pedic staff of the University of Illinoisand attending surgeon at St. Francis Hos­pital, Evanston, and Michael A. Di Cosolawere awarded the gold medal for orig­inality of presentation and research at theannual meeting of the American Academyof Orthopedic Surgeons. Their scientificexhibit was on "Experimental Dislocationof the Shoulder."Dr. Samuel T. Thierstein, resident inobstetrics and gynecology, '42-'43, be­came associated with the Olney Clinic inLincoln, Nebraska, last summer afterseventeen months in the Pacific.Lt. Peter Talso visited the Clinics inDecember. At that time he was stationedin the Research Laboratory at Fort Knox,Kentucky, and his family was locatedthere also.Dr. Charles E. McLennan, intern inobstetrics, '35, will become professor andexecutive head of the department of ob­stetrics and gynecology at Stanford Uni­versity School of Medicine on August l.Dr. Henry N. Harkins, associate pro­fessor of surgery, Johns Hopkins Uni­versity School of Medicine and Johns Hop­kins Hospital, has resigned to become, onJuly 1, professor of surgery and executiveofficer of the department of surgery atthe new medical school of the Universityof Washington, Seattle. He was a recentClinics visitor. Dr. Harkins is a formersurgical resident and instructor of surgeryat this institution.Dr. John S. Howe, intern in surgeryand gynecology, '32-'34, resigned as pro­fessor of pathology at the Medical Collegeof Virginia last September in order toaccept an appointment as pathologist anddirector of laboratories at the MethodistHospital, Brooklyn, New York.Dr. Paul Guerin, who is now in theArmy, was a Clinics visitor early in April.He is stationed at Valley Forge Hospital,Phoenixville, Pennsylvania, on an ortho­pedic service.Lt. George McMurtrey, a member ofthe air-borne paratroopers, visited theClinics April 2 on his way to Atlanta. Hehad just returned from nearly a year inGermany, where he was stationed in theMunich-Frankfurt area.. Dr. Andrew Brislen, '34, and Dr.Myron Hipskind are sharing an office inChicago and are both on the staff of theWoodlawn Hospital.(Continued on page 5)4 MEDICAL ALUMNI BULLETINSCI E'N T I F I C SECTIONNitrogen Mustard Therapy ofNeoplastic Diseases and AlliedDisorders of the HemopoieticSystemLEON O. JACOBSON ANDCHARLES L. SPURRMore than seventy patients withneoplastic and allied disorders of thehemopoietic system have been treatedduring the last four years by the intra­venous administration of methyl-bis(B-chloroethyl) amine hydrochloride.The diseases treated with this nitrogenmustard include Hodgkin's disease, lym­phosarcoma, multiple myeloma, acuteand chronic lymphatic leucemia, acuteand chronic myelogenous leucemia,and polycythemia rubra vera. Thedosage of the drug used in these caseswas 0.1 mg. per kilogram of bodyweight given in courses of one to sevendaily injections. Usually, however, acourse of treatment is confined to fourdaily injections. Although signs andsymptoms of drug toxicity occur, theyare not serious. Nausea and vomitingalmost invariably follow within threeto four hours after an injection of thedrug but can usually be minimized byadequate barbiturate sedation. Throm­bophlebitis is avoided by adequate di­lution of the drug. Leucopenia andthrombocytopenia of varying severityfollow a course of treatment withintwo to three weeks. No serious hem­orrhagic complications have occurred,nor has secondary infection been aserious problem.Patients have been observed afterSingle or repeated courses of nitrogenmustard from two to forty-eightmonths. Clinical remissions of fromzero to twenty-four months have beenproduced with a single course of treat­ment. Whereas the course of acuteleucemia and multiple myeloma areunaffected by this drug, Significantclinical remissions have been repeated­ly produced in Hodgkin's disease, lym­phosarcoma, chronic lymphatic leu­cernia, chronic myelogenous leucemia,and polycythemia rubra vera. Of thesediseases, the most encouraging resultshave been seen in Hodgkin's disease.The common symptoms of fever, pru­ritus, and malaise are frequently re­lieved within a period of a few daysafter the initiation of treatment. Lym- phadenopathy, splenomegaly, and he­patomegaly usually regress more slow­ly but in favorable cases have returnedto normal in three weeks or less. Ofmore than forty patients with Hodg­kin's disease who have come under ourcare, fourteen had previously beentreated extensively with