�edicine� on the 33 No. 1Bulletin of the Medical Alumni Assoclation ofTheUniversity of ChicagoDivision of the Biological Sciences Jifui The PritzkerSchool of MedicineOCT 3 0 1978Senior students andfaculty on the balcony ofRobie House after the32nd Senior ScientificSession May 17. Photoby Mike Shields.MAILINGPlease send us a change of addressform if you have moved. The costof returning undeliverable copieshas gone up with the mail price in­crease. In the future, with increas­ing costs, it may not be possible forus to forward magazines.Medicine on the MidwayVolume 33, No.1 Summer 1978Bulletin of the Medical Alumni Association of TheUniversity of Chicago Division of the BiologicalSciences and The Pritzker School of Medicine.Copyright 1978 by the Medical Alumni AssociationThe University of ChicagoEditor: Christina West WellsContributing Editor: James S. SweetPhotographers: Mike Shields and David JoelChairman Editorial Committee: Robert W. Wissler('48)Medical Alumni AssociationPresident: Joseph H. Skom (,52)President-Elect: Frank W. Fitch ('53)Vice President: Louis Cohen ('53)Secretary: Sumner C. Kraft ('55)Director: Katherine Wolcott WalkerCouncil MembersRichard H. Evans (' 59)Herbert B. Greenlee (' 55)Abbie R. Lukens ('50)Charles P. McCartney (' 43)- Julian 1. Rimpila ('66)Benjamin H. Spargo ('52)Francis H. Straus, II ('57) ContentsMedical Alumni Day 1978Distinguished Service Award PresentationsAlumni Elect New OfficersSenior Scientific SessionResidency Assignments for 1978Profile-The 1977 Entering ClassA Closer Look: 8 Students After Year 1Dr. Dwight Clark RememberedNews BriefsIn MemoriamDepartmental NewsAlumni NewsDivisional Alumni NewsClass Chairmen Cited for Best FundraisingYear Yet 48111223242633343840424748Medical Alumni Day 1978Alumni, graduating students and faculty members of theDivision of Biological Sciences and the Pritzker School ofMedicine assembled on campus June 8 for the sixth an­nual Medical Alumni Day. Opening the day's activities,Dean Robert B. Uretz welcomed Century Club membersand Class Chairmen at an early morning breakfast held inthe Quadrangle Club. A scientific program featuring thefive Distinguished Service Award recipients finished outthe morning and was followed by an awards luncheon. Areception and dinner at the Hyatt Regency in downtownChicago brought the day to a close, honoring many andwelcoming the Class of 1978 into their profession with arecital of the Hippocratic Oath. When Dr. Joseph H.Skom (,52), the new president of the Medical AlumniAssociation, lowered his gavel at the end of the evening,more than a hundred new physicians, nine reunionclasses, and many alumni and friends of the MedicalSchool parted company after a pleasant and eventful day.Distinguished Service AwardsFive Distinguished Service Award recipients were pre­sented their awards at a luncheon ceremony in WylerChildren's Hospital. (Texts of the presentation speechesbegin on page 8.) Recipients and their topics are:• William C. Dement (,55), The Emergence of SleepDisorders Medicine: Light on the Dark Side of the Moon.Dr. Dement is Professor of Ps ychiatry and Director of theSleep Disorders Center and Sleep Research Program atStanford University School of Medicine in Stanford,Calif.• Louis Gluck (,52), The Prediction of Fetal LungMaturity. Dr. Gluck is Professor of Pediatrics and Re­productive Medicine at the University of California atSan Diego in La Jolla, Calif.• John T. Grayhack (,47), Changes in Prostatic FluidComposition in Association with Prostatic Cancer. Dr.Grayhack is Professor and Chairman of the Departmentof Urology at Northwestern University Medical Schoolin Chicago.• Fenton Schaffner (,43), Hepatitis B Virus and theLiver. Dr. Schaffner is the George Baehr Professor ofMedicine and Chief of the Division of Liver Diseases atMount Sinai School of Medicine of the City University ofNew York in New York City.• Paul Talalay, Carcinogenesis, Mutagenesis and En­zyme Induction. Dr. Talalay is the John Jacob Abel Dis­tinguished Service Professor of Pharmacology and Ex­perimental Therapeutics at Johns Hopkins School ofMedicine in Baltimore.Fifty- Year CitationsTwenty-one members of the Class of 1928 attended theawards luncheon and received fifty-year citations fromCharles P. McCartney (,43), on his final day as presidentof the Medical Alumni Association. Cited were:R.W. BeardsleyEdgar J. ConnellyJacob S. GoldenRobert Moore Jones Roy M. LangdonCharles H. LesageVictor LevineRobert C. Levy4 Robert J. MasonMarque L. JacksonMildred E. NordlundHarold H. ParsonsRaymund M. CassidyVernon W. SchickSamuel A. Scuderi George D. ShawNoel G. ShawS. William SimonFred O. PriestAlexander WolfPaul H. ReedPaul H. Van VerstStudent and Faculty HonorsAt an evening reception and dinner honoring the 1978graduating class, the outstanding achievements of stu­dents and faculty members were recognized.Awards to GraduatesGraduation with HonorsJames Lewis AbbruzzeseErnest BrahnEdward F. GibbonsRick V. HayKenneth Michael Kampman Robert Compton MayKeith Shelby NaunheimEdward Victor ProchownikMary K. RosenowCarol Ann WestbrookAlpha Omega AlphaJames Lewis AbbruzzeseMargaret Mary BarronMitchell Alan BitterRobert Scott BresalierDaniel John DuffeyJames Walter FasulesGary J. FreiEdward F. GibbonsRick V. HayJeffrey Howard HillAmerican Medical Women's Association Awards, towomen medical students for scholastic achievement: Pat­ricia A. McElroy, Anna Elizabeth Muelling, MaryKatherine Rosenow, and Carol Ann Westbrook.Joseph A. Capps Award, to a senior medical student forproficiency in clinical medicine: Robert Compton May.Catherine L. Dobson Prize, to a senior for the best oralpresentation of research done by a non-Ph.D. student:Richard C. Dodd. David Michael JaffePhilip Marc LaughlinRobert Compton MayPatricia A. McElroyKeith Shelby NaunheimAllan Vladimir ProchazkaEdward Victor ProchownikPatricia TroncosoRuth H. WhithamDr. Harold Lamport Biomedical Research Award, forthe best dissertation in biomedical research: James Wen­dell Little.Franklin McLean Medical Student Research Award, to asenior who has performed the most meritorious research:Brooke AlLMedical Alumni Prize, for the best oral presentation ofresearch done during medical school: Carol AnnWestbrook.John Van Prohaska Award, for outstanding potential inteaching, research, and clinical medicine: Edward VictorProchownik.Richard W. Reilly Award, to a senior medical student foroutstanding aptitude in the field of gastroenterology:Frank Anthony Ventimiglia.Sandoz Pharmaceutical Award, in recognition of out­standing performance in the field of psychiatry: AnnaElizabeth Muelling.Mary Roberts Scott Memorial Prize, to a woman medicalstudent for academic excellence: Patricia A. McElroy.Nels M. Strandjord Memorial Award, to a senior medicalstudent for outstanding performance in the general fieldof radiology: James Joseph Langan.Upjohn Award in Medicine, to a senior for outstandingachievement during four years of medical school: Ed­ward F. Gibbons.Awards to FacultyThe Gold Key of the Medical Alumni Association waspresented to Earl A. Evans, Jr., Ph.D., ProfessorEmeritus, Department of Biochemistry and the College.Professor Evans was chairman of the department from1942 to 1972. Prior to that he was an instructor, assis­tant and associate professor of Biochemistry at the Uni­versity. He was named an emeritus professor in 1975.Joseph Ceithaml, Ph.D., '41, Dean of Students, Divisionof the Biological Sciences Division and the PritzkerSchool of Medicine and Professor of the Department ofBiochemistry, presented the award.William Burrows, Ph.D., ' 32, Professor Emeritus, De­partment of Microbiology was also awarded the GoldKey. Professor Burrows taught in the department from1937 to 1973 when he became emeritus. Leon O. Jacob­son ('39), the Joseph Regenstein Professor of Biologicaland Medical Sciences, Department of Medicine and theCollege, made the presentation.The McClintock Award, for outstanding teaching votedby the graduating class, was presented to Dr. Margaret C.Telfer, Assistant Professor, Department of Medicine atMichael Reese Hospital. Dr. Telfer, a hematologist,teaches the junior clerkships in medicine for Universityof Chicago students. She is a graduate of WashingtonUniversity in St. Louis and completed her residency atMichael Reese. Three of the studentshonored at the MedicalAlumni dinner June 8:(Left to right) Edward F.Gibbons, Brooke Alt, andRobert C. May.The Hilger Perry Jenkins Award, given by the gradua­ting seniors for excellence in performance of academicand patient service, was presented to Dr. Stephen Jen­nings ('74). Dr. Jennings is the Chief Resident on theSurgery service where he has been an intern and residentsince his graduation from the Medical School.ReunionsMembers of the classes of 1943, 1948, 1953, 1958, 1963,1968 and 1973 celebrated reunion years. Alumni attend­mg were:Class of 1943 (March): Charles P. McCartney (chair­man), Arthur Loewy, Howard Mauthe, Donald McIn­tyre, Chester B. Powell, Malcolm C. Spencer and MertonWilson.Class of 1943 (December): Robert E. Fitzgerald, Wil­liam J. Hand, Shirley A. Mayer, Robert M. McCormackand William O. Webster.Class of 1948. Asher Finkel (chairman) and WinslowG. Fox.Class of 1953. Frank Fitch (chairman), Paul Anderson,Louis Cohen, Paul Glickman, Charles R. Johnson, Ed­ward Lyon, Fred Matthies, Morris Seide, John S.Thompson and Marvin Weinreb.Class of 1958: Christopher Drake; John T. McEnery;Louis F. Plzak, Jr.; Wendell F. Rosse; Richard M.Rothberg; Henry Rothschild and A. Yvonne Russell.Class of 1963: Rostik Zajtchuk (chairman), Gary L.Gitnick, Michael Kinney, Richard Kraines, Bernard J.Mizock and John Schneider.Class of 1968: Hugh Hazenfield (dinner chairman),Donald Rothbaum, Jerrold H. Seckler and Jack Sipe.Class of 1973: Richard F. Gaeke (chairman), RobertKirk, Michael Silverman and James Weese.5Dr. Catherine L. Dobson with Richard C. Dodd,who was awarded the Dobson Prize.Mrs. Harold Lamport and James W. Little, whoreceived the Lamport Award.Dr. Leon Jacobson ('39) and Gold Key recipientDr. William Burrows (right).6 James Fasules presents Dr. Margaret Telfer with the McClintock Award.William A. Phillips presents Dr. Stephen Jennings (74) with the Hilger Perry Jenkins Award.-.....'American Medical Women's Association Award recipients: (Left to right) Carol A. Westbrook, Anna E.Muelling, Patricia A. McElroy, and Mary K. Rosenow.Members of the Class of '28 at the Alumni luncheon.Medical Alumni Day '78Class of '58 table: (Left to right) Mrs. Henry Rothschild, Dr. Henry Rothschild, Mrs.John McEnery, Dr. John McEnery, Mrs. Louis Plzak, Dr. Louis Plzak, Mrs. RichardRothberg, and Dr. Richard Rothberg.Class of '68 table: (Seated, from left to right) Dr. Jack Sloe, Dr. JerroldSeckler, Mrs. Jerrold Seckler, and Dr. Donald DePinto. (Standing, from leftto right) Ms. Judith Fresinger, Dr. Robert Kirk ('73), Mrs. Hugh Hazenfield,and Dr. Hugh Hazen field. Class of '63 and '66: (Seated, from left to right) Mrs. JohnSchneider, Dr. John Schneider ('63), Mrs. Bernard Mizock, Dr. Be­rnard Mizock ('63), and Dr. Michael Kinney ('63). (Standing, fromleft to right) Dr. Julian Rimpila ('66), Mrs. Julian Rimpila, Dr. JoanZajtchuk ('66), and Dr. Rostik Zajtchuk ('63).Class of '43 table: (Seated, from left to right) Dr. Chester B. Powell, Mrs.Donald Mcintyre, Dr. Donald Mcintyre, and Mrs. Chester Powell. (Stand­ing, from left to right) Mrs. Merton Wilson, Dr. Merton Wilson, Mrs. How­ard Mauthe, and Dr. Howard Mauthe.7The Distinguished Service Award recipients: (Left to right) Drs. Louis Cluck, John T. Crayhack, Paul Ta/a/ay, William C. Dement, and Fenton Schaffner.DistinguishedServiceAwardPresentations8 Dr. William C. DementWilliam C. Dement was born in Wenatchee, Washingtonand received his undergraduate degree summa cumlaude from the University of Washington in 1951. He lefthis home state after college to attend medical school atThe University of Chicago in the Class of '55, and re­mained for two additional years as a post-doctoral re­search fellow in physiology, receiving his Ph.D. in 1957.He traveled further east for his internship at MountSinai Hospital in New York City and was a research fel­low there from 1958 to 1963. Since then he has beenassociated with Stanford University School of Medicineas an associate professor and professor in the Depart­ment of Psychiatry and Behavioral Sciences and Di­rector of the Sleep Research Laboratory. He is currentlyDirector of the Sleep Disorders Clinic and Laboratory.Dr. Dement has authored and co-authored numerousarticles on the subject of sleep research, narcolepsy, andthe neurochemical and neuropharmacological bases ofsleep disorders, among other sleep-related topics. Hefounded the Sleep Review Project of the Brain Informa­tion Service and co-founded the Association for thePsychophysiological Study of Sleep.His honors include the Hofheimer Prize of the Ameri­can Psychiatric Association (1964), the Thomas W. Sal­mon Medal of the New York Academy of Medicine(1969) and an annual research award of the Division ofPsychopharmacology of the American Psychological As­sociation (1970). In addition, he has been elected to theAmerican College of N europsychopharmacology andnamed an Honorary Fellow of the North Pacific Societyof Neurology and Psychiatry.The Distinguished Service Award of The University ofChicago Medical Alumni Association was presented toDr. Dement by Dr. Allan Rechtschaffen, professor in theDepartment of Psychiatry and Behavioral Sciences andDirector of the Sleep Laboratory at the University.Dr. Louis GluckIt is my pleasure to introduce Dr. Louis Gluck, agraduate of the medical school Class of 1952.Following internship at The University of Chicago, Dr.Gluck spent a year in general practice in Harlan County,Kentucky and a year in family practice in New Jerseybefore entering pediatric residency training at BabiesHospital. While at Columbia, Dr. Gluck came under thetutelage of Dr. William Silverman and became a Fellow inFetal Life. Upon completion of his training Dr. Gluckjoined the faculty of Yale University and became the Di­rector of Newborn Services at the Yale-New HavenHospital. It was at this point in his career that Dr. Gluckbegan to be recognized as a leader in the development ofnew concepts in the care of sick newborn infants.He developed an intensive care unit for newborns andpioneered in the change from traditional concepts ofpremature care to modern special care units which wouldserve as referral centers for infants born in outlying hos­pitals as well as for those who were born at the medicalcenters. During this time staphylococcal infection was aproblem of epidemic proportions in many newborn nur­series. Dr. Gluck did some basic epidemiologic researchof the problem and established that the principal mode ofcolonization and transmission was from the umbilicalcord by hand contamination. As a result, primary hospi­tal emphasis shifted to antiseptic skin care and handwashing techniques which were instrumental in control­ling outbreaks of infections.Perhaps Dr. Gluck's most important achievement todate is his work on lung maturation and lecithin/sphingomyelin (US) ratio in amniotic fluid. Dr. Gluck hasdone many fundamental studies in this research area. Hehas demonstrated the correlation between the US ratioand pulmonary maturity, which has proven extra­ordinarily important in managing high risk pregnant pa­tients. It has also provided many insights into our under­standing of pulmonary development. Dr. Gluck continuesto refine and extend this work in a way that clearlycharacterizes him as a leader in the field.Dr. Gluck has authored many scientific papers and hasserved as editor of numerous publications in perinatologyas well as general pediatrics. He has been the recipient ofmany awards including the Yippo award given in Finlandevery five years. Recently, he was the 1978 recipient ofthe Joseph Bolivar DeLee Humanitarian Award here atThe University of Chicago.We are happy to have an opportunity to recognize thisleader in the field of pediatrics as an outstanding alumnusof The University of Chicago.