X-ray therapywith brief and unsatisfactory remis­sions. Seven of these cases continue torespond well to nitrogen mustardtherapy. Two of these fourteen casesfailed to show a satisfactory remission,and in five a single remission of fromthree to 'ten months was produced,death following.The combination of local X-ray ther­apy and systemic treatment with thenitrogen mustards has already shownpromise in the treatment of certain ofthese diseases. No clear-cut advantagehas been noted in combining nitrogenmustard therapy with urethane orradiophosphorus. The search for chem­otherapeutic substances which will per­manently control the course of thediseases discussed above must go on.It is obvious that this nitrogen mustardis not the answer. However, it offershope that other chemotherapeuticagents may be found which will moreeffectively control or cure neoplasticdiseases.Studies of the Bacterial Floraof the Normal and Patho­logical Vagina and Uterus(AN ABSTRACT)K, EILEEN HITE ANDH, CLOSE HESSELTINEDepartment of Bacteriology and Para­sitology and the Department ofObstetrics and GynecologyNumerous bacteria have been in­criminated as the cause of puerperalinfection, but the etiological role ofmany is doubtful, since the same typeshave been isolated from the normalgenital tract and since the results ofdifferent investigators are variable,Consequently, the first stage of our in­vestigation of puerperal infections hasbeen to survey the bacterial flora ofthe genital tract. A total of 250 cul­tures has been made of material fromthe vagina of 60 normal prenatal and94 pathological (73 trichomoniasis and 21 other vaginitis) patients and theuterine cavity of 50 afebrile puerperaeand 45 postabortal and febrile (chieflyendometritis) patients. The flora of thevagina of the normal and mixed vagini­tis groups were remarkably similar.The incidence of aciduric rods, (Doder­lein) , Staph. albus, diphtheroid rods,and fungi was high, whereas other or­ganisms were infrequently encoun­tered. Cultures from the trichomoniasisand postpartum (both normal and pa­thological) patients differed from theabove but were very ,similar �o eachother. Aerobic staphylococci, nonhcmo­lytic (both green-producing and indif­ferent) streptococci, anaerobic strep­tococci, and micrococci as well asanaerobic nonsporulating rods, such asBacterium necrophorum and B. mela­ninogenicllm, were frequently present.Diphtheroid rods were not more fre­quent than in cultures from the normalvagina. A study of the aerobic strepto­cocci showed that they belong to sev­eral groups (Sherman) including thepyogenic, the viridans, and the entero­coccus groups, although some couldnot be classified, Of these oiganisms,the enterococci were found to be re­sistant to penicillin.These results imply that the devel­opment of puerperal infection may attimes depend upon infection with par­ticularly virulent strains, the synergis­tic action of mixed bacteria and/oralterations in host resistance ratherthan upon infection with a specific bac­terium. Furthermore, the postpartumuterus is incriminated as a portal ofentry for organisms, such as the strep­tococci. Additional work is in' progress,Pathology Group StudiesProtein ProblemsThe problems of protein and aminoacid nutrition as well as certain aspectsof amino acid metabolism are heing in­vestigated by a group of workers in theDepartment of Pathology. The projectis under the direction of Dr. Paul R.Cannon, professor and chairman of thedepartment. Amollg those partidpatingin the study at the present time are Dr.E. M. Humphreys, Dr. Earl P. Benditt,Robert VV. Wissler, C. Harold Steffee,Robert L. Woolridge, Dr. Robert Step­to, Lawrence Frazier, Olaf K, Skinsncs,Dr. :-'-1. Azirvadham, Dr. Erling Strux-MEDICAL ALUMNI BULLETIN 5ess, Donald Rowley, Norman Jen­ings, Dr. Matthew Kobak, Dr. Johnobin, and Dr. Murray Dworetsky.From the beginning of the study in:}41 the pathologic aspects of proteineficiency have been explored. Thisabject has assumed greater impor­moe due to the increase in world-widendernutrition. Furthermore, clinicianss well as pathologists are becominglore aware of the large tissue-proteinisses which accompany many diseases.Much of the early work of the group'as concerned with the effect of pro­ein depletion upon antibody produc­on. It was observed that rabbits andits fed low protein rations showed areatly diminished capacity to formntibodies in response to several typesf