-Dr. John D. MaddenDr. John T. GrayhackIt gives me a great deal of pleasure to be asked to in­troduce Dr. John T. Grayhack and to present this award to him. Dr. Grayhack is an alumnus of The University ofChicago and its School of Medicine, Class of '47. Hetrained in Urology at Johns Hopkins which, as you know,was the birthplace of American urology. Needless to say,it was only the birthplace of American urology becauseDr. Young got to Baltimore before Dr. Huggins got toChicago.Dr. Grayhack became chairman of the Department ofUrology at Northwestern University in 1963, and hasmade the training program at Northwestern one of themost sought after in the United States. He has writtenwidely in the field of urology but his most important re­search contributions have been made in the field of be­nign and malignant prostatic disease, its pathophysiologyand control. For all of us in urology, Dr. Grayhack per­forms another very important service-editing the Year­book of Urology, which through his efforts makes it pos­sible for many of us to stay up-to-date.Dr. and Mrs. Grayhack have five children. One son ispresently an undergraduate in the College. I know thatThe University of Chicago guards these awards jealouslybut I am certain that the University can be proud of hav­ing selected Dr. Grayhack for this award, and I am hon­ored to make this presentation.-Dr. Harry W. SchoenbergDr. Fenton SchaffnerIt is a particular pleasure for me to introduce Dr. FentonSchaffner as the recipient of the Distinguished ServiceA ward. Dr. Schaffner has been a leader in the field ofhepatology for over twenty-five years. Recently, I havebeen privileged to know him as a colleague and friend.He is one of those remarkable individuals who seems tobe able to do many different things well.Indeed because of his national and international re­putation as an excellent teacher and speaker combinedwith his love of travel, Fenton can be found contributingto almost every important councilor meeting devoted tosubjects of the liver. Just tomorrow, he will fly to Londonto deliver a lecture, then return to Chicago to see hisdaughter graduate from law school and then he is offagain. He keeps up this pace all year long and seems tothrive on it.Fenton's contributions to the field of liver disease havebeen extensive and his scientific publications numberseveral hundred. His interest in the liver began in 1948when, following a medical residency, he became a fellowin pathology at Cook County Hospital. At that time liverdisorders were the exclusive domain of the pathologistand he soon came in contact with the Director of Pathol­ogy, Dr. Hans Popper, who stimulated Fenton's interestin the liver. There developed a highly productive re­lationship between the two men which continues today,30 years later, as they actively collaborate as co-editorsin a successful serial monograph entitled "Progress inLiver Diseases" now in its fifth edition.Fenton's early interest in pathology of the liver led himto pioneer in the application of electron microscopy tothe study of both normal and abnormal hepatic structure.Numerous descriptions of experimental human disordersof the liver followed soon thereafter. His publications on9the pathophysiology of cholestasis, a disorder which re­sults in impairment of bile secretion, are classics in thefield.Fenton has also been an effective administrator, andfor many years (1958-1972) he was Secretary for theAmerican Association for the Study of Liver Diseases.He was primarily responsible for the functioning of thisscientific organization which has played a central role instimulating interest in the academic discipline. Fentondid such a successful job in developing the organizationthat it now requires a president, vice-president, numer­ous counselors and committees and other para­professional help to do what he did almost single hand­edly for so many years. In 1977 he served as president ofthe Association.What I find even more extraordinary about Dr. Schaff­ner's career is that throughout these years of enormousactivity he has also maintained a successful academic'clinical practice. Indeed if you have liver disease and livein the New York area, it is likely that you have beenreferred to Fenton. Although his career began inChicago, since 1958 he has been associated with MountSinai School of Medicine in New York, where he is theGeorge Baehr Professor of Medicine as well as Professorof Pathology. His many society memberships, participa­tion in editorial boards, national panels and boards ofgovernors are too numerous to detail. How he has man­aged to do all of this, lecture, travel, be productive inresearch, author so many articles and monographs, andpursue an academic, full-time clinical practice is trulyremarkable.On a personal note, he clearly must be doing somethingright: two of his four children have chosen medicine fortheir own careers; a son is finishing his training in the fieldof gastroenterology at Michigan, while a daughter isabout to begin a medical internship at Yale.Fenton, you were born and brought up in Chicago andlived for twenty years in the University community, youare a graduate of both the University and its medicalschool, and four of your children were born here in theLying-in Hospital. Today you have truly come full circle,it is a great honor for the Alumni Association to presentyou with the 1978 Distinguished Service Award.-Dr. James L. BoyerDr. Paul TalalayIt is a special pleasure to present a Distinguished ServiceAward to a person who is not only an eminent scientistand illustrious alumnus but also a former colleague and apersonal friend.Dr. Paul Talalay received the first two years of hismedical education at The University of Chicago, in thepre-Pritzker era. Here his talents caught the eye of Char­lie Huggins, who offered the young medical student alaboratory bench in the Section of Urology, known inthose days as the Queen of the Sciences, and the oppor­tunity to spend about sixteen hours of his spare time eachday carrying out rather colorful investigations of en­zymes found in the human prostate.For family reasons, it was necessary that Paul com­plete his medical studies at Yale University. Still Paul's10 ties with the Midway persisted, and, after receiving hisM.D. from Yale in 1948 and spending two years as asurgical resident at the Massachusetts General Hospital,he returned to Chicago in 1950, where he became one ofthe founding faculty of the Ben May Laboratory andbegan compiling an impressive batting average of scien­tific accomplishments. In 1963 he was traded to Balti­more in exchange, I am told, for options on managerDave Skinner, put-out specialist Don Benson, and a util­ity outfielder named John Piva. At the Johns HopkinsSchool of Medicine, Dr. Talalay began modestly, as theJohn Jacob Abel Professor and Director of the Depart­ment of Pharmacology and Experimental Therapeutics,and in 1974 he was named the John J. Abel DistinguishedService Professor of that discipline.Professor Talalay is internationally known for manyscientific contributions, the most extensive of which con­cern enzymes that catalyze chemical transformations ofsteroid hormones. He has developed novel enzymologi­cal procedures which have proved of immense value, notonly in providing insight into the molecular actions ofoxidative coenzymes, but also in the estimation and pre­parative interconversion of steroid hormones on a microscale. I can attest personally to the utility of the Talalaytechniques, as certain of our own early studies on theinteraction of estrogenic hormones in target cells wouldhave been impossible had Dr. Talalay not made availablehis 17f3-hydroxysteroid dehydrogenase system, which heisolated from Pseudomonas testosteroni after havingcleverly coerced the unsuspecting microorganism intoproducing this adaptive enzyme.More recently, Dr. Talalay has carried out novelstudies on the biophysical properties of crystalline en­zymes, and he has pioneered in developing rationalbiochemical approaches to therapeutics, as exemplifiedby his detailed analysis of the synthesis and regulation ofS-adenosylmethionine. At our Alumni Day symposiumhe described his recent investigations with glutathionetransferase and its implications in carcinogenesis. In allinstances, Dr. Talalay's investigations are characterizedby elegance and by an exquisite attention to detail.In recognition of his scientific accomplishments, Pro­fessor Talalay has received numerous honors. He hasbeen a John Simon Guggenheim Fellow, a member of theNational Advisory Cancer Council and Editor-in-Chief ofMolecular Pharmacology. While at The University ofChicago he held a lifetime Research Professorship of theAmerican Cancer Society. He is presently on the Boardof Scientific Advisors ofthe Sloan Kettering Institute andof the Jane Coffin Childs Memorial Fund. He is a Fellowof the American Academy of Arts and Sciences, and heholds an honorary degree of Doctor of Science fromAcadia University. He received the Theobald SmithAward of the American Association for the Advancementof Science, and only last week he was in Milan to acceptthe 1978 La Madonnina Prize for Science. We are de­lighted to have the privilege of adding to this list oftributes by presenting Dr. Talalay with the DistinguishedService Award of The University of Chicago MedicalAlumni Association.-Elwood V. Jensen, Ph.D.Alumni Elect New OfficersThe new officers of the Medical Alumni Association for1978-79 were introduced at the Medical Alumni dinnerheld June 8 at the Hyatt Regency in Chicago.The officers are:President, Dr. Joseph H. Skom (,52), associate pro­fessor of clinical medicine at Northwestern Universitymedical school; president-elect, Dr. Frank W. Fitch (,53),the Albert D. Lasker professor of pathology at The Uni­versity of Chicago; Dr. Louis Cohen (,53), professor ofmedicine at The University of Chicago and secretary,Dr. Sumner C. Kraft C 55), professor of medicine at TheUniversity of Chicago.Members of the Alumni Council elected for 1978-81are:Dr. Abbie R. Lukens (,50), a pediatrician in privatepractice in La Grange, Ill.; and Dr. Francis H. Straus II(,57), associate professor of pathology at The Universityof Chicago.* * * * *Dr. Joseph Skom is a graduate of both the College and theMedical School of the University, from which hegraduated with honors in 1952. He interned at JohnsHopkins University and returned to The University ofChicago Clinics for a residency and fellowship in medicine(1953-56).In 1957 he became an instructor in medicine at N orth­western University Medical School where he has re­mained since, currently as an associate professor of clini­cal medicine.Dr. Skom has been active in many state and local med­ical societies. He is the immediate past president of theIllinois Medical Association and past president of theDiabetes Association of Greater Chicago. He has alsoserved on national and state councils on drug use andabuse.Dr. Skom belongs to many professional societies in­cluding the American Diabetes Association, the Ameri­can Heart Association, the Chicago Society of InternalMedicine, and is a Fellow of the American College ofPhysicians.In 1978 he received the Distinguished Service Award ofthe University of Chicago Medical Alumni Association.He and his wife Edith live in Winnetka, Illinois andhave two children, Roger and Harriet, who is a fourth­year medical student at The University of Chicago.RemarksDr. Skom discussed the Medical Alumni Association,its plans for the future, and ongoing programs June 8:"Though many of us have affiliations elsewhere now,when we talk about "the university" we mean The Uni­versity of Chicago; the feeling permeates the graduates ofthis medical school. Even though the student body isfiercely independent and the individuals are not organiza­tionjoiners by and large, they do become involved in theMedical Alumni Association."I have been affiliated with four different universitiesand the spirit here is unique in terms of its paternal at- Dr. Joseph H. Skom (left) talks with Dr. Alvin Tarlov at the Alumni Dayluncheon."I would like to see more of an organized Universityeffort aimed at the grass roots physician ... "titude towards graduates. The alumni association and thefaculty take pride in the accomplishments of graduates.They keep in touch with them and what they are doing."I see the University and its alumni as a family ofchildren, grandchildren and great grandchildren, who arespread out across the country. The alumni associationbrings them together for events like today [MedicalAlumni Day], and I would like to see us bring them to­gether in other ways." An annoying problem that we face now is how can thealumni association, using the resources and personnel ofthe University, make the accomplishments of the faculty,their special skills and teaching better known and moreavailable to physicians in the State and surroundingstates?"Our faculty travel a lot across the country and theworld presenting papers and giving lectures. I would liketo see more of an organized University effort aimed at thegrass roots physician-perhaps through county medicalsocieties, involving alumni in various communities, en­listing their aid in getting University teams and lecturesfor monthly or annual meetings." An idea for a con tinuing education program is ahead yin the process. Since continuing medical education isgoing to be a requirement for relicensure in lllinois andwill become uniform throughout the country, we need tolook at ways in which our faculty and alumni can beinvolved in these programs to benefit both themselvesand the University."IISenior students on the balcony of Robie House after the 32nd SeniorScientific Session May 17.12 Senior Scientific SessionTwenty senior medical students (Class of 1978) presentedreports on their research projects at the 32nd AnnualSenior Scientific Session held May 17. Chairmen of thefour-part program were: Dr. Godfrey S. Getz; Robert B.Uretz, Ph.D.; Dr. Irwin H. Rosenberg; and Dr. Louis M.Sherwood. Members of the Committee on Arrangementswere: Dr. Werner H. Kirsten, chairman; EugeneGoldwasser, Ph.D.; and Dr. Janet Rowley.CTP-Phosphatidic Acid Cytidyl Transferase fromSaccharomyces Cerevisiae, Partial Purification,Characterization and Kinetic BehaviorGeorge BelendiukSponsor: Dr. Godfrey S. GetzDiscussant: John Westley, Ph.D.Phosphatidic cytidyl transferase (CTP) is a branch pointenzyme in the biosynthesis of phospholipids, whichcatalyzes the formation of CDP-diglyceride from CTPand phosphatidic acid. CDP-diglyceride in tum serves asa substrate in the biosynthesis of phosphatidyl inositol,phosphatidyl serine and cardiolipin. Hence the regulationfor CDP-diglyceride may playa central role in the regula­tion of membrane phospholipid biosynthesis.CTP-phosphatidic acid cytidyl transferase was sol­ubilized from crude mitochondrial membranes by usingdigitonin. It was further purified by chromatography onDEAE-Sephadex, QAE-Sephadex and Sepharose 6Bcolumns. At this stage the enzyme, enriched 550-foldover crude cell homogenate, remains associated withphospholipid and has an estimated approximate molecu­lar weight of 400,000 on the basis of gel filtrationchromatography. SDS polyacrylamide gel elec­trophoresis of the 550-fold enriched enzyme yielded twomajor protein bands having molecular weights of 45,000and 19,000 daltons. The enzyme exhibits an absolute de­pendence on Triton X- 100, a sharp Mg++ dependencewith an optimum at 20 mM and a pH optimum of 6.5 foractivity.Kinetic analysis of the behavior of CTP-phosphatidicacid cytidyl transferase was performed at three differentstages of its purification. Initial analysis of the datayielded biphasic behavior in double reciprocal plots, withrespect to both substances. Hill plots of the data in­dicated the presence of negative cooperativity.A detailed analysis of the kinetic behavior was per­formed on the enzyme purified 550-fold. The data suggesta mechanism involving two distinct cycles of catalysisresponsive to homotropic modifications with differentaffinities for both substrates. Further analysis of the kine­tic behavior in the presence of inhibitors (dCTP and PPi)yielded a reaction order for the entrance of substrates anddeparture of products from the reaction cycles.Identification of a VHl SubSubgroup of Human Heavy ChainsErnest BrahnSponsor: Dr. John E. HopperDiscussant: Dr. Heinz KohlerThe variable region of human immunoglobulin heavychains (V H) may be classified into three distinct sub­groups according to their shared amino acid sequencehomologies. The V H subgroup differences are usually as­cribed to separately encoding germ line genes. The heavychain sequences most often reported in the literature aremembers of the Vui» subgroup since they characteristi­cally have an unblocked N-terminus, greatly facilitatingamino acid sequence analysis.A patient (Tho) was identified whose serum proteinelectrophoresis revealed two distinct paraproteins of theIgGK class. The electrophoretically slower Tho.s, IgG wasisolated and an amino acid sequence of the first 27N-terminal heavy chain residues revealed an unblockedVHl subgroup.The only prior unblocked VHl immunoglobulins re­ported are protein (Ben), whose 15-residue sequence