antigens. This diminished antibody�sponse has been found to be an im­ortant factor in the increased mor­rlity of protein-deficient rabbits andats following induced acute andhronic infections. Even the fowl,-hich is normally very resistant to theneumococcus, dies of septicemia whenifection follows protein depletion.Other experiments have demon­:rated that protein-starved animalssquire extended chemotherapy (pen­eillin) 'compared to their controls toasure recovery from a pneumococcalifection, Apparently this is due to theecreased capacity of depleted tissues) aid the chemotherapeutic agent.'urthermore, only a low humoral an­.body level is developed by such ani­rals during infection.Another phase of the study has beenre evaluation of the nutritive poten­.alities of various proteins. During the/ar a rapid rat-repletion method waseveloped by the group to measureae fabrication of several protein com­orients of the body in response to theeeding of test materials. At the re­uest of the Quartermaster Corps thisiethod was utilized to assay many ofre Army emergency rations and in­redients and the effects of processingnd storage upon them. Blood substi­.ites, protein hydrolysates, and reliefations have been similarly evaluated..specially important was the demon­tration that suitable amino acid or pro­sin supplementation could <;10 much) improve the protein quality of theseubstances,More recently the attentions of theroup have been focused upon the£fects of single amino acid deficien­ies. In these experiments the dietaryitrogen is furnished by sixteen puri­ed amino acids which are incorporated1 rations adequate in other food mate- rials. The removal of anyone of thenine indispensable amino acids (ex­cluding arginine) leads to a promptrejection of the ration by the test ani­mal. This is accompanied by a markedloss of weight and blood proteins.Further experiments are under way toelucidate the mechanism underlyingthis dramatic effect and to explore itspossible relationship to the negativenitrogen balance which follows burns,fractures, and other forms of tissue in­jury.Other experiments nearing comple­tion have utilized the protein-deficientrat to establish the minimal essentialamino acid needs of the animal fortissue synthesis. Similarly the quanti­tative requirements of each essentialamino acid for the maintenance of ni­trogen equilibrium have been deter­mined. The results of these experi­ments indicate 'that amino acid require­ments for adequate tissue synthesis inthe presence of protein deficiency arenot only greater than those for main­tenance but also require the indis­pensable amino acids in different pro­portions.Among the other problems being in­vestigated by various members of thegroup are (1) the relationships be­tween caloric and protein requirements,(2) the relative capacities of differenttissues to fabricate protein under vary­ing circumstances, (3) the influence ofvitamin deficiencies upon protein syn­thesis, (4) the effects of protein de­ficiency upon the bone marrow andthe leucocyte response to stimuli, (5)the relationship between endocrineimbalance and protein metabolism, (6)the effects of protein depletion onwound healing, and (7) the relativeutilizability of the d and I forms ofvarious amino acids.Awards Received for Exhibitson Gelatin Sponge for Con­trol of Hemorrhage1. Illinois State Medical Society-Certif­icate of Merit, May, 19462. American Medical Association-Honor­able Mention, July, 19463. Mississippi Valley Medical Society, St.Louis-Silver Medal, First Prize, Sep­temher, 19464. Latin-American Medical Asrociation,Mexico City-Gold Medal, SecondPrize, November, 1946The work on gelatin sponge has beendone by Dr. H. P. Jenkins in collabora­tion with Drs. Rohert Jampolis, EdwardSenz, Howard Owen, Rudolph Janda,James Clarke, and Peter Moulder. Thiswork is being reported in the literature in a series of articles of which five havebeen published and three are in press, Inaddition, a forty-five-minute motion pic­ture of these studies has been completedand has been approved by the AmericanCollege of Surgeons.Resident Staff News­(Continued from page 3)Lt. Douglas Morton was a Clinics visi­tor in May. He is now in charge of surgeryat the AAF Station Hospital at FortGeorge Wright, Spokane, Washington.The Mortons have been given excellentliving quarters on that old Army post.Dr. A. K. Rodholm has joined theMoody Clinic at Corpus