isinsufficient for comparison, and protein (Bro). The lattershares 25 of the 27 N-terminal residues of Thorsi. BothTho and Bro VH sequences possess a unique amino acidsubstitution at positions 16, 18, and 24 which, in conjunc­tion with the unblocked N-terminus, delineate a sub­subgroup of VHI.Preliminary analysis of the faster Thorn protein in­dicates idiotypic determinants highly similar or identicalto the Tho.s.. In addition, the electrophoretic mobility ofthe Tho heavy chains corresponds to the respective par­ent Tho(FI paraproteins. This suggests that the structuraldifferences in the Tho heavy chains are more distal toposition 27 and probably reside outside the hypervariablesegments (i.e., idiotypic region).The addition of the Tho sequence to the previouslypublished VHl proteins supports the ala-glu-val triplet atpositions 9-11 as a subgroup-specific sequence. The exis­tence of an unblocked VHl sub-subgroup, however, pre­cludes the automatic assignment of any free N-terminusto Vui» and emphasizes the need to extend the analysisthrough the subgroup-specific region.Renal Regeneration AfterAcute Tubular NecrosisRichard C. DoddSponsor: Dr. F. Gary TobackDiscussant: Dr. Godfrey S. GetzPhospholipid and protein synthesis were studied in re­generating proximal tubular cells of rats during recoveryfrom acute renal failure induced by the administration ofmercuric chloride. The rate of incorporation of 14C_choline into membrane phospholipids and of 14C-leucineand 3H-tyrosine into protein was measured in kidney cor­tical slices from animals at various times after the onsetof acute tubular necrosis. During the course of the syn- drome serum urea nitrogen, body weight, daily food andwater intake, urinary volume, and electrolyte excretionwere monitored.The incorporation of 14C-choline into renal membranephospholipids was increased up to 104 percent, 3H­tyrosine into protein by 109 percent, and 14-C-leucine intoprotein by 80 percent during the experimental syndromeat a time when azotemia was severe and food intake wasmarkedly decreased.To evaluate the capacity of amino acids to enhancerenal protein metabolism during the course of acute renalfailure, animals were infused intravenously for 18 hoursprior to study. The concentrations ofleucine and tyrosinein renal cortical tissue, were raised to or above normalvalues by the amino acid infusion. In addition, the rate of3H-tyrosine and 14C-leucine incorporation into proteinwas increased in the rats infused with amino acid com­pared to untreated animals with the syndrome. Aminoacids have previously been shown to enhance phos­pholipid synthesis during renal regeneration.The results indicate that enhanced synthesis ofcholine-containing phospholipids and of proteins occursin regenerating renal cells despite marked systemiccatabolism and renal functional insufficiency. The capa­city of amino acid infusions to increase phospholipid andprotein synthesis during this syndrome suggests that thismode of therapy may be beneficial in speeding recoveryfrom acute renal failure in man.Albert S. Leveille (left), Mrs. Leveille and Dean Robert B. Uretz.Prospective Evaluation of MultipleEndocrine Systems in Patients withSlipped Capital Femoral EpiphysisRobert W. GeistSponsor: Dr. Phillip G. SpiegelDiscussant: Dr. Barry H. RichTwenty-five years following its introduction, the endo­crine basis for slipped capital femoral epiphysis (SCFE)remains unsupported by strong clinical evidence. Iso­lated case reports of endocrinopathies associated withSCFE comprise the bulk of the literature on this subject.This report provides the first prospective evaluation of13(Left to right) David A. Rawling, Richard Uhlmann, and KennethKampman.multiple endocrine systems III patients presenting withSCFE.This study involved 27 patients seen consecutively atThe University of Chicago Hospitals and Clinics with thediagnosis of slipped capital femoral epiphysis betweenApril 1974 and February 1978. Males comprised 63 per­cent of the series and presented at mean age 13.9 years(range 11.5-18.5 years), while females presented atmean age 11.4 years (range 9.25-13.75 years). Eighty­four percent of the patients were above the 90th percen­tile for weight (52 percent were greater than the 97thpercentile) and 41 percent exceeded the 90th percentilefor height.The left hip was affected in 37 percent, the right hip in33 percent, and 30 percent were bilateral. Bone age wasabnormal in 7 percent. No patients exhibitedhypothyroidism by total thyroxine (TT4), free thyroxineindex (FTI), or triiodothyronine (T3), and one patient (5percent) was hyperthyroid. No abnormalities were dem­onstrated in serum cortisol or estrogen levels. De­hydroepiandrosterone sulfate (DHAS) levels, indicativeof adrenal maturity, were abnormally low in 5 percent ofpatients and testosterone was low in 29 percent of malepatients.Following an oral dose of L-dihydroxyphenylalanine(L-DOPA), a provocative test which measures pituitaryreserve for growth hormone secretion, 11 percent of pa­tients failed to respond. Eighty-four percent respondednormally, and one patient responded with excess growthhormone. The gonadotropic hormone releasing hormone(GNRH) test was also performed, in which folliclestimulating hormone (FSH) and leutenizing hormone(LH) are released in response to an intravenous bolus ofGNRH. This test is an indicator of maturity of thehypothalamic-pituitary-gonadal axis. Thirty-eight per­cent of males and 13 percent of females tested demon­strated hypersecretion of FSH and/or LH, indicatingsome degree of gonadal immaturity. Altogether, 47 per­cent of male patients and 10 percent of females exhibitedsome evidence of hypogonadism.14 This study demonstrates biochemical evidence ofhypogonadism in a large proportion of male patients withSCFE. Since sex hormones are known to promote epiphy­seal maturation and increase its shear strength, de­ficiency of sex hormones, it has been postulated, pre­dispose an individual toward SCFE. It may arise by in­creasing the period of epiphyseal immaturity.Hypogonadal epiphyseal immaturity could, in combina­tion with obesity (i.e., an adverse biochemical factor),account in part for the etiology of SCFE.Gastric Inhibitory Polypeptide (GIP)Secretion in Juvenile-Onset DiabetesEdward F. GibbonsSponsor: Dr. Arthur H. RubensteinDissussant : Dr. Irwin H. RosenbergInsulin secretion in normal subjects is substantiallygreater in response to oral rather than intravenous ad­ministration of glucose. Recent studies have identifiedthe 41-amino acid gastric inhibitory polypeptide (GIP) asthe probable intestinal mediator of this augmented insulinresponse. Examination of GIP secretion in obesematurity-onset diabetics has demonstrated supernormalGIP response to oral glucose and suggested a lack ofnegative feedback by insulin in these subjects.The present studies were designed to investigate GIPsecretion in non-obese insulin-deficient subjects, definedaccording to their clinical course and verified by low toabsent C-peptide immunoreactivity in their sera. Eightnormal and 11 diabetic subjects were given 1 grn/kg glu­cose orally after an overnight fast. The diabetic subjectsshowed a significantly lower (p < 0.05) GIP secretory re­sponse compared to normal subjects. An insulin infusionof 0.1 units porcine insulin per kg of body weight did notinhibit GIP secretion in either diabetic or normal sub­jects.Subnormal GIP secretion in insulin-dependentjuvenile-onset diabetics may be secondary to their insulindeficiency, and may likewise reflect the general hormonalmismatching which distinguishes the juvenile-onset di­abetic from the maturity-onset diabetic.Translation in vivo and in vitro of RatPlasma Apolipoprotein-like ProteinsRick HaySponsor: Dr. Godfrey S. GetzDiscussant: Dr. Jayme BorensztajnAntibodies raised against rat plasma ,B-lipoprotein and apurified fraction of arginine-rich peptides (ARP) werelabelled with N a 1251 and were shown to bind to polyrib­osomes isolated from rat liver. Enriched antibody frac­tions subsequently obtained by selective affinitychromatography exhibited increased levels of binding topolysomes. Anti-d-Iipoprotein immunoreactivity wasfurther resolved into anti-ARP and anti-apolipoprotein Bcomponents, each reactive with a distinct polysomepopulation. Binding was specific for rat polysomes andwas directed toward nascent polypeptide chains.About two percent of normal rat liver polysomes wererecovered by indirect immunoprecipitation with anti-,B­lipoprotein. Ribonucleic acid (RNA) extracted from thisimmunoprecipitate contained species with polyadenylate(polyt A) sequences characteristic of eukaryotic mes­senger RNA (mRNA). These species, purified by affinitychromatography on polyuridylate-Sepharose, stimulatedthe in vitro synthesis of immunoprecipitableapolipoprotein-like proteins by about 17-fold when com­pared to unfractionated rat liver mRNA. The average sizeof this enriched mRNA was about 600,000 daltons, with apoly(A) content of about 140 nucleotides and sufficientcoding capacity for the biosynthesis of 50,-55,000 daltonpolypeptides.Most of the in vitro translation products precipitated bypurified anti-ARP migrated identically on polyacrylamidegel electrophoresis with unlabeled purified ARP. Prod­ucts precipitated by anti-d-lipoprotein included bothARP-like protein and higher molecular weight specieswhose identity has not been determined.Delayed Clearance of Morphine from theCirculation of Rabbits with Morphine-6-Hemisuccinate Bovine Serum AlbuminJeffrey H. HillSponsor: Dr. Richard M. RothbergDiscussant: Dr. Frank W. FitchMorphine clearance from the circulation of normal rab­bits and rabbits with circulating anti-morphine antibodywas studied. Individual animals were injected with 14Ctrace-labeled morphine in saline (6 mg morphine/kg bodyweight). The rabbits were bled at various times after morphine injection and the amount of morphine presentin the serum at each time interval was determined.Morphine could be detected in the serum of normalanimals for one week following injection and up to twelveweeks following injection in at least one animal with anti­bodies to morphine. The rate of morphine clearance innormal animals immunized to morphine-6-hemisuccinatebovine serum albumin was not significantly different fromnormal during the first 4 hours after morphine injection.However, by 24 hours after injection, the rate of mor­phine clearance in morphine-6-hemisuccinate bovineserum albumin-immunized animals was significantlyslower than in normal animals.The amount of morphine present in the sera of therabbits 24 hours after injection was related to theantigen-binding capacity and independent of antibody av­idity. However, the rate of morphine clearance at timesgreater than 24 hours after injection was related to theaverage antibody avidity and not related to the antigen­binding capacity. The retension of hapten in the circula­tion by antibody may represent an in vivo mechanism ofdefense against small toxic molecules.Molecular Aspects of theInitiation of ErythropoiesisGeorge InanaSponsor: Eugene Goldwasser, Ph.D.Discussant: Dr. Martin GrossThe early effect of erythropoietin (epo), the primary in­ducer of erythroid differentiation in mammals, is on thestimulation of nuclear RNA synthesis. Exactly how theinteraction of epo and its target cell leads to stimulationof transcription is not known. Whether epo enters the(Left to right) Ernest Brahn, Stuart Shulruff, Philip M. Laughlin, and Richard C. Dodd.15target cell has not been answered due to unavailability ofbiologically-active labeled epo.It has been shown that bead-linked epo can affecttarget cells and that protein receptors for epo are presenton the outer surface of those cells. Both findings suggestthat epo may act at the outer cell surface. Previously, acytoplasmic protein factor that seemed to be the mediatorof epo action had been isolated from marrow cells in­cubated with epo. This factor, called marrow cytoplasmicfactor (MCF), had no effect on transcription by wholecells or DNA synthesis by nuclei, but could stimulatetranscription by isolated nuclei. We have furtherexamined the stimulation of transcription by isolated nuc­lei. We have examined the stimulation oftranscription byFrank A. Ventimiglia (left) and Or. Werner Kirsten.epo, and have been able to stabilize and study the MCFmode of action.Nuclei isolated from marrow cells incubated with eposhowed stimulation of transcri ption at 15 min., 1 hr., andat 10.5 hr. after epo addition. Template availability andRN A polymerase activities of nuclei were measured byaddition of excess RNA polymerase (with or withouto-amanitin) or DNA to sonically disrupted nuclei. Bothpolymerase and template activities were found to bestimulated by epo at 1 and 2 hr. The maximum stimula­tion of RN A polymerase at 1 hr. was primarily the effecton RNA polymerase II.Stabilization ofMCF was effected with calcium (4 rn M)and phenylmethanesuifonylftuoride. MCF activity wasshown not to be due to an effect of nucleotidase, hemog­lobin, DNA, or RNA polymerase, all of which were con­tained in the cytoplasmic preparations and could haveaffected transcription by isolated nuclei. Ultrogel AcA 44filtration of MCF produced a highly active fraction ofMCF at the leading edge of excluded material peak.MCF was shown to stimulate both RNA polymeraseand template activities in marrow nuclei and also in liverand kidney nuclei. Both RNA polymerase I and II were16 stimulated approximately equally by MCF, in contrast toepo stimulation. MCF could not directly stimulate theactivity of solubilized RNA polymerase from marrow orliver nuclei.Our data provide additional support for the hypothesisof epo action through MCF in the target cell, and give usa preliminary view of the early molecular events in theinduction of erythroid differentiation.Sublethal Permanent Myocardial InjuryFollowing Prolonged Cardioplegic Arrest:Long-Term Morphologic StudiesKenneth KampmanSponsor: Dr. John J. LambertiDiscussant: Dr. Robert L. ReplogleControversy exists regarding the optimal method of pre­serving myocardial structure and function during cardiacsurgery. Five groups of mongrel dogs were subjected to90-120 min. of cardiopulmonary bypass. In Group I theheart was beating but nonworking (BNW) for 60 min. Ingroup II the heart was spontaneously fibrillating withcoronary perfusion (VF) for 60 min. Group III had theaorta cross-clamped for 70 min. while the heart wasbathed in cold (4° c) Lactated Ringers for topical cardiachypothermia (TCH). In Groups IV and V the aorta wascross-clamped for 60 and 90 min. respectively and phar­macologic arrest (PC A) was accomplished by injecting amagnesium-procaine cardioplegic solution into the aorticroot (TCH was added).Seven weeks after operation the survivors were anes­thetized, maximum LV dP/dt, CO, L VEDP, L VP andEKG were measured, and the hearts were fixed by perfu­sion with glutaraldehyde. Transmural samples weretaken from four standard LV sites and examined by lightmicroscopy, with the following results:GROUP Cross-ClampTime %SurvivalIIIIIIIVV 6/66/86/146/66/9 (100%)( 75%)( 44%)(100%)( 67%)60 min.60 min.90 min.MyocardialProtection # LV SectionsWith Injury # HeartsWith InjuryBNWVFTCHPCA, TCHPCA, TCH 1/24 (4%)4/24 (16%)4/24 (16%)3/24 (12%)17/24 (71%) 1/6 (16%)2/6 (33%)2/6 (33%)1/6 (16%)6/6 (100%)All operative death occurred within 24 hr. of the arrestinterval and were secondary to cardiorespiratory compli­cations. The extent of myocardial damage varied fromisolated, punctate subendocardial scars (0.5-1.0 mm. indiameter) to severe, diffuse subendocardial scarring seenin two hearts in Group V. All animals were hemodynami­cally normal at sacrifice.We conclude that PCA combined with TCH providessatisfactory protection from long-term myocardial injuryif the ischemic interval is 60 min. or less. Ischemic inter­vals longer than 60 min. may be complicated by perma­nent myocardial damage even if PCA and TCH are em­ployed.Acute Mortality and Morbidity in Transmuraland Nontransmural Myocardial InfarctionPhilip M. LaughlinSponsor: Dr. Jafar Al-SadirDiscussant: Dr. William FoxA major controversy exists in the clinical literature as tothe natural history of acute non transmural myocardialinfarction (NTMI) as compared to acute transmuralmyocardial infarction (TMI). The clinical andhemodynamic data of 200 consecutive patients admittedto the Coronary Care Unit of The University of ChicagoMedical Center were reviewed. Of these, 109 had a TMIas defined by history, typical cardiac enzyme elevations,and the development of new Q waves with evolving STsegment changes. Twenty-nine had an NTMI as definedby history, typical enzyme changes, and evolving STsegment depression in the absence of new or evolvingQRS abnormalities. The two groups had similar composi­tion with respect to age, race, and sex.The incidence of prior angina (18/29 NTMI, 64/109TMI) and of previous MI (15/29 NTMI, 50/109 TMI) wasthe same in both groups, as was the incidence of in­hospital arrhythmias (13/29 NTMI, 54/109 TMI). Meanenzyme elevation was significantly higher in TMI(CPK = 124 IU, LDH = 155 IU) than in NTMI (CPK =431 IU, LDH = 93 IU). The two groups did not differ withrespect to physiologic status as measured clinically (Kil­lip classes I-IV, admission BP) and hemodynamically(pulmonary arterial pressure, left ventricular filling pres­sure, cardiac index, stroke volume).Although the in-hospital mortality was lower in NTMI(2/29,6.9 percent) than in TMI (17/109,15.6 percent), thisdifference was not statistically significant. It appears thatacute non transmural MI represents as serious a clinicalevent as the classical acute transmural MI and requires asvigorous surveillance and treatment.Cyclopropenoid Stimulation ofArterial Smooth Muscle CellsAlbert S. LeveilleSponsor: Dr. Robert W. WisslerDiscussant: Dr. Katti Fischer-DzogaCyclopropenoid compounds are naturally occuring CI9long chain fatty acids which have been shown to exertmany adverse affects in animals, including increasedmitosis in and necrosis of rat hepatocytes, and elevation of serum cholesterol and enhancement of atherosclerosisin hens. The cyclopropenoid compound most often im­plicated is sterculic acid, which in its triglyceride formcomprises 50 percent of the oil from Sterculia foetidaseeds, and 0.5 percent of unrefined cottonseed oil. To seeif sterculic acid triglyceride has a direct effect on smoothmuscle proliferation, tissue culture experiments wereperformed.In stationary primary rabbit aortic smooth muscle cellcultures outgrowth diameters of explants increased whentreated with very small quantities of sterculic acid trig­lyceride. This response was similar to the increase incultures treated with hyperlipemic serum (which hasbeen shown to stimulate smooth muscle cell proliferationin previous studies in this laboratory.) Using autoradiog­raphy following a (3H) thymidine pulse, more labeledcells were found in the sterculic acid triglyceride treatedgroups than in controls, but not as many as in the grouptreated with hyperlipemic serum.In a second experiment, using trypsinized, subculturedrabbit smooth muscle cells, sterculic acid triglyceride re­sulted in an increased incorporation of eH) thymidinemeasured as radioactivity per milligram of protein.Thus, two methods commonly used to measure cellproliferation produced confirming evidence of increasedcell proliferation at statistically significant levels(p < 0.05). We concluded that cyclopropenoid trig­lycerides present in small amounts (less than 0.002 mg.per ml. of medium) can cause proliferation of arterialsmooth muscle cells, which is an integral element in thedevelopment of atherosclerosis.Peritoneal Reaction to Simulated SurgicalInsult Measured by Neovascularizationand Collagen DepositionKeith s. N aunheimSponsor: Dr. Robert L. ReplogleDiscussant: Dr. Donald J. FergusonIntestinal adhesions are a frequent complication of ab­dominal surgery. The stimulus for adhesion formation isdamage to the intraperitoneal tissue. This causes localinflammation which evolves into a reparative process andproduces a fibrous band with potentially grave conse­quences.Peritoneal injury and inflammation result from manytypes of operative insults including direct physicaltrauma, dehydration of intra-abdominal tissues and intra­peritoneal bacterial contamination.Fifty Sprague Dawley rats were randomly divided intofive groups. One group of ten rats served as the control,undergoing a laparotomy with careful attention paid tosterile technique, proper hemostasis and continual irriga­tion of the bowel to prevent drying. The other four groupsunderwent laparotomies simulating four different opera­tive insults: bacterial contamination, bacterial con­tamination with antibiotic prophylaxis, drying of thetisues, and intra-abdominal bleeding.The peritoneal inflammatory and reparative responseswere quantitated by measuring the amount of neovas-17cularization and collagen deposition in the mesenteric tis­sues. Both the "contaminated" group and the "dehydra­tion" group showed highly significant increases (p > .001)in the extent of neovascularization and in the amount ofcollagen deposition. The "bleeding" group also showed ahighly significant increase in the amount of collagen de­position, but no difference with regard to new vasculargrowth.The experiments thus suggest that of the four differentvarieties of insults, bacterial contamination and dehydra­tion produce the most active inflammatory response andthe most vigorous repair. It would seem that of all theinsults tested, these two would be most likely to pre­dispose a patient to the formation of intra-abdominaladhesions. Also it is interesting to note that preoperativeantibiotic prophylaxis (penicillin) seemed to have a pro­tective effect by preventing significantly increased in­flammation and repair as quantitated with our method.(Left to right) Edward F. Gibbons, Rick V. Hay, and Richard C. Richter.Natural Infection of Humans with OncogenicRNA Viruses of Higher PrimatesEdward V. ProchownikSponsor: Dr. Werner H. KirstenDiscussant: Dr. Elliot KieffThe type C RNA viruses have long been known to causeleukemias, lymphomas and sarcomas in many animalspecies. These observations have stimulated intense in­vestigation aimed at establishing a viral etiology ofhuman cancer. In 1975 we observed the release of type Cviruses (HEL-12) from a strain of normal human em­bryonic lung fibroblasts. Immunologic characterization ofthe major virion structural protein and of the virion en­zyme RNA-dependent DNA polymerase (reverse trans-18 criptase) established that HEL-12 virus was in­distinguishable from simian sarcoma virus (SiSV), aknown cause of fibrosarcomas in the wooley monkey.Infection of cells by type C viruses results in the syn­thesis of a reverse transcriptase-rnediated complemen­tary DNA copy of the viral RNA. The insertion of thisDNA provirus into the host genome stabilizes the viralinformation and allows daughter cells to inherit themalignant phenotype in a stable fashion. DNA was there­fore extracted from fresh post-mortem tissues of patientswith various mesenchymal tumors and was hybridizedwith 1251-labeled HEL-12 RNA.DNA from tissues of 2 of 9 patients formed double­stranded structures with the 1251-RNA. The DNA se­quences detected were closely related to those found incultured cells deliberately infected with SiSV. Further,investigations with purified IgG from 86 patients withleukemias or lymphomas or from matched controlsshowed that 49 percent of the former group and 26 per­cent of controls had circulating antibody which inhibitedprimate virus reverse transcriptases. Enzymes of avian,murine or feline viruses were not inhibited.These results indicate that known oncogenic viruses ofsubhuman primates are capable of crossing species bar­riers and introducing into human cells exogenous geneticmaterial of established neoplastic potential. This non­Mendelian mode of inheritance and the host's subsequentimmune response may be pertinent factors in the etiologyof hematologic maligancy.Electrophysiological Effects of Imipramineon Cardiac Purkinje FibersDavid A. RawlingSponsor: Dr. Harry A. FozzardDiscussant: Dr. Morton ArnsdorfImipramine produces ECG changes in patients. Further,many overdose victims develop cardiac conduction dis­turbances and die of cardiac arrhythmias. Given theseobservations I wondered if these phenomena could be theresult of a direct action of imipramine on cardiac tissue,or secondary to its known parasympatholytic and sym­pathomimetic effects. Using standard electrophysiologi­cal techniques the dose-response relationship of im­ipramine and the membrane excitability properties ofcardiac Purkinje fibers were examined.Intracellular current injection was used. Imipramine ata concentration of 1000 ng./ml. decreased action potentialduration by 44 percent, (dV/dt)max by 46 percent, andconduction velocity by 27 percent. In addition, mem­brane responsiveness experiments showed a reduction in(dV Idt)max for all membrane voltages (V m), a decrease inthe lowest V m at which the fiber could be stimulated, andslowing of the time constant of recovery of the rapidinward sodium current.Some of these properties of imipramine are seen withvarious antiarrhythmic agents, and, indeed, imipraminehas been reported to have antiarrhythmic activity. Infact, imipramine has often been compared to quinidine,although unlike quinidine, imipramine shortens the action(Left to right) JeffreyH. Hill, Edward V.Prochownik, Keith S.Naunheim, andCarol A. Westbrook.potential duration. Further, its electrophysiological ef­fects are such that it may be the prototype for a new classof antiarrhythmic agents.In conclusion, imipramine has been shown to have pro­found effects upon cardiac Purkinje fibers. These findingsaccount for many of the ECG changes and conductiondisturbances seen in patients who have taken this drug.Finally, it may represent a new class of antiarrhythmicagent.Pyruvate Flux Across the IsolatedHuman Erythrocyte MembraneWard R. RiceSponsor: Dr. Theodore L. SteckDiscussant: Dr. Robert GunnThe kinetics of pyruvate flux across isolated human ery­throcyte membranes were studied by a simple and pre­cise spectrophotometric method: following the oxidationof N ADH via lactate dehydrogenase trapped within re­sealed ghosts, right-side-out vesicles and inside-out vesi­cles. The initial rate of pyruvate entry was linear in allcases.The flux in these three systems was characterized by: asigmoid dependence of velocity on pyruvate concentra­tion in the absence of other electrolytes; a shift to hyper­bolic kinetics and stimulation of rate in the presence oflow levels of other ions; inhibition by high levels ofchloride, bicarbonate, thiocyanate and salicylate; stimu­lation by oppositely-directed gradients of transportableanions; and inhibition by known non-competitive in­hibitors of anion flux. Kinetic parameters determined forflux from the cytoplasmic and extracellular surfaces re­vealed asymmetry.Perturbations of band 3 (the purported anion transport protein) had varying effects. Incubation of the cytoplas­mic surface of membranes with o-phenanthroline/Cuxfr,mixtures, a treatment known to cross-link band 3, in­creased both the pyruvate concentration at half-maximalvelocity (Ki) and the maximal velocity (Vi) when flux wasexamined in the opposite direction. Two glycolytic en­zymes, aldolase and glyceraldehyde 3-phosphate de­hydrogenase, which bind specifically to band 3, had noeffect on pyruvate flux in either direction. Proteolyticdigestion which removes the 40,000 dalton cytoplasmicsurface domain of the 90,000 dalton band 3 polypeptide,produced an insignificant change in flux.My findings are compatible with the hypothesis thatpyruvate transport in the human erythrocyte is mediatedby a protein which spans the membrane in a fixed andasymmetric fashion and changes its state during translo­cation. All of my data are compatible with band 3 beingthis protein.Identification of a Familial SerumLipoprotein Abnormality in aPatient with HyperlipoproteinemiaRichard C. RichterSponsor: Dr. Godfrey S. GetzDiscussant: Dr. Arthur RubinsteinSerum lipoprotein apoproteins perform important func­tions not only as structural components of lipoproteins,but also as modulators of their metabolism. One suchapoprotein, apo C-II, is a member of the apo C class oflow molecular weight apoproteins found in serum verylow density lipoprotein (VLDL).The VLDL of a female patient with diabetes mellitusand a profound hypertriglyceridemia was studied byscanning the stained polyacrylamide gel electrophoro-19grams of apoproteins isolated by ultracentrifugation anddelipidation with tetramethyl urea. The relative pro­portions of apo C species present in VLDL from theindex patient and several first degree relatives were com­pared with those from populations of healthy males,healthy females, and females with diabetes mellitus.The percentage of total apo C as apo C-II in VLDLfrom this patient and two of her sisters was in each caseless than half of the mean value for each of the controlgroups. There were no significant differences in the apo Cdistribution among the three control groups. The lowpercentage of apo C-II in VLDL from the index patientwas independent of the wide fluctuations in her serumtriglyceride level which occurred during the period ofstudy.Apo C-II is a potent activator of lipoprotein lipase, atriglyceride lipase found in many tissues which plays anessential role in the peripheral catabolism of triglyceriderich VLDL. The relative decrement in apo C-II found inthis patient and several normolipemic, normoglycermicrelatives suggests that hypertriglyceridemic states can insome cases result from a genetically determined im­balance in the apoprotein complement of VLDL. Theperipheral clearance of triglyceride from the blood of thispatient with diabetes mellitus may be impaired due toinadequate activation oflipoprotein lipase by this unusualIi poprotein.Cardiac Manifestations of InflammatoryBowel Disease: Abnormalitiesof the Electrocardiogramand their Clinical CorrelationsStuart ShulruffSponsor: Dr. Jafar Al-SadirDiscussant: Dr. Joseph B. KirsnerThe extra-intestinal manifestations of inflammatorybowel disease (Crohn's disease and ulcerative colitis) areboth protean and have been well-described in variousreviews and case reports during the past few decades.They include "autoimmune type" manifestations (like ar­thritis, erythema nodosum, and uveitis), problems relatedto bowel pathophysiology (malabsorption, renal stones,etc.), and also problems related to drug treatment, espe­cially from steroids.Poorly defined to date, however, are cardiac manifesta­tions. Only eight case reports of pericarditis have beendescribed. In order to explore and better describe thistopic, we reviewed the electrocardiograms of 255 in­flammatory bowel disease (IBD) patients hospitalized atour institution during 1975 and 1976. For each patientwith abnormal electrocardiograms we reviewed the hos­pital chart for clinical correlations, then classified andinterpreted the results.Sixty-four out of 238 eligible electrocardiograms wereabnormal (27 percent). These were divided into fivecategories. Category I consisted of 13 patients with directpericardial or myocardial involvement. This categorywas further divided into three subcategories: lA, 5 pa­tients with pericarditis; IB, 2 patients with myocarditis;IC, 6 patients with unexplained T wave inversions similar20 to those in lA, possibly representing cases of subclinicalpericarditis. Category I probably represented "autoim­mune type" manifestations of similar etiology to theexamples mentioned above. Subcategory IB was espe­cially significant as it represented 2 young females (19 and21 years old) with life-threatening congestive heart failureas a manifestation of their underlying bowel disease.Category II was composed of 12 patients who had vary­ing ECG signs of right heart strain (right axis deviation,right precordial T wave inversion, Sl Q3 T3 pattern,etc.). This category was also subdivided: IIA, 4 patientswith documented pulmonary emboli; lIB, 4 patients withperioperative ECG changes consistent with pulmonaryemboli plus suspicious clinical courses, but no documen­tation of such; IIC, 4 patients without significant clinicalcorrelation. Category II should be considered a cardiacmanifestation which is secondary to the already well­described increased incidence of venous thrombosis andlife-threatening pulmonary embolism in IBD patients.Category III contained 13 patients with various ECGmanifestations of hypokalemia (average K=3.48 mEq/l).Most of the patients were receiving steroids in relativelylarge doses. However, only one patient had symptomaticarrhythmias secondary to hypokalemia.Category IV was composed of 15 patients with sinustachycardia (average rate 105.6) and 6 patients with sinusbradycardia (average rate 46.3). The large number of pa­tients with sinus tachycardia is thought to reflect a pre­sumed hypermetabolic state present in IBD patients.Category V was a miscellaenous group of 6 patientswith ECG abnormalities of doubtful relevance to theirunderlying bowel disease.In conclusion, the cardiac manifestations of IBD areextensive and varied, stemming from several differentetiologies which are often of extreme