Christi, Texas.Dr. Donald Ross is now a member ofthe Christie Clinic at Champaign-Urbana,Illinois.Dr. Ying Tak Chan, an early Billingsassistant resident, has arrived in this coun­try after nine years of war experiences inChina. Shc visited the Clinics in April onher way to Washington and New York,where she will begin work on a one- totwo-year Ortho Research Foundation For­eign Visiting Fellowship for MaternalHealth Problems. She will eventually coverseveral maternity centers in this country.Dr. Chan had an eighteen-day stormycrossing on a former troopship, "The Gen­eral Gordon," and they stood by for twodays in the rescue from the oil tanker thatsplit in two in the Pacific.Dr. Francis Phillips is going, on July 1,to Temple, Texas, where he has been ap­pointed senior thoracic surgeon at a five­hundred-bed chest hospital of the VeteransAdministration.AWARDSDr, J. R. Blayney, director of theZoller Memorial Dental Clinic, has re­ceived the Ohio State Dental Society'sJohn R. Callahan Award given annu­ally for outstanding performance indentistry.Dr, Matthew Block, '43, has beenawarded the four-hundred-dollar 1946Joseph A. Capps Prize for MedicalResearch, according to an announce­ment by the Institute of Medicine ofChicago. His work was on "Sequelaeof Trench Foot-Anatomic Study."RESEARCH GRANTSTO U. OF G. FACULTYThe Illinois division of the AmericanCancer Society on March 17 announcedgrants of $69,115 to twelve Chicagoansfor cancer research. In our institutiongra�ts were made as follows: Dr. E. S.Cuzman Barron, $10,000; Drs. Leon O.jacobson, Austin Brucs, Charles L. Spurr,and Mathew Bloch, $9,120; Dr. Allan T.Kenyon, $6,300; and Dr. P. E. Steiner,$3,000.6 MEDICAL ALUMNI BULLETINALUMNI NEWS'32. Alven Weil has returned from serv­ice in the medical corps and has resumedhis private practice in obstetrics andgynecology at 1030 First Central Tower,Akron, Ohio.Capt. Arthur J. Worwald, U.S.N., headof the Medical Science Section, Office ofResearch and Inventions, in the office ofthe Secretary of the Navy, Washington,D.C., was a clinics visitor in April.'34. Nathaniel Safran is now practicingradiology at Devereux Professional Build­ing, 468 Delaware Avenue, Buffalo, NewYork.Sarah E. Branham was married to Dr.Philip S. Matthews on December 22, 1945.She is senior bacteriologist in the BiologicsControl Laboratory of the National Insti­tute of Health, which is the Research Di­vision of the U.S. Public Health Service.James W. Hall is in practice in internalmedicine in Traverse City, Michigan, andwrites that he is greatly enjoying theNorth Country.'36. Monroe K. Ruch is chief of thePlastic Surgery section at the McCormackGeneral Hospital in Pasadena, California.He writes that he is waiting to get "un­frozen" and start practice, probably inLos Angeles. This is the third plasticcenter in which he has worked since hisreturn from ETO, where he toured fromNormandy to Austria as chief of a maxillo­facial team (4th Aux. Surg. Gp.). He hastwo boys, aged eight and eleven.'37. Leo Rangell was discharged fromthe Army in May, 1946, after serving forthree and a half years as a neuropsychi­atrist with the Army Air Forces. He is nowpracticing psychiatry and neurology at405 North Bedford Drive, Beverly Hills,California.'38. Charles C. Scott is the author (withE. B. Robbins and K. K. Chen) of anarticle entitled "Comparison of Some NewAnalgesic Compounds" in Science, 104,No. 2712 (December, 1946),587--88. Thearticle deals with studies of new analgesicagents prepared by German chemists dur­ing the war. The work was done at theLilly Research Laboratories, Indianapolis.Ralph P. Christenson is in private prac­tice, largely obstetrics and gynecology, at825 Miner Building, Eugene, Oregon.Carl D. Strouse is an instructor in medi­cine at the University of Southern Cali­fornia and doing part-time teaching ofjunior students in the wards of Los AngelesCounty Hospital.'39. Robert Warner is now at the Cin­cinnati Children's Hospital and ResearchFoundation after five years in the Army.Ruth I. Barnard has just completedthree years at the Menninger Foundation,where she is assistant medical director and Winter Veterans Administration Hospitaland teaches in the Menninger FoundationSchool of Psychiatry. She writes that BillLewis, '41, Byron Casey, '43, and DavidRubinfine, '44, are fellows in the Schoolof Psychiatry. Also Merton Gill, '38, ison the staff of the Menninger Foundationand a consultant at the Winter VeteransAdministration Hospital.'40. Edward Whiteley is now in Kassel,Germany, and has had his family withhim since July, 1946. In July he will re­turn to the United States and hopes tostop in at the Clinics to say hello to allhis friends.Walter A. Stryker was professor ofpathology at the University of Michiganuntil July I, 1946. He is now in privatepractice in Detroit.'41. Clara Johns is the new health of­ficer for Lee County Health Departmentwith headquarters at Dixon, Illinois.Owen Berg is now practicing urologyin Milwaukee and is an occasional Clinicsvisitor.Harry P. Maxwell has been practicingneurological surgery for a year and a halfnow since finishing his residency at theUniversity of Illinois under Drs. Oldberg,Bailey; and Bucy. He and Mrs. Maxwellare the proud parents of nine-month-oldtwin boys.Robert B. Sweet, who was in the medi­cal corps of the U.S. Army Air Force andserved in England, is now at the Univer­sity of Michigan Hospital in the Depart­ment of Surgery as a resident.'42. Lyndon M. Hill is now resident insurgery at Harlem Hospital, New YorkCity.Herbert D. Trace is serving a surgicalresidency at Cook County Hospital.Frank H. Belfus is at present a residentin the Department of Internal Medicineat Columbia Hospital in Milwaukee. Hehas been working in part under Dr. El­wood Mason, who was a resident and in­structor in medicine here from '33 to '36.Robert R. Morris was released fromactive service as Lieutenant (M.C.),USNR, on July 8, 1946, after five monthsat the U.S. Naval Hospital in Bethesda,Maryland. Since September, 1946, he hasbeen a staff physician at St. Elizabeth'sHospital, Washington, D.C.Charles F. Williams is now a fellow ininternal medicine at the University ofMinnesota.Isadore Rossman served thirty-ninemonths in the Army, winding up as chiefof medicine at Mason General Hospital.He is now resident in medicine at Monte­fiore Hospital, Bronx, New York.Harlan Carey, Jr., has returned fromArmy. s��ce .and is now assistant resident Peter Beal, on a one-year leave of ab­sence from the dermatology department,is working on "dermatrophic" viruses. Hehas a National Research Fellowship andis working in the Virus Laboratory, 1392University Avenue, Berkeley 2, California,which is connected with the CaliforniaDepartment of Public Health. -The virusresearch is carried on under the auspicesof the International Health Division ofthe Rockefeller Foundation. Dr. Beal hasrecently visited the Kahouns. Jack Kahounis still at Mare Island finishing his Navyinternship and will soon go to Pensacola,Florida, for flight-school training.'43. Colin G. Thomas was married toShirley Forbes on September 14, 1946.At present he is chief of surgery, StationHospital, Fort Monmouth, New Jersey.Robert L. Smith is now engaged in thepractice of general medicine with Leo R.Hawkes, a 1939 graduate of Rush. Hewas discharged from the Navy in May,1946.David Minard is again a civilian aftertwo years in the Navy. He saw some ac­tion at Okinawa and later spent six monthsin Tokyo Bay. He returned to the Statesin August, 1946, and took up his presentduties at the Naval Medical Research In­stitute, where he is assigned to the phys­iology facility.LaRele J. Stephens, who is back on thecampus interning in obstetrics and gyne­cology, spent two and a half years withthe Navy and Marine Corps in the Asiatic­Pacific theater and for the last. eightmonths had been running a small hospitalin a "primitive" part of Idaho.John J. Schneider is at present a re­search associate in the Chemistry Depart­ment of Mayo Clinics. Other U. of C. menat Mayo Clinics are Van Hunt, '44,Robert Painter, '41, and Walter Cox, '43.Charles P. McCartney is out of theArmy and is an intern at Lying-in.Ralph J. Bailey complete his appoint­ment at the U. of C. as Kellogg Fellow inRoentgenology and has gone into prac­tice in Chicago with Dr. William Anspach,a former member of our roentgenologyfaculty.William Webster has returned to theClinics as assistant resident in urology.G. Arthur Mulder has just been dis­charged from the Army after having spentseven months with the Fifth Air Force inJapan. Prior to that he had been stationedat Foster General Hospital in Jackson,Mississippi, and Kennedy General Hos­pital in Memphis, Tennessee. He is nowcompleting his surgical residency at But­terworth Hospital, Grand Rapids, Mich­igan, which he started before enteringMEDICAL ALUMNI BULLETIN 7Alfred J. D'Alessandro is at present asidcnt at the Medwood Hospital inooklyn.Robert M. McCormack is chief of handrgery at the William Beaumont Cen-11 Hospital in El Paso, Texas. He plansreturn to Strong Memorial Hospital formpletion of his training in plastic sur­ry following separation in June.'44. Jack Farber, who recently returnedrm Japan, has become associated withrs. Wiese, Palmer, Belknap, and EmmettOntario, Oregon, where he is going into.diatrics.Capt. Frank P. Evans is chief of neuro­ychiatry at Fort Benning, Georgia.Hugh A. Frank is in private practice insociation with two other doctors in Elijon, California. He writes that he hasen both Drs. Trotter recently and thatey are practicing in San Diego.Virginia McDonald is now a voluntarysistant in pediatrics at the U. of C.'45. Lt. (jg) James S. Miles wrote inecemher from the Veterans Administra­m Hospital in San Fernando, California,at he misses a good medical library. He»uld like to trade their three- and four­LY rainstorms for a nice stiff wind on theidway.Lt. (jg) Howard Reiser is still at thewy Base, Portsmouth, New Hampshire,here he is assigned to the U.S. Navalison (Disciplinary Barracks). All theirteresting medical cases and surgicalses, except minor lacerations, etc., must, sent to the near-by Naval Hospital, sos service is hardly interesting or in­rrnative.'Woodrow Kash is now junior residentmedicine at Mercy Hospital and Loyolaniversity Clinics, Chicago.Harry W. Fischer writes that he is,ing transferred to a new V.A. hospitalTomah, Wisconsin. "This hospital is toovide care for chronic psychotics. Re­ining an interest mainly in surgery, and.ving scrubbed twice in eight months,BULLETIN)f the Alumni AssociationIhe University of Chicago'}(f;HOOL OF MEDICINEVOL. 3 JUNE 1947 No.2W. H. T. MURRAY, EdilDrHUBERTA LIVINGSTONE, Associate EditorHENRY T. RICKETTS, Associate EditorWILLIAM B. TUCKER, CLAYTON G. LOOSLIAssistant EditorsALLAN T. KENYONFRANCIS B. GORDONHILGER P. JENKINSMembers of I". Editorial BoardMAillE ECKERT, SecretaryPrice of yearly subscription for nonmembers, $1.00;nice of single copies, 25 cents. I feel the new situation cannot be muchworse than my previous assignment ata N.P. hospital in Mendota, Wisconsin."Dr. Fischer reports that his internship insurgery at Barnes Hospital (WashingtonUniversity Medical School) in St. Louiswas excellent and that he hopes to returnthere for his resident training in generalsurgery when the Navy releases him fromhis present duties.George Krakowka has just been ap­pointed as chief of X-ray at the VeteransHospital, Fort Harrison, Montana, to re­place Dr. Alfred Benesch, '33, who hasbeen transferred to Portland to completehis boards in radiology.Loren T. DeWind is in the Army andstationed at the Veterans Hospital at Chil­licothe, Ohio. As he is the only represen­tative of the U. of C. there, he writes thatletters from classmates are most welcome.Thomas W. Anderson in January waslocated at the Naval Dispensary, Adak,Alaska, where there was no shortage ofdoctors. He has become a chess addict.Lt. (jg) C. F. Kittle, stationed at theVeterans Hospital, Los Angeles, Cali­fornia, spent a brief period in Chicagothis winter.Everett Van Reken is planning to goto China to take up work at a mission hos­pital with his wife and two children inAugust of this year.Robert Langdon is now stationed atBrown General Hospital in Dayton, Ohio,which is part of the Veterans Administra­tion Facility.Thomas G. Harward is senior medicalofficer aboard a repair ship, the "ussHooper Island," which is stationed atTsingtao, China. He writes that HenryMcWhorter, '44, is senior medical officeron the "uss Piedmont," another repairship at Tsingtao. Ray Goodman, '44, isnow at a Marine Base Hospital in Tiensin,China, and Ed Horner, '45, was in Tsing­tao in January and from there went toJapan.Warren F. Wilhelm and his familyvisited the U. of C. campus this winter.Warren is now the ward officer of theMedical Service Station Hospital, CampMcCoy, Wisconsin.'46. Clair E. Basinger finishes his in­ternship at the Chicago Memorial Hos­pital in April and then is going to workfor Dr. Francis Phillips, formerly instruc­tor in surgery at the U. of C. Clinics, inMarquette, Michigan. Dr. Phillips becamedirector and surgeon-in-chief of theMorgan Heights Sanitarium on July I,1946.John W. Cashman reports that he isenjoying his internship at the Kansas CityGeneral Hospital, after which he intendsto substitute a tour of duty with theUSPHS for his Army obligation.'47. William Beach is interning at theAlameda County Hospital and recentlypaid a visit to Dr. Whitecotton. He has alsoseen Greg Thomas, '46, Dick Taylor, '46,and Ruth Perkins, '45, who all assure himthat the internship is an excellent one. BIRTHSDr. and Mrs. W. A. Stryker, Sara Margaret,April 12, 1946Dr. and Mrs. P. L. Beal, Eric Alan, May22, 1946Dr. and Mrs. R. G. Langdon, CeceliaMarie, May 27, 1946Dr. and Mrs. J. E. Harvey, RoderickWilson, June 18, 1946Dr. and Mrs. W. B. Cox, Douglas, June27, 1946Lt. and Mrs. M. Bonfiglio, Robert, Sept.,1946Dr. and Mrs. L. D. DeWind, Sharon Ruth,Sept. 6, 1946Drs. Jonathan and Teresa (Folin) Rhoads,Philip Garrett and Charles James, Oct.7, 1946Dr. and Mrs. W. B. Tucker, Sara Wait­still, Oct. 23, 1946.Dr. and Mrs. R. L. Smith, Craig, Nov. 6,1946Dr. and Mrs. Theron Hopple, Carol Faye,Nov. 24, 1946Dr. and Mrs. Robert Warner, Robert, Dec.2, 1946Lt. and Mrs. W. F. Wilhelm, RichardWarren, Dec. 17, 1946Dr. and Mrs. Andrew Brislen, Donn Fran­cis, Jan .. 5, 1947Dr. and Mrs. L. M. Hill, Jr., LyndonMichael, Jan. 8, 1947Dr. and Mrs. Francis Phillips, Susan Me­lissa, Jan. 28, 1947Dr. and Mrs. Erwin Levin, Barry, Feb.11,1947Dr. and Mrs. E. L. Borkon, daughter, Feb.14, 1947Dr. and Mrs. W. Neuman (Dr. BarbaraSpiro), Thomas George, Feb. 15, 1947Dr. and Mrs. Jay Jacoby, Jane Alice, Feb.28, 1947Dr. and Mrs. C. M. Johnson, Jr., CharlesMichael III, Feb. 28, 1947Dr. and Mrs. Howard Owen, GregoryScott, March 10, 1947Dr. and Mrs. R. F. Carlson, David John,March 12, 1947Drs. Leonard and Dorothy Ritzmann,Mary, March 21, 1947Dr.' and Mrs. Pompeyo Chavez (SabraNichols), Lucy Ellen, March 23, 1947Dr. and Mrs. Milton Landowne, Joseph,March 31, 1947Dr. and Mrs. Henry Hopple, GretchenMarie, March 24, 1947MARRIAGESDr. A. J. D'Alessandro, Lenore Holoviak,Sept. 14, 1946Dr. M. P. Woolf, Madelyne MarthaStudent, Nov. 17, 1946Dr. H. N. Gordon, Margery Elvis Lynch,March 7, 1947Dr. Richard Kershner, Marian Lumpkin,March 22, 1947Dr. W. C. Drennan, Doris Peoples, May10, 19478 MEDICAL ALUMNI BULLETINFACULTY NEWS. Dr. Jules H. Masserman, until recentlya member of our psychiatry department,and now connected with NorthwesternUniversity Medical School, has been citedby the Lasker Foundation for his outstand­ing research in psychiatry and its appli­cation to mental hygiene.Dr. William E. Adams was electedtreasurer of the American Association forThoracic Surgery.Dr. Arno B. Luckhardt, professor of'physiology, has been designated Distin­guished Service Professor of Physiology,effective July 1, 1947.Dr. Victor E. Johnson, Ph.D. '30, M.D.'39, has been appointed to the post of di­rector of the Mayo Foundation for MedicalEducation and Research, to succeed Dr.Donald Balfour when he becomes direc­tor emeritus in 1947. Dr. Johnson willalso be professor of physiology at the Uni­versity of Minnesota. He joined the staffof the Mayo Foundation in April and willbecome director in October.Dr. N. Paul Hudson, formerly a mcm­ber of the U. of C. faculty and now pro­fessor and chairman of the Departmentof Bacteriology, Ohio State UniversityCollege of Medicine, has been appointeddean of the graduate school at that in­stitution.Dr. Anton J. Carlson, president andscientific director of the Research Councilon Problems of Alcohol, took part in aconference on alcoholism as a publichealth problem on February 12, in RodgerYoung Auditorium, Los Angeles.Dr. Alfred Joseph Klein, assistant pro­fessor of medicine, has resigned. In March he went into private practice in EauClaire, Wisconsin.Dr. Huberta M. Livingstone was in­vited by the Mexican Society of Anes­thetists to take part in the first Congressof Mexican Anesthetists which was heldin conjunction with the Seventh Congressof Surgeons and Second Congress ofBlood Transfusions in Mexico City in No­vember. Dr. Livingstone and Dr. JoaquinCoto (voluntary assistant in anesthesi­ology) presented a paper on "AnestheticMortality in Intrathoracic 'Surgery."Dr. J. Robert Willson, assistant pro­fessor of obstetrics and gynecology re­signed on January 1 to become head ofthe department of obstetrics and gyne­cology at Temple University School ofMedicine and Hospital.Dr. A. Earl Walker, professor of surgery( neurosurgery), has returned from a planetrip to South America, where he presenteda paper on "Advances in Electroenceph­alography" at the Second South AmericanNeurosurgical Congress held in Santiago,Chile, April 21-22. While in South Amer­ica he visited hospitals in Chile; Lima,Peru; Buenos Aires; Montevideo; and Riode Janeiro.Dr. John R. Lindsay has been electedpresident of the Chicago LaryngologicalSociety.Dr. Alexander Brunschwig will be amember of a team of ten health expertssent to Austria and Hungary this summerby the Interim Commission of the UnitedNations Health Organization. The group,which leaves the states on June 26, willexplain the latest advances in medicineto Austrian and Hungarian doctors. Dr. Charles L. Dunham, assistant pro­fessor of medicine, on February 15 beganpart-time service in the U. of C. Devel­opment Office as Biological Sciences rep­resentative.Dr. Fred L. Adair, emeritus professorof obstetrics and gynecology, has returnedfrom Argentina, where, under the spon­sorship of the U.S. Department of State,he served as visiting lecturer in obstetrics.He was invited by the Society of Obstetricsand Gynecology of Argentina as a specialdelegate to the sixth Argentina Congressof Obstetrics and Gynecology and alsogave lectures at the universities in BuenosAires, Cordoba, Santa Fe, and La Plata.Dr. Parker Dooley, associate professorof pediatrics, resigned his position, effec­tive February 1. He is now vacationingat Kent, Connecticut.Dr. Seymour Gray, formerly assistantprofessor of medicine, left the Clinics onNovember 1 and now has an appointmentat Harvard Medical School as assistantprofessor of medicine and is senior asso­ciate of medicine at the Peter Bent Brig­ham Hospital in Boston. He is dividinghis time between duties as director ofhospital gastrointestinal clinic and re­search in the biophysical laboratory. Dr.Gray served as a lieutenant commanderin the Naval Reserve and was stationedat the Naval Medical Center, Bethesda,Maryland.Dr. Russell H. Morgan, associate pro·fessor of roentgenology, left the Clinic!the first of the year to be professor in thenewly created department of radiology atJohns Hopkins University. He is also radi­ologist-in-chief at Johns Hopkins HospitalALUMNI MEETINGThe Annual Alumni Reunion andBusiness Meeting were held in Billings,Friday evening, June 6. Dr. A. R. Mc­Intyre, class of '31, professor of phys­iology and pharmacology at the Uni­versity of Nebraska, spoke on "Curare."Honored guests of the evening were:Dr. Dallas B. Phemister, retiring chair­man of the Department of Surgery;Dr. Lester R. Dragstedt, newly ap­pointed chairman of the Departmentof Surgery; and Dr. Lowell T. Cog­geshall, chairman of the Departmentof Medicine.The following officers were electedfor the coming year: Dr. ClaytonLoosli, president, Dr. Harry Oberhel­man, vice-president; Dr. John VanProhaska, treasurer; and Dr. Charles L.Dunham, secretary. Drs. Leon Jacob­son and F. Joseph Mullin were electedas members of the Council. SERVICE AWARDSCol. Paul A. Campbell, surgical in­terne in 1928-29, has received theLegion of Merit for his work as Direc­tor of Research, Army Air ForcesSchool of Aviation Medicine, fromMay, 1942, to October, 1945.Major Ralph W. Barris, '41, ofGrand Rapids, Michigan, has receivedthe Army Commendation Ribbon forhis meritorious service as chief of theneurology and neuro-syphilis section,Ashfort General Hospital, White Sul­phur Springs, West Virginia, from Sep­tember 24, 1944, to April 11, 1946.Major Oscar Bodansky, '38, of NewYork City, received the Legion of Meritfor exceptionally meritorious service aschief, biochemistry section, and tech­nical director for medical research,medical division, OC-CWS. "His re­searches were indispensable in estab­lishing the mode of action of war gases and developing methods for the treat­ment of casualties. His clearly demonstrated ability to inspire and lead otharesearch workers brought to him positions of major responsibility."The. Army Commendation, Ribberwas recently awarded to Major Andrew}. Brislen, '34, for the high degree of professional ability displaye<in his capacity as chief of the generamedical branch of the medical divisioiat the AAF Regional and ConvalescenHospital, Coral Gables, Florida, iJ1945.Dr. Gail M. Dack, professor of bacteriology and director of the Universitof Chicago Food Research Institutehas been awarded the Exceptional Civilian Service Decoration by the Ann:for his wartime work at Camp DeteriekFrederick, Maryland, center of the blological warfare division. Major GerAlden H. Waitt made the presentatior