clinical relevance.Demography and Disease in the Navajos:The Effects of Modern Medicine in aTechnologically Developing CultureRichard UhlmannSponsor: Odin W. Anderson, Ph.D.Discussant: Dr. David S. FedsonDuring the past three decades the Navajos have under­gone a striking demographic and epidemiologic transitionwhich appears to have been far more affected by accultu­ration to American society and advancing socioeconomicstatus than by vastly improved medical services. Thedemographic transition includes a decline in mortalityfrom a high level, typical of a developing country (16.4deaths per yr.!1000 population), to a present low level(6.8/1000), less than the U.S. (9.211000). A rapid declinein the birth rate from 45 to 32 births per yr.!1000 popula­tion remains higher than the national rate (14.9/1000). Asa result of excess births over deaths, the population hasflourished.The epidemiologic transition has been characterized bya shift to a mortality pattern. Formerly dominated byinfectious diseases, the mortality pattern is now led bypsychosocial diseases, particularly accidental deathsamong males. A high male to female mortality ratio hasresulted and may be the major force producing a pre­ponderance of females and a stable age distribution whichhas remained young despite substantial declines in infantmortality.The factors which appear most related to the mortalitydecline are socioeconomic improvements, notably in nu­trition, sanitation, hygiene, and housing. Medical ser­vices, which have become comparable to other ruralareas of the U.S. in scope and quality, have had minordemographic and epidemiologic impact on the Navajos.The introduction of birth control technology is tempor­ally correlated to the decline in the birth rate. Ecologicalpressures resulting from decreased infant mortality andincreased population density may have contributed tothis decline.As the effects of medical services are limited by cul­tural acceptance, the experience of the Navajos illus­trates that an interdisciplinary approach to health care isjudicious.The role of modem medicine as a demographic force ina technologically developing society appears to be of farless importance than cultural and socioeconomic status.Accordingly, the goals of such health care programs needto be carefully defined, particularly in terms of meetingfelt needs and in terms of medicine's role as both a prod­uct and a catalyst of acculturation.Exhibitory Effect of Autologous Serumon Circulating Lymphocyte Responses inPatients with Chronic Ulcerative ColitisFrank A. VentimigliaSponsor: Dr. Sumner C. KraftDiscussant: Dr. Richard M. RothbergPatients with ulcerative colitis have shown normal orsuppressed cell-mediated immune responses using in vivoor in vitro techniques. We investigated the possible sup­pressive role of serum factors on the in vitro responses ofcirculating lymphocytes from patients with chronic ul­cerative colitis (CUC). Lymphocytes from 45 patientswith inactive CUC, 8 patients with Crohn's disease (CD)and 34 healthy hospital personnel were incubated inEagle's medium with 15 percent autologous serum or 15percent pooled normal human serum (NHS) in the pres­ence of either saline or optimal amounts ofphytohemagglutinin (PHA), Candida antigen orstreptokinase/streptodornase (Sk/Sd). DNA synthesiswas measured as 3H-thymidine incorporation (dpm).There were no significant differences between thelymphocyte responses of the patients and the healthycontrol subjects to PHA or Sk/Sd using either autologousserum or NHS. The response of lymphocytes from pa­tients with CUC to Candida was significantly lower inautologous serum than in NHS (p < .001). Variations inthe unstimulated dpm did not account for this effect.Lymphocytes from the healthy controls showed no sig­nificant differences in Candida responses in either au­tologous serum or NHS.To test for inhibitory factors, in contrast to the possible lack of stimulatory factors, normal lymphocytes werecultured in a mixture of patient's serum and NHS, each inconcentrations of 15 percent. In this combined system,serum from 3 patients with CUC whose lymphocytes hadpreviously exhibited very low responses to Candida in anDr. Sumner C. Kraft (,55) talks with Dr. Charles McCartney (,43) at thereception following the Senior Scientific Session.Ward R. RiceSenior Scientific Session WinnersTwo awards were presented to students fortheir exceptional presentations at the SeniorScientific Session. They received their awardsat the Medical Alumni dinner June 8. TheMedical Alumni Prize for the best oral presen­tation was awarded to Carol Ann Westbrook,who is taking her residency in internalmedicine at The University of Chicago Hospi­tals. The Catherine Dobson Prize for the bestoral presentation by a non-Ph.D. student wasawarded to Richard C. Dodd, who is pursuingan internal medicine residency at NorthCarolina Memorial Hospital in Chapel Hill.21autologous system also inhibited (> 7S percent) the re­sponses to Candida of normal lymphocytes. The effect ofthis serum factor may not be disease specific since lowerlymphocyte responses to Candida also were observed inCD in the presence of autologous serum (p < .OS).Although the clinical significance of the inhibition oflymphocyte reactivity to Candida by autologous serumremains uncertain, the Candida system may be a sensi­tive way to demonstrate abnormalities m serum­lymphocyte-antigen interactions.Prostaglandin Metabolismin the Human PlacentaCarol A. WestbrookSponsor: Dr. Joseph J. JarabakDiscussant: Josef Fried, Ph.D.Prostaglandins are naturally occurring acidic lipids whichproduce a variety of physiologic effects. They can inducecontraction of the pregnant uterus and there is much evi­dence to suggest that they play an important role in sev­eral other aspects of pregnancy as well. This investiga­tion was undertaken to provide insight into the biologicfunction of these compounds by studying theirmetabolism in the human term placenta. Enzymes in­volved in prostaglandin metabolism were identified, pur­ified, and characterized.The results of this investigation indicate that there areseveral pathways available for prostaglandin metabolismin this tissue. One pathway which inactivates pros­taglandins of the E and F series is initiated by an NAD­requiring IS-dehydrogenase. The second step in thispathway is catalyzed by a l S-ketoprostaglandin .113 re­ductase. Studies suggest that this step is rate-limiting andirreversible, but there is no evidence for regulatory con­trol.An alternative pathway, initiated by an NADP­dependent lS-dehydrogenase,was also identified. As theE and F prostaglandins are poor substrates for this de­hydrogenase, it may function to inactivate other knownprostaglandins, such as PGD, or some as-yet-unidentifiedcompound. This enzyme also contains 9-ketoreductaseactivity, and can thus reversibly convert PGE to PGF.Since these two prostaglandins often have opposing ef­fects on the same tissue, this enzyme can serve to mod­ulate these effects in the placenta.Disc-gel electrophoresis revealed that the activity ofthe NADP-dependent dehydrogenase exists as two majorand one or more minor isozymes. Furthermore, crudeplacental homogenates contain a substance which in­hibits both the 9-ketoreductase and IS-dehydrogenase ac­tivity, evidencing regulatory control of the NADP-linkedsystem. Although the physiologic function of thisalternative pathway is not yet well understood, many ofits properties are shared with an analogous system ofprostaglandin metabolism in the kidney which is involvedin mediating renal blood flow, in renin-angiotensin re­lease, and in the regulation of blood pressure. Thissuggests that the NADP-linked system may have a simi­lar physiologic role in the human placenta.22 George InanaRobert W. GeistGeorge 8e/endiukResidency Assignments for 1978One hundred and seven senior medical students weregraduated this year and all but two participated in the1978 National Residency Matching Program (NRMP).One of the two exceptions applied for and secured aPediatrics residency in a Canadian hospital; the other, anArmy scholarship recipient, was required to do a first­year residency in an Army hospital.Of the 105 students who participated in the NRMP, twomarried couples secured their appointments prior to theactual matching procedure under special arrangementsfor married couples. Four students interested in InternalMedicine residencies were unmatched in the NRMP, butall were subsequently placed in good teaching hospitals.This year's University of Chicago senior medicalgraduates are pursuing residencies in the various disci­plines as follows:Anesthesiology 1Family Practice 1Internal Medicine 55Obstetrics & Gynecology 1Ophthalmology 1Pathology 8Pediatrics 13Psychiatry 5Radiology 2Surgery 18Orthopedic Surgery 2Total 107HospitalsBarnes H. Group, Mo.Baylor College Affil. H., HoustonBlodgett Memorial H., Mich.Cedars-Sinai Med. Ctr., L.A.Children's Ctr., BostonChildren's H., PhiladelphiaChildren's Memorial H., ChicagoCincinnati General H. (3)Cook County H., ChicagoDuke Univ. Med. Ctr.Good Samaritan H., L.A.H. for Sick Children, Torontolnst. of Pennsylvania H.Johns Hopkins H.L.A. County H./USC Ctr. (2)Letterman Army Med. Ctr., San FranciscoLoyola Univ. Affil. H., ChicagoMaine Med. Ctr.Massachusetts General H.Medical College of Wisconsin Affil.Medical College of Virginia (2)Michael Reese H., Chicago (5)Montefiore H. Ctr., N.Y. (4)Mount Zion H., San Francisco Forty-nine students (46 percent) matched to the hospi­tal of their first choice and 75 students (70 percent)matched to one of their top three choices.Of the 105 NRMP students, 89 (85 percent) receivedappointments in residency programs which filled all oftheir allocated positions on the NRMP. Similarly of the70 different hospital units where our students began theirresidency programs July 1, 59 (84 percent) of these re­sidency programs filled all of their allocated positions inthe NRMP."It is my conviction that the success of our students inthe NRMP can be directly attributed to the excellentcooperative efforts of our students and faculty mem­bers," Dean Joseph Ceithaml asserts. "The Committeeon Residency Placement of Senior Medical Students andits chairman, Dr. Robert Replogle, deserve our gratitudeand commendation for the time and effort they expendedon behalf of our senior medical students."The various departmental sub-committees, and par­ticularly the one in Medicine, since more than half of theclass sought residencies in Internal Medicine, should becommended for their part in counseling the students onchoice of hospitals. The number of first-year residenciesin Internal Medicine available this year was fewer thanthe number of applicants seeking such residencies. Con­sequently, in a year when we had a record number ofstudents seeking Internal Medicine residencies, the com­petition for these places was the keeniest ever," con­cludes the dean.New England Ctr. H.New York Univ. Med. Ctr.North Carolina Medical H. (2)Northwestern U niv. Med. Ctr. (2)Rutgers Affil. H., N.J.Stanford Univ. H. (4)SI. Mary's H., San FranciscoStrong Memorial H. N.Y. (2)The New York H.Tulane Univ. Affil. H.U. of Alabama Med. Ctr.U. of Arizona Affil. Ed. Prog.U. of Calif. H., San Francisco (3)U. of Chicago H. (28)U. of Colorado (6)U. of Illinois Affil. H.U. of Miami Affil. H.U. of Missouri Med. Ctr. (2)U. of Oregon Med. Ctr. (2)U. of Pennsylvania H. (2)U. of Texas Southwestern Affil. H. (3)U. of Washington Affil. H.Vanderbilt Univ, Affil. H.Veterans Admin. H., Hines, Ill.Veterans Admin. H., Long Beach, Calif. (3)23Profile-The 1977 Entering ClassJoseph CeithamlThe medical class which began its medical studies in thefall of 1977, arrived on campus just in time to participatein the 50th Anniversary celebration of the opening of theUniversity Hospitals and Clinics. The entering class of104 students was selected from a total of 4,247 applicants.The class consists of20 women (two married) and 84 men(seven married). Of the married students, one of the malestudents has one child. Eight members of the enteringclass were selected for the Medical Scientist TrainingProgram (MSTP) which normally leads to both the M.D.and Ph.D. degrees in six calendar years. The MSTPtrainees began their studies on campus in the summerquarter of 1977. The other 96 students initiated theirfour-year program leading to the M.D. degree in the au­tumn quarter.Of the entering students, 102 possessed at least a bac­calaureate degree. Three had also received masters de­grees, and two held Ph.D. degrees (one in industrial en­gineering, the other in physics). Included in the class areten students from minority groups, as well as two foreignstudents, both from Japan. See Table I.Although two of the students entered with only threeyears of college preparation and two others had Ph.D.degrees, the vast majority of students in the enteringclass were either 21 or 22 years of age. The youngestmember of the class is a 19-year old who completed hisundergraduate studies in three years. The oldest personin the class is a Ph.D., who was 35 years old when hebegan his medical studies. The average age of the enter­ing class is 22; 95 of the students were 22 years of age oryounger at the time they started their medical studies.Table II lists the 53 different colleges and universitiesrepresented in this year's entering class. As expected,The University of Chicago provided the largest numberof students (17), followed by the University of Illinois atUrbana (11) and then Harvard College (6). Loyola Uni­versity of Chicago, University of Michigan, and North­western University each contributed four students, whilethree each came from Carroll College in Montana, U ni­versity of Illinois Circle Campus and State University ofNew York at Binghamton.Table I II shows the geographical distribution of the104 students by residence. Illinois leads the list with 48,followed by N ew York State with 11, Wisconsin andCalifornia each with 5, and Minnesota with 4. Indiana,Michigan and Missouri contributed 3 each, while 17 otherstates and one foreign country contributed 1 or 2 stu­dents.The entering medical class presents the followingacademic credentials. The average cumulative gradepoint average (GPA) in all college studies was 3.76 on ascale where 4.0 equals A and 3.0 equals B. On the wholethe class performed equally well in both the nonscienceand the science courses in college. On the Medical Col­lege Admissions Test (MCAT) the entering class scored24 higher than any previous entering class. The average totalMCAT score for the class was 651 which falls somewherebetween the 85th and 90th percentile of all applicants toU.S. medical schools last year. This class performed re­markably well in the MCAT sub-test on premedical sci­ences where the average score of the class was 710, rep­resenting the 94th percentile of all applicants to U.S.medical schools last year.The academic disciplines in which the entering stu­dents had majored in college is shown in Table IV. Mostof the students majored in the sciences, specifically inbiology (49 per cent) and chemistry (18 percent). On theother hand, 9 per cent of the class were nonsciencemajors. One fourth of the women entrants had non­science majors in college.The policy of our Committee on Admissions is to eval­uate each applicant on his or her own merits. Therefore,it is not surprising that the family backgrounds of thestudents in the entering class vary greatly. For example,Table I: Entering Medical crass, 1977Entering ApplicantsClassSingle Men 77Married men 7Married men with children (1)Total Men 84 3,263Single women 18Married women 2Married women with children 0Total women 20 984Ph.D.'s 2American Oriental students 4Black students 5Mexican American Student 1Foreign students (Japan) 2Total students 104 4,247seven members of the class came from families whereone or both parents had less than a high school education.At the other end of the spectrum, 69 ofthe students camefrom families where one or both parents are collegegraduates. It is noteworthy that seven students camefrom University of Chicago alumni families, (six of thefathers and four of the mothers); in three of these in­stances both of the parents are alumni. Of the alumnifathers, three are graduates of our medical school andtwo received their M. A. degrees here. Similarly, one ofthe mothers received her M.D. degree from our Univer­sity and another mother received her M.A. degree. Inter­estingly, all ten of the alumni parents attended our under­graduate college.The occupations of the parents of our entering studentsinclude representatives of the professions, industry, bus­iness and labor. Among the fathers are 14 physicians, 8engineers, 6 business executives, 5 teachers, 4 salesmen,4 chemists, and 3 accountants. Also included are twoeach of lawyers, physicists, realtors, railroad super­visors, farmers, ministers and school superintendents.Among the other fathers are a dentist, a barber, a truckdriver, a rabbi and a professor. Three of the fathers areretired and 9 others are deceased.Of the mothers, 45 identified themselves as homemak­ers, while the remainder had additional careers. In this latter group are 16 school teachers, 8 secretaries, 4 salesclerks, 3 registered nurses, 2 physicians, 2 librarians, 2bank tellers, 2 switchboard operators and 2 school coun­selors. Also included amongst the mothers are a lawyer,bookkeeper, technical writer, office clerk, cook, wait­ress, restaurant manager, receptionist, psychologist, re­search associate, commercial artist, accountant.janitress,realtor and factory worker. The mothers of three of theentering students are deceased.The 1977 entering medical class has now completed itsfirst academic year on campus and the class has collec­tively demonstrated that it is a very capable one. Muchhas occurred on our campus since we opened the doors ofour Hospital and Clinics some fifty years ago. Our medi­cal alumni have in the past, and continue now, to makeimportant contributions to society in the fields of patientcare, research, and medical education, and many otherareas. Our current faculty fully expects that the classwhich entered in the fall of 1977 will take its rightful placebeside its illustrious predecessors. We all join in wishingmembers of this class every success in their endeavors.Joseph Ceithaml is Dean of Students in the Division ofBiological Sciences and The Pritzker School of Medicineand Professor in the Department of Biochemistry.Table II: Undergraduate College DistributionUniversity of Arizona (2)Boston University (1)Bowdoin College, Maine (1)University of California at Berkeley (1)University of California at Davis (1)University of California at San Diego (1)Calvin College, Michigan (1)Carleton College, Minnesota (2)Carroll College, Montana (3)Case Western Reserve University (1)Centenary College, Louisiana (1)University of Chicago (17)University of Colorado (1)City University of New York, Brooklyn (1)University of Delaware (1)Harvard College (6)University of Houston (1)University of Illinois, Urbana (11)University of Illinois Circle Campus (3)Illinois Institute of Technology (1)Loyola University, Chicago (4)Marquette University (1)Massachusetts Institute of Technology (1)University of Michigan (4)Michigan State University (1)University of Minnesota (1) University of Missouri (1)New York University (1)University of North Carol ina (1)Northwestern University (4)Notre Dame University (1)University of Pennsylvania (1)Penn State University (1)University of Pittsburgh (1)Purdue University (2)Princeton University (1)Providence College (1)Rensselaer Poly tech Institute (1)University of Rochester (1)SI. Louis University (2)St. Mary's College, Minnesota (1)St. Olaf College, Minnesota (1)Stanford University (2)State University of New York at Binghamton (3)Swarthmore College (1)Tulane University (1)Union College, New York (1)Vanderbi It University (1)University of Virginia (1)Wabash College (1)Washington University (1)University of Wisconsin, Madison (1)Yale University (1)Number of Schools: 5325Table III: Geographic Distribution of Entering Class Table IV: Academic Major DistributionArizona 1 Minnesota 4 Major Men Women TotalCalifornia 5 Mississippi 1 Anthropology 1 0 1Colorado 1 Missouri 3 Art History 0 1 1Connecticut 1 Montana 1 Biochemistry 9 0 9Delaware 1 New York 11 Biology 41 10 51Georgia 2 Ohio 1 Biomedical Engineering 2 0 2Hawaii 1 Pennsylvania 2 Biophysics 1 1 2Idaho 1 Rhode Island 1 Chemistry 16 3 19Illinois 48 South Dakota 1 German 0 1 1Indiana 3 Tennessee 1 Human Behavior 1 1 2Maryland 2 Virginia 2 History 1 0 1Massachusetts 1 Wisconsin 5 Humanities 0 2 2Michigan 3 Japan 2 Human Nutrition 0 1 1Industrial Engineering 1 0 1Mathematics 1 0 1Microbiology 0 1Philosophy 0Preprofessional Studies 4 0 4Psychobiology 1 0 1Physics 2 0 2Number of States: 25 Physiology 0 1Number of ForeignCountries: 1 Totals 84 20 104A Closer Look:8 Students After Year 1The number of first-year students in American medicalschools during the 1977-78 academic year was greaterthan in any previous year. According to an Association ofAmerican Medical Colleges study, 16,136 students wereadmitted to the nation's 120 medical schools in the fall of1977, about twice the number admitted in 1960.The increase in student numbers has not meant a de­cline in competition for entrance, however. Instead thescramble for places in medical school has intensified.This past year's entering class of 104 medical students atThe University of Chicago was selected from an appli­cant pool of 4,247.In these times of heightened interest in and competi­tion for admission to professional schools, what are thestudents like? What are their backgrounds, personalinterests and medical goals?In the following eight interviews members of the enter­ing class talk about themselves and medicine at the endof their first year.Bruce BeutlerBruce Beutler, 20, is spending his summer in an im­munology laboratory in Southern California studyingH-Y antigen. The son of a hematologist who practices atthe City of Hope Hospital, Duarte, California, Bruce is26no stranger to research work. For years he has workedfor investigators in infectious disease, experimental ge­netics, hematology and immunology. Most recently heassisted in research at the University's Marjorie B.Kovler Viral Oncology Laboratories."I first became interested in immunology while work­ing with a cell biologist in California," explains Bruce."Some of the research involved viruses and their role inthe evolution of immunity. This year Bernard Roizman'slectures on virology further interested me and in thespring I was able to take an elective to work in PatriciaSpear's laboratory."Professor Roizman is the chairman of the Committeeon Virology. Professor Spear is an assistant professor onthe Committees of Immunology and Virology. Both aremembers of the Department of Microbiology and aredoing fesearch on Herpes Simplex Virus (HSV), a familyof DNA viruses which infect humans as well as manyanimals.On Tuesdays and Thursdays of spring quarter, Brucewas in the virology lab all day. He infected cells withHSV the evening before, arrived the next morning toharvest them, checked them and then prepared them forcounting that evening. Bruce and his co-workers wereexamining the Fe receptor of infected cells, a proteinwhose unusual ability to bind antibody molecules ispuzzling in purpose. "I have always enjoyed working in laboratories," themedical student remarks, "but I would like to combineresearch with clinical practice. Clinical work gives youideas for research. It inspires methods for solving prob­lems in biology."The Beutler family lives in Arcadia, California, outsideLos Angeles. Though both parents attended the Collegeof The University of Chicago, Bruce and his two brotherswent to the University of California at San Diego, closerto home. His younger sister will start college there thisfall. One brother is now with a computer firm and theother is a doctor who graduated from the University ofChicago Medical School in 1977. Bruce's father, Dr. Er­nest Beutler, is a graduate of the University's MedicalSchool Class of 1950."My father recommended this school," he notes, "andI had also heard elsewhere that The University ofChicago produced more medical scientists than any otherinstitution." Bruce intends to continue making use of theresearch opportunities at the University, though he doesnot plan to get a Ph.D.Outside of the lab, his chief diversion is music, espe­cially of the baroque and classical periods. I attend con­certs as often as I can and listen to a great deal of music athome." Bruce also plays the recorder, which he de­scribes with a smile as "a very easy instrument to learn toplay, yet very rewarding."Clarence BraddockWhen Clarence Braddock, 21, graduates from medicalschool he will be a sailor. Clarence has a Navy schol­arship which covers his medical school expenses in re­turn for a three-year tour of duty as a Navy doctor. Hemay be on land instead of on board ship, but chances arehe will be doing some travelling."There are a couple of advantages to the Navy pro­gram," Clarence explains. "First, you've got ajob whenyou get out of school, and second," he continues, "if youdon't mind going to other places outside the U.S. this isone of the ways to do it without taking time off frommedicine or spending a lot of money. I'll get a chance totravel that I probably wouldn't get otherwise."Travelling seems to be a part of the Braddock familylife. Clarence was born in Philadelphia the third of fourchildren. The family then moved to Chicago and later toCalifornia, where Clarence did his undergraduate work atStanford University. His family is now settled in Coles­ville, Md., nearly full circle for his parents, both of whomare originally from the Washington, D.C. area."I decided in the eighth grade to become a doctor," herecalls. "I took every science course I could from thenon, and liked them all." He belonged to the medical ex­plorer branch of the Boy Scouts, a group organized forstudents who are thinking about medical careers. In highschool he also worked as a hospital volunteer. "I amleaning now towards general practice medicine- primary27care. I have no aspirations to pursue a specialty, but younever know," he adds.The Navy program will give him a chance to explorehis interests outside of the medical school setting. Thissummer he will be doing research at the National In­stitutes of Health in Bethesda, Md. as part of his militaryobligation. The 45-day summer duty is usually dividedbetween research clerkships and clinical work.To unwind after a day in the classroom or before study­ing in the evening he plays "a little piano and a lot oftennis." The first year of medical school is very demand­ing inside and outside classes, but according to Clarence:"You have as much spare time as you make. My friendsand I started playing cards every Wednesday night to break up the routine of studying. We just use our timemore efficiently on the other days of the week.""Making" time for recreation is not the only thing thathas changed since he started medical school. After twodrought-dry winters in California, Clarence arrived inChicago for a record-breaking season of snowfall andbegan life in America's second city."I wanted to go to medical school in a city," he ex­plains. "I chose the University because of its reputationand because it offered an urban experience in medicalpractice. Part of medicine is integrating different experi­ences with the hope it will give you a better perspective. Iwanted to come here to do that."Maureen Brown" 'Mo' will probably be out running after school," re­ports her roommate. "Try calling her back after six."Maureen "Mo " Brown, 22, looks like a runner: long­limbed, slim and light. She entered track events for thefirst time in college and has stuck with it ever since."I am running more this year than ever before," shesays. "It releases pressure after work. It's a great way torelax." She runs with the University of Chicago TrackClub headed by Ted Haydon, a man whose philosophy oftraining runners excludes no one and includes Olympicmedalists.This summer Maureen is running nearly everyweekend and doing research work on campus during the28 week with Dr. Katherine Christoffel at Wyler Children'sHospital."I am working on two projects: a comparison of com­monly prescribed drugs for treating infection, and a sur­vey of the TV-watching behavior patterns of children,"explains Maureen.To help finance her education, she applied for and wasaccepted into the Public Health Service Program. "Thegovernment pays my tuition and a stipend while I'm inschool and then I work for the Public Health Serviceafterwards one year for each year of school support."The idea behind the program is to get doctors toshortage areas. The emphasis as been on placement inrural areas, but it is now shifting to the inner city."I am interested in working in a rural area," assertsMaureen. Perhaps this desire derives from wanting to besomeplace less urban. After growing up in Vienna, Va.,outside Washington, D.C., she came to the College ofThe University of Chicago to do her undergraduate work and remains here for her medical training.The Public Health Service Program offers a variety ofclinical jobs after graduation as well as an affiliated chan­nel for research work. Maureen wants to see patients. "Iam more clinically oriented than research oriented," shereflects.Bob BucciniBob Buccini co-sponsored a seminar with his collegeroommate at the University of Virginia and after it wasover they had traded majors."It was an independent, student-run seminar on medi­cal ethics," recalls Bob. "My roommate was a pre-medstudent and I was a philosophy major. We spent a yeargetting ready for it. I read books on medical ethics andmedical issues, attended seminars at the medical schooland talked with doctors."Slowly my interest in moral theology turned to medi­cal ethics and then to medicine in its own right. Month bymonth pure philosophy became less important and medi­cal questions in philosophy more appealing."Bob, 23, decided to begin a pre-med curriculum in histhird year, while continuing with his philosophy courses.His roommate, on the other hand, switched out of pre­med in favor of philosophy."I applied to The University of Chicago partly becausemy favorite philosophy professor had gone to schoolhere," says Bob. "The Divinity School and the graduatePhilosophy Department were strong here and after talk­ing with Dean Ceithaml [Dean of Students, Division ofthe Biological Sciences and The Pritzker School ofMedicine], he seemed open to my interest inphilosophy-in fact, he encouraged me. That sealed me,the resources were available and accessible as well."Bob was born in Naperville, Illinois, outside Chicago,the youngest of three children. His older sister has aM.B.A. degree. She works in business, like Bob's father.His older brother is deceased."I was never interested in business," explains Bob."In fact, though I want to be a practicing physician I amattracted to other things than medicine. I would like towrite and I enjoy the verbal side of life," he smiles.This summer Bob is working on a rural externship pro­gram in Kewanee, Illinois. The Illinois State Medical So­ciety sponsors the program, called Medical Educationand Community Orientation (MECO), which offers achance for medical students to work in small com­munities."I knew I would be exposed to urban medicine hereand wanted some experience in rural medicine," Bobcomments. "Most medical schools are in an urban settingand you see sophisticated patients, referrals from morethan one doctor sometimes. I wanted to see whatmedicine was like in a small community."He admits there is not much spare time during medicalschool but tries to manage it so that he gets some physicalexercises in during the week-bike riding or raquetball.During the Bicentennial year, he participated in a coast-to-coast bike ride involving 2,000 people and de­cided to do some research on the physical and physiolog­ical effects of riding. "I happened to mention the idea tosome other people, and it turned into a full-scale in­vestigation," he laughs.At the end of his first year of medical school, Bob isthinking about working towards internal medicine orsome kind of primary care field as a career goal. As forphilosophy, he hopes to integrate both professions in hispractice, making the contemplative life more than just anavocation.His rhetorical abilities have not been lost on his peers.He was elected as one of two representatives of the Classof 1981. Plato would probably have agreed that he is put­ting his philosophical training to good purpose.Robert ChenRobert Chen, 22, arrived in the U.S. from Taiwan withhis family at age ten. His parents had weathered Japaneseand Chinese ascendency on the island and added eachnew language to their native dialect, ending with Englishin America.The family now lives in Granada Hills, Calif., but Bobgrew up in the Chicago suburb of Elmhurst and attendedcollege at the University of Illinois at Champaign­Urbana.He spent the summer before medical school touringEurope with friends and as a student lives at the Inter­national House where he spends some of his free timereading foreign newspapers to keep up with world events. "I have travelled a lot," remarks Bob, "and had achance to meet different people and compare their cul­tures. As a result, I became interested in working withpeople as a career. Medicine has classically been a goodway to do this: as an advocate of human welfare whilederiving personal satisfaction."- Bob's medical interests encompass the preventive as­pects of health care as well as diurnal health questionslike, 'How can we teach people to take care of them­selves and maintain their health from day to day withoutcomplete dependence on physicians?'"With what I call a reductionist approach to medicineyou wind up with a lot of very expensive, sophisticatedtechnology," Bob says. "Instead there needs to be aharmonizing, a combining, of the reductionist approachand the public health view that good housing and goodfood are equally important priorities," he asserts. Bobsees this as a major concern in a world offinite resources,increasing population and expensive medical technology.He feels his interests in health care may lead to addi­tional studies after medical school, possibly involvingpublic policy work. As a member of the curriculum com­mittee this year, he has already gotten some administra­tive experience. The committee, made up of studentsselected by their class, reviews student evaluations ofcourses and presents an overview of the strong and weakpoints of the curriculum to a faculty group.This summer Bob is working at a community hospitalin a small Illinois town as part of an externship program."My original medical goals were to practice medicine in arural community," he explains. "Presently my interestsappear to be veering away from this, but even if! were toget involved in policy or administrative work for sometime, eventually I would like to get back to doing ruralmedicine. "Bob is the youngest of three children all of whom havepursued a biological sciences education. His sister re­ceived a degree in biology and is going on for a degree inart, and his brother graduated from the University of Il­linois's medical school last year.When asked for a reason why they all chose a similarfield of study he replies, "My parents contributedgreatly-an immigrant story of many sacrifices. Beyondthat, it just happened that the three of us were interestedin how things live and function."Virginia FreiThree of the seven Frei siblings were in medical schoolthis year. Virginia, 23, and an older brother and sister allgraduated from Carroll College in Montana, one after theother, and began medical studies at The University ofChicago, "the farthest east I've ever been," Virginiaconfesses.The Frei family owns a small crop farm in Ferdinand,Idaho, a town not large enough to have a high school."We went to school in Cottonwood, nearby," explainsVirginia. One brother is in school there now. Their edu-30 cation seems to have lacked nothing for its rural charac­ter. Aside from the three in medicine, one sister is study­ing to be a chemical engineer at the University of Idaho,and Virginia's twin brother has just been accepted at vet­erinary school. The oldest brother works on the farm."I enjoy our farm," says Virginia. "It's a nice feelingthat your home is in one place. Chances are my parentswon't move and going back there brings back a lot ofmemories of growing up."Virginia is spending this summer in Ferdinand workingas a clerk for the forest service 20 miles from home. Shehas worked there every summer since graduating fromhigh school doing a little of everything: fire control, busi­ness and finance, teletype, forest radios, and typing. "It'smy last summer at home," Virginia notes, "and I enjoythe work-it's a change."I found the first year of medical school enjoyable,"she continues. "It was better than I thought it would be. I like my classmates. There are none of the cliques of col­lege. After exams one-quarter to one-half of the class gottogether for a few beers. In our spare time five to ten of usplay racquetball."Virginia has not decided which area of medicine shewants to concentrate in, "I've thought a little about it,but I think I'll wait until rotations as ajunior and see whatI like before I decide," she declare s confidently.Joe GordonJoe Gordon, 23, thought seriously about pursuing automechanics before he decided to go to medical school.His father has a second garage at home in Los Gatos,California, fixed up with a grease pit where the two ofthem worked in the evenings and on weekends. Hisfather also put in time on carpentry, electronics, con­struction and general surgery.''I'm leaning in the direction of surgery, too," saysJoe. "I started this past quarter on an experiment with aresearch scientist under Dr. Moossa [A. Rahmin Moossa,Prof., Dept. of Surgery (Generalj] which won't involveme in surgery, but Dr. Moossa is giving me a chance towork with postdoctoral scientists who are doing surgicalresearch. "Both of Joe's parents are doctors. They are alsoalumni, and his grandfather, Dr. Louis Leiter, is an origi­nal faculty member of The University of Chicago MedicalSchool. Joe is the second offour children. His older sisterwill graduate from Duke University's medical school thisyear."I had an idea very early, about eight years old, that Iwould go into medicine. It is probably not surprising withboth parents practicing. I related much more easily tomedicine than studying biology," Joe explains. "I likethe lifestyle and philosophy of practicing medicine."As an undergraduate at Stanford University, he skiedwith the college team. While in Europe during his junioryear he skied in the Alps and spent 1 Yzmonths riding hisbike from London to Southern Germany. Studies have left less time for recreation since he started medicalschool. Though he and a friend used the time betweenclasses to run regularly, partly as a result of the wintersnow and the coursework, he has not ridden his bikemuch in Chicago. "I was not surprised at the workload,"says Joe. "I think you worry about it more than in col­lege, though-but it teaches you self-discipline," hesmiles.C reg Retzinger"Basically research is a lot of fun," admits Greg Ret­zinger, 23. As an M.D'/Ph.D. student he will spend sixyears at the University, much of it doing research."I'll be working straight through the summers for thenext six years," he explains, "but since that is what Iwant to do for the rest of my life it's fine."The 6'2" student is not only outstanding academically,having secured a full-tuition grant and living stipend tocover medical school expenses, he is also an excellentathlete.While on the basketball team at the College of TheUniversity of Chicago, his coach described him as "oneof the top defensive guards in the Chicago area" , a citywhich sees a lot of college court action. He was the cap­tain of his basketball team and received the University'sStagg scholarship, a four-year, full-tuition award basedon academic and athletic excellence in high school.In medical school this year he played on a city team inCabrini Green and also managed some intramural eventswith the medical school team. "Now I mostly play with afew friends," says Greg. He is busy in the lab.Greg's interest in research did not begin this year. Asan undergraduate in biochemistry he worked on slimemold aggregation in Dr. Theodore Steck's laboratory.This summer he is assisting in research on enhanced im­mune response as it relates to cancer in Dr. Robert Hunt­er's Cellular Immunology lab."I became interested in cancer research for personalreasons-a family member was affected. I looked up thekind of research the University was doing in cancer andtook a reading class with Dr. Hunter. He is doing some­thing I think is very useful. It helps me understandcancer," he adds.Greg is the fourth of five children. His family lives inRacine, Wisconsin. Briefly during his undergraduateyears he returned to Wisconsin to study. Since then hehas been in Chicago, and the research he is doing is pro­bably what makes him stay."It sounds hokey to say we might find a cure forcancer," Greg ventures, "but I feel what Dr. Hunter isdoing is going in the right direction-exploring the mech­anisms of tumor immunity."32Plus ca change,Plus c'est la merne chose.Name Graduation YearHome Address TelephoneCity, State, ZipBusiness Address TelephoneCity, State, ZipTitleNew address?New position?New medical practice?military assignment?civic or professional honor?book?Please tear out; fold, staple, or tape; and drop in the mailbox. Thanks!Medical Alumni Association1025 East 57th StreetChicago, Illinois 60637 '--------1I II II Place II II Stamp II II Here II I� J-------------------- ------------------------------------Fold this flap in firstDr. Dwight Clark RememberedIn the Department of Surgery history, which appeared inour 50th Anniversary issue, Dr. Dwight E. Clark's namewas inadvertently left off the list of departmental chair­men. Because of his long and productive association withour University, we decided that a simple correction inthis issue would not suffice and instead we offer this briefbiography of a man who was a great teacher, researcherand physician; one who was well-loved by those who hadthe pleasure of knowing him.Dwight Clark was born July 28, 1910 in Mount Eaton,Ohio. He was the son of a physician, and after he re­ceived his B.A. degree from Western Reserve Universityin 1932, he, too, pursued a medical education.As a student at the University of Rochester School ofMedicine, Dwight Clark spent a year of full-time researchin physiology with Professor Murlin and received anM.S. degree in 1935. Two years later he received hismedical degree from the same institution.In 1937 he came to The University of Chicago as anintern in the Department of Surgery. According to Dr.Lester Dragstedt (later chairman), Dr. Clark's "outstand­ing ability was immediately recognized and he was ap­pointed a Douglas Smith Fellow in 1938 and invited towork in my research laboratory. Here his sunny disposi­tion, his ability and his industry earned for him thefriendship and admiration of colleagues that expandedthroughout the remainder of his life."While he was a resident in surgery, Dr. Clark marriedEleanor Melander, a graduate of the College of the Uni­versity. It was a happy marriage, which gave them twodaughters, Judith (Mrs. Wallace Jones) and Elizabeth(Mrs. Steven Arch).Radioisotopes.When he completed his residency training in 1944, Dr.Clark took a leave of absence from the University andentered the U.S. Army. He was assigned to the Manhat­tan Project and served at Clinton National Laboratory inOak Ridge, Tennessee. There he was made chief ofsurgery and eventually commander of the Army Hospi­tal. His research work with plutonium at Clinton NationalLaboratory spurred an abiding and important interest inthe peaceful uses of radioisotopes.Dr. Clark returned to the University in 1947 as an as­sociate professor. He pioneered in the clinical use ofradioiodine for the treatment of thyroid diseases, includ­ing cancer, and was conversly, one of the first to definethe association between exposure to radiation in child­hood and subsequent thyroid cancer. He also developedthe laboratory methods for evaluating thyroid functionswhich made studying the effects of radioiodine therapypossible.In 1951, Dr. Clark was promoted to professor in theDepartment of Surgery, and made senior attending sur­geon of Billings Hospital and Secretary of the Depar­ment. Seven years later he was named chairman.He served briefly, from July 1958 until July 1959, whenhe died of hepatitis, only four days before his forty-ninthbirthday. A Chicago medical columnist characterized Dr. Dwight Clarkhim, somewhat dramatically, but no less justly, as a mar­tyr to medicine.Dr. Clark's membership in professional societies wasextensive over the years. Most notably he was vice pre­sident of the Society of Nuclear Medicine and a memberof the Board of Governors of the American College ofSurgeons.Great PhysicianThough his academic credentials were outstanding, Dr.Clark was, above all else, a great physician."Dwight was one of those unusual individuals whohelped to make The Clinics [The University of ChicagoClinics] great by drawing to it patients who would havecome to him no matter where he was. It was more than afollowing built upon a great reputation. It was almost acult ... Externs who heard Dwight explain [a] patient'scase will never forget the patient's look of security andpride in the knowledge that his life-its medical historyand its human problems and interests-had been made apermanent part of the life of his physician. It is littlewonder that we who knew him well feel forever attachedto him." (Medical Alumni Bulletin, Autumn 1959)During his all-too-brief tenure as chairman, Dr. Clarkembarked on an ambitious, long-range plan for the De­partment of Surgery. He added excellent surgeons to thestaff, and was actively recruiting others. He was in theprocess of reviewing and reevaluating the teaching pro­gram, and had plans for enlarging the research programfor the surgical staff. Ironically, the announcement ofplans to construct an Armour Clinical Research Buildingwas made just a few days before Dr. Clark died.This spring, nineteen years later, the Department ofSurgery moved into the new Surgery-Brain ResearchPavilion, a facility where physician-researchers will pur­sue the work of advancing medicine and treating patients.It is only fitting that Dr. Clark should be remembered asthis new surgery complex assumes its place in the currenthistory of the University's Medical Center.35News BriefsRicketts AwardThe 1978 recipient of the Howard TaylorRicketts Award, Dr. Purnell W. Chop­pin, professor of the Rockefeller U niver­sity Hospital, presented the annual Ric­ketts Lecture May 8. His topic was "TheStructure and Function ofParamyxovirus and Myxovirus Mem­branes. "Golomb Selected by JayceesDr. Harvey M. Golomb, assistant pro­fessor in the Department of Medicine,was honored by the Chicago Jaycees asone of Ten Outstanding Young Citizensfor 1978. Each year the Chicago civicgroup chooses ten young adults whoshow interest in their social servicegoals. Dr. Golomb was chosen fromamong 54 nominees.Three Faculty listed Among BestSeveral University physicians werelisted in TOII'n and Country, February1978, as being among the best medicalspecialists in the United States.Listed were:Dr. John Mullan, the John HarperSeeley professor in the Department ofSurgery, head of the section ofNeurosurgery and director of the BrainResearch Institute: Dr. Joseph B. Kirs­ner , the Louis Block Distinguished Ser­vice Professor in the Department ofMedicine: and Dr. Irwin Rosenberg, pro­fessor in the Department of Medicineand head of the section of Gastroenterol­ogy.Among specialized treatment centers,The University of Chicago Cancer Re­search Center was listed along with otherfederally-funded national cancer re­searc h cen te rs.Alumni Event RecognizedThe University Medical Center has beenawarded the Exceptional AchievementAward of the Council for Advancementand Support of Education (CASE) for its50th Anniversary Celebration of medicaleducation and patient care at the U niver­sity.The award was presented in the cate­gory of alumni events. There were 3000entries submitted this year by the 1900member institutions of CASE (Collegeand Universities).Cancer Prize EstablishedThe first Simon M. Shubitz Cancer Prizeand Lectureship offered by the Divisionof the Biological Sciences and the Pritz­ker School of Medicine was awarded toBruce N. Ames, professor and chairman36 of the Department of Biochemistry at theUniversity of California at Berkeley,Dr. Shubitz, a 1935 alumnus of TheUniversity of Chicago and Rush MedicalCollege, endowed the Medical Center'snew cancer award and visiting lecture­ship, which was created to bring to thecampus scientists who have made sig­nificant contributions to the cancer prob­lem.Professional Achievement AwardLeonidas H. Berry ('30 Rush), was hon­ored by The University of ChicagoAlumni Association at the 38th AnnualAwards Ceremony May 20.Dr. Berry received the ProfessionalAchievement Award which recognizesthose alumni whose attainments in theirvocational fields have brought distinctionto themselves, credit to the Universityand real benefit to their fellow citizens.Former President of the National Med­ical Association, Dr. Berry has for manyyears directed his medical career towardthe solution of problems affecting thewelfare of the community at large. He isa specialist in the fields of gastroenterol­ogy and endoscopy, and his career­related activities have included the re­cruitment of young black students to themedical profession and significant volun­tary work in the treatment of alcoholismand drug addiction. therapy of gastric cancer, differentiationof benign and malignant lesions in thestomach, the use of radiation in thetreatment of peptic ulcers, and the effectof such radiation on the gastric glands.Dr. Palmer served as president of theCollege 1956-57.Dorfman Gives Ryerson lectureDr. Albert Dorfman (,44), the Richard T.Crane Distinguished Service Professor inthe Department of Pediatrics, deliveredthe fifth Nora and Edward Ryerson Lec­ture at the University March 29.His topic was" Answers WithoutQuestions and Questions without An­swers," in which he described his ownresearch on birth defects, mental re­tardation and the chemistry of connec­tive tissue, as well as the ethical dilemmaposed by learning of fetus defects.The Ryerson Lecture was establishedby the Trustees of the University in 1973.The chosen speaker is mandated to lec­ture to an audience from the entire Uni­versity on his or her major intellectualwork.Humanitarian AwardDr. Louis Gluck ('52), professor ofPediatrics and Reproductive Medicine atthe University of California at San Diegowas presented the third Joseph Boli varDeLee Humanitarian Award at the an­nual director's dinner sponsored by theDr. and Mrs. Walter Palmer.Walter Palmer HonoredWalter Lincoln Palmer ('21) was pre­sented the John Phillips Memorial Awardof the American College of Physicians inApril at its annual meeting in Boston.The award recognizes a physician "fordistinguished contributions in internalmedicine. "Dr. Palmer's contributions are chieflyin the area of gastroenterology and in­clude the demonstration of the mecha­nism of pain in gastric and duodenal ul­cers, investigation of their treatment, Board of Directors of the ChicagoLying-in Hospital April 29.Dr. Gluck's major contribution tomedical science to date is related to hisintensive studies of lung maturity in thedeveloping fetus and he is credited withthe development of a critical test for pre­dicting lung maturity.The Joseph Bolivar DeLee Award ispresented each year to an individual whohas made an outstanding contribution tothe health care of women.Basic Science Teaching AwardDr. Frank Fitch ('53), the Albert D.Lasker Professor in the Department ofPathology, has been chosen by thefreshman and sophomore medical stu­dents to receive the Basic SciencesTeaching Award. This award recognizesand honors a faculty member teaching inthe basic science curriculum, who hasshown dedication and excellence in histeaching. The award is voted upon byeach successive sophomore class at theend of their pre-clinical training.The Cold Medal of the Barany Society.Barany Society Honors FernandezDr. Cesar Fernandez, professor emeritusin the Department of Surgery (Otolaryn­gology), received the Gold Medal of theBarany Society in Uppsala, Sweden June5.The medal is awarded every five yearsto an author "regardless of nationality orrace, who, during the last five-yearperiod, has published the most valuablework concerning the vestibular ap­paratus, in the widest sense of the term."Two long-Time Faculty MembersMark Anniversaries of ServiceDr. John R. Lindsay, the Thomas D.Jones Professor in the Department ofSurgery (Otolaryngology) marked his50th year with the University facultyJuly I. Dr. Lindsay, who received his M.D.from McGill University School ofMedicine, joined the Chicago faculty in1928. He was chairman of the Section ofOtolaryngology from 1929 to 1966 andtrained many of the ear, nose and throatsurgeons who now head otolaryngologydepartments in this country and someabroad.He is the author or co-author ofnumerous articles on the physiology ofhearing and the histology and his­topathology of the ear. He also foundedThe University of Chicago TemporalBone Bank in 1931 for the study of deaf­ness and vertigo. As a result, the Uni­versity's otolaryngology section has oneof the largest collections of pathogenichuman temporal bone in the world.Dr. Lindsay has held numerous officesin professional ENT societies and wasawarded a prestigious honorary degreefrom the University of Uppsala, Sweden.Dr. Lindsay will be honored at a scien­tific symposium November 10 to be heldat the University's Center for ContinuingEducation. Distinguished alumni of theSection of Otolaryngology will be invitedto present papers at the symposium. Atestimonial dinner will follow.Dr. Frank W. Newell, Chairman of theDepartment of Ophthalmology, cele­brated h is 25th year of service to theUniversity May I.Dr. Newell has been chairman of thedepartment since 1970 and headed theSection of Ophthalmology from 1953until it became a department in 1970. Hereceived his M.D. from Loyola Univer­sity and served as an instructor and as­sociate professor of ophthalmology atNorthwestern University before comingto Chicago.The Ophthalmology faculty honoredDr. Newell at an evening gathering at theQuadrangle Club in June when they un­veiled a portrait of him they had hadcommissioned in celebration of his an­niversary.Michael Reese-PritzkerAppointmentsThe following members of MichaelReese Hospital and Medical Center werenamed to the staff of the Pritzker Schoolof Medicine. Names received after pub­lication date are not included.MedicineAppointments effective July I, 1978 fortwo years or as listed:Dr. Muhammad Ali-Clin. Instr.: Dr.Michael Berelowitz-Instr.: Dr. Jacob D.Bitran-Clin. Ass t. Prof'.: Dr. FreddieDaniels-Clin. Instr.: Dr. Gerald Farby ('75)- Instr.: Dr. John Farmer-Clin. Instr.: Dr. Wal­ter Fried-Prof.; Dr. Satish Kathpalia-Instr.:Dr. Mark Kozloff-CJin. Instr.: Dr. GopalLalmalani-Clin. Instr.; Dr. David Lieb-Clin.Instr.: Dr. Evan McLeod-Asst. Prof.; Dr.Rima McLeod-Asst. Prof.: Martha Nakao,Ph.D.-Res. Assoc. (Asst. Prof.) (1 year); Dr.Reuben Nichols-Clin. Instr.; Dr. DenisRubenstein-Instr.: Dr. Martin Sachman-Clin.!nstr.: Dr. William Schwartzman-Clin. Instr.:Dr. Mark Shields-Clin. Instr.: Dr. LauraSimon-Clin. Instr.: Dr. Drew Tomczak('73)-Clin. Instr.: Dr. Nila Vora-Clin. Instr.:and Dr. Winston Thein-Wai-Clin. Instr.Promotions:Dr. Oscar Moore-Clin. Asst. Prof'.: Dr.Edward Newman-Clin. Prof.: Dr. James C.Sheinin-Clin. Assoc. Prof.: and Dr. AllanSutow-Clin. Asst. Prof.Reappointments effective July 1, 1978for two years or as listed:Dr. Arthur A. Billings-Clin. Assoc. Prof.:Dr. Thomas Carlson-Clin. Instr.; Dr. AntonioChan-Clin. Instr.: Dr. Juan Chediak -Asst.Prof.: Dr. Sheldon Cogan-Clin. Assoc. Prof.:Dr. Sidney Cohen-Prof. (I year): Dr. IvanD'Cruz-Asst. Prof. (I year); Dr. Samuel DeNosaquo-Clin. Instr.: Dr. Richard Desser­Clio. Asst. Prof.: Dr. Michael H. Ellman­Asst. Prof. (3 years): Dr. Juan Engel-Asst.Prof. (3 years): Dr. Murray Favus-Asst. Prof.(3 years): Dr. Fred Fishman-Clin. Instr.; Dr.David F. Fretzin-Clin. Assoc. Prof.: Dr.Lawrence A. Frohman-Prof. (without lengthof time); Dr. Clarence Gantt-Assoc. Prof. (5years): Dr. Gerald Glick-Prof. (without lengthof time): Dr. Alberto Goldbarg-Assoc. Prof.(5 years): Dr. John N. Goldman-Asst. Prof. (3years): Dr. Raj G. Gupta-Ass!. Prof. (3years); Dr. Imtiaz Hamid-Clin. lnstr.: Le RoyJ. Hirsch, Ph.Dv-Asst. Prof. (3 years); Dr.Robert Holstein-C1in. Instr .: Dr. AlanKanter-Clin. Assoc. Prof'.: Dr. MabelKoshy-Asst. Prof. (3 years): Dr. RichardLangendorf-Clin. Prof. (1 year); Dr. Noah B.Levin-Clin. Prof.: Dr. Richard Levinsky­Asst. Prof. (3 years); Dr. Dennis Levinson­Asst. Prof. (3 years): Dr. Victoria Lim-Asst.Prof. (3 years): Dr. Irving Mack-C1in. Prof.:Dr. Jerome Mehlman-Clin. Prof. (1 year): Dr.Cyril E. Mendelson-Clin. Asst. Prof.; Dr. Er­nest Mond-Clin. Assoc. Prof.: Dr. RobertMutterpearl-Clin. lnstr.; Dr. August V.Paredes-Clin. Asst. Prof.: Dr. Alfred Pick­Prof. Emeritus: Dr. Ruth Pick-Prof. (I year);Kenneth C. Robbins, Ph. D.-Prof. (withoutlength of time): Dr. Stewart J. Rosenfeld­Clin. Asst. Prof.: Dr. Leslie Sandlow-Assoc.Prof. (5 years): Dr. Charles M. Shapiro ('54)­Clin. Prof.: Dr. Earl N. Silber-Clin. Prof.: Dr.Dennis Sloan-C1in. Instr.: Dr. Gerald Sobel­C1in. Asst. Prof.: Dr. Mitchell Spellberg-Clin.Prof. (1 year): Dr. J. Peter Szidon-Assoc.Prof. (5 years): Dr. Arnold Tatar-Clin. Assoc.Prof.: Dr. Margaret Telfer-Ass!. Prof. (3years); Dr. Edward Walton-Clin. Instr.: Dr.Robert Weinstein-Asst. Prof. (3 years); Dr.Julian Zinder-Clin. Asst. Prof'.: Dr. L. DavidZinn-Clin. Asst. Prof. (l year); and Dr. IrvingZitman-Clin. Prof.NeurologyAppointment effective July 1, 1978 fortwo years:Dr. Irving Sherman-C1in. Prof.37PathologyAppointments effective July 1, 1978 forthree years;Margaret Goldman, Ph.D.-Ass!. Prof.: andDr. Armando Orlina-Asst. Prof.PediatricsAppointments effective July 1, 1978 forthree years or as listed:Dr. Samuel Gotoff-Prof. (without length oftime): Dr. George Lambert-Asst. Prof.: Dr.Eddie S. Moore-Assoc. Prof. (5 years): Dr.Elda H. Sim pson-Asst. Prof'.; Dr. Bonn ieTyplin-Instr. (1 year): and Dr. Lawrence C.Vogel-Asst. Prof.Reappointments effective July I, 1978for three years or as listed:Dr. Pipit Chiemmongkoltip-Asst. Prof.: Dr.Arthur H. Rosenblum ('35)-Clin. Prof. (Iyear): Dr. Irving H. Rozenfeld ('47)-Clin. Prof. (2 years): and Dr. Charles Swisher­Asst. Prof.PsychiatryAppointments effective July 1, 1978 forone year:Dr. Harry Fine-Clin. lnstr.: Dr. MaxForman-Clin. Assoc. Prof.: Mark J. Gehrie,Ph.D.-Res. Assoc. (Asst. Prof.): Dr. RobertGreendale-Clin. Lnstr .: Dr. CharlesKitchen-Clin. Instr.: Vita Krall, Ph.D.-Res.Assoc. (Asst. Prof.): Dr. Mark Levey-Clin.Asst. Prof.: Mary Rootes, Ph.D.-Res. Assoc.(Asst. Prof.): Dr. David Roth-Clin. Asst.Prof.: and Dr. Harry Soloway-Chn. Asst.Prof.Promotions effective July 1, 1978 for oneyear:Dr. Michael Basch-Clin. Prof.: Dr. ArnoldGoldberg-Clin. Prof'.: and Dr. SidneyWeissman-A sst. Prof.Dr. Allan T. Kenyon Dr. Dwight /. IngleIn MemoriamM. Edward Davis, 1899-1978Dr. M. Edward Davis, the JosephBolivar DeLee Professor Emeritus inObstetrics and Gyrreco logy , died inGlenview, Illinois, February 6.Dr. Davis served as chairman of theDepartment of Obstetrics and Gynecol­ogy and as chief of staff of the ChicagoLying-in Hospital from 1954 until his re­tirement in 1966. He received his B.S.degree from The University of Chicago in1920and the M.D. from The University'sRush Medical College in 1922.At a memorial service held in BondChapel March 31, Dr. Arthur Herbst,chairman of the Department of Obstet­rics and Gynecology characterized Dr.Davis as "one of the early pioneers whosupported and helped to advance the sci­entific basis of clinical medicine."'His scientific interests and ac­complishments centered in the areas ofmaternal-fetal medicine and endocrinol­ogy and his written contributions to themedical literature numbered over 150 ar-38 .tDr. M. Edward Davisticles which covered all aspects ofobstetrics and gynecology."Three of Dr. Davis's associates gavetributes at the memorial service: Drs. H.Close Hesseltine, Charles P. McCartneyand Antonio Scommegna. Each spoke ofDr. Davis's clinical acumen and contri­butions to the department.He received many honors both in theUnited States and foreign nations. Ac­cording to Dr. McCartney, among Dr.Davis's most cherished honors were theJoseph B. DeLee chair and the Gold Keyof the Medical Alumni Association.Dr. Davis is survived by his wife,Jeanette; his daughter, Barabara Boden;his son, M. Edward, Jr., and one grand­child.Memorial gifts may be made toChicago Lying-in Hospital, 5841 Mary­land Avenue, Chicago, Illinois 60637.Dwight J. Ingle, 1907-1978Dr. Dwight J. Ingle, Professor Emeritusin the Department of Pharmacologicaland Physiological Sciences, died InTraverse City, Michigan, July 28.Dr. Ingle joined the University ofChicago faculty in 1953 as Professor of SurgeryAppointments effective July I, 1978 fortwo years or as listed:Dr. Richard Bendix-Clin. Prof'.: Dr.Charles D. Campbell-Asst. Prof. (3 years):Dr. Jerome J. Finder-Clin. Prof.: Dr. Saul S.Haskel-Clin. Assoc. Prof.: Dr. Morris D.Kerstein-Assoc. Prof. (5 years): Dr. MitchellKrieger-Clin. Asst. Prof.: Dr. Gerald J.Menaker-Clin. Prof.: Dr. Henry L. Moss,Jr.-Clin. Instr .: Dr. David D. Presman-Clin.Prof.: Dr. Charles L. Rice-Asst. Prof.: Dr.Lawrence Rubenstein-Clin. Assoc. Prof.: Dr.Richard A. Shapiro-Clin. Assoc. Prof.: Dr. 1.Thomas Sheridan-Clin, Prof.: Dr. I. JoshuaSpiegel-Clin. Prof.: Dr. S. LloydTeitelman-Clin. Prof.: Dr. Milton Tinsley­Prof.: Dr. Leonard Weinstein-Clin. Prof.: andDr. Carlton A. West-Clin. Instr.Physiology in the Ben May Laboratoryfor Cancer Research. He was chairman ofthe former Department of Physiology'(now the Department of Pharmacologicaland Physiological Sciences), from 1959to1968, and retired as Professor Emeritus in1973.A nationally known physiologist andformer president of several scientific or­ganizations, Dr. Ingle, in the 1950s,established the role steroid hormonesplayed in permitting animals and humansto s urvi ve stress.He was a member of the NationalAcademy of Sciences and the AmericanAcademy of Arts and Sciences. He wasfounder and editor of Perspectives inBiology and Medicine and the author ofseveral books.Dr. Ingle was born in Idaho andgraduated from the University ofIdaho in1929. He received the M.S. (1931) andPh.D. (1941) degrees from the Universityof Minnesota. Following his retirementfrom The University of Chicago faculty,he taught as a visiting professor at theUniversity of Idaho.He is survived by his widow, Geneva,of Rapids City, Michigan, a son, David,and daughters, Ann and Jane.A memorial services will be held thisfall. Memorial gifts may be made to Per­spect ives in Biology and Medicine, 1025E. 57th Street, Chicago, Illinois 60637.They will be used for prizes awarded byPerspectives each year in its young au­thors contest.Allan T. Kenyon, 1900-1978Dr. Allan T. Kenyon, ProfessorEmeritus of Medicine and former chief ofEndocrinology at The University ofChicago, died May 26 at the University'sMedical Center.Dr. Kenyon pioneered the study of vir­ilizing and growth-promoting effects ofmale hormones. He originated the treat-ment program for administering testos­terone to victims of a loss of testicularfunction.A native of Rochelle, Illinois, he was a1920 graduate of the University of Il­linois and received his M.D. from TheUniversity of Chicago Rush MedicalSchool in 1925.He joined the medical faculty of theUniversity in 1929 shortly after the open­ing of Billings Hospital and organized itsendocrinology section, which he headeduntil his retirement.A memorial service was held for Dr.Kenyon at Bond Chapel May 26. Dr.Richard Landau, professor in the De­partment of Medicine, and a former stu­dent, gave the tribute. Quoting from aeulogy that Dr. Kenyon had given in1963 for another scientist, Dr. Landausaid: .. And so the long pri vi lege of know­ing you has not closed. We return to youthis afternoon, and will many timesagain. You earned many honors, and ofthese we are proud. Your faculty familythinks now as well of your gifts to theday by day. "Dr. Kenyon is survived by his wife,Lois: sons, Richard and Thomas:daughters, Barbara Whitemore andJudith Kirscht: nine grandchildren and abrother, David.For memora! gifts see box.Memorial FundA memorial fund has beenestablished which will be used toprovide loans to medical students.I personally know of no better wayto honor the memory of Allan T.Kenyon, an eminent endo­crinologist, teacher, and gentle­man. Dr. Kenyon associated withstudents throughout most of hislifetime, and they recognized himas an excellent teacher and as awarm and sympathetic friend andcounselor.I invite you to join me in thistribute to this truly great individualwho did so much for our Univer­sity and for our medical school.Your gift should be made pay­able to The University of Chicagoand sent to The Allan T. KenyonMemorial Fund, Culver Hall-400,1025 East 57th Street, Chicago, Il­linois 60637.Dean of Students Alumni Deaths, I!. Curtis E. Mason, Portland, Oregon,'September 23, 1976, age 96.'12. Claude W. Carr, Riverside,California, September 6, 1977, age 93., 12. Arthur Goetsch. Fort Lee, NewJersey, October 18, 1977, age 91.'14. Gilbert E. Brereton, Dallas,Texas, November 3,1973, age unknown.'17. Benjamin J. Clawson, Stockton,California, December 23, 1977, age 96.'17. Florence P. Gebhart, Clearwater,Florida, February 13, 1978, age un­known.'17. William J. Henry, Chester, SouthCarolina, February 8, 1977, age 87.'18. Clark W. Finn erud, Minocqua,Wisconsin, October 10, 1977, age 82.'19. Virgil S. Counseller, Scottsdale,Arizona, December 23, 1977, age 85.'19. Claude S. Mamma, Polo, Illinois,December 16, 1977, age 83.'19. Edward F. Studer, Tucson,Arizona, March I, 1977, age 84.'21. Dean C, Burns, Petoskey, Michi­gan, February 9, 1978, age 82.'21. Arthur R. Colwell, 51' .. Evanston,Illinois, June 4, 1978, age 80.'21. Andrew C. Ivy , Oak Park, Illinois,February 7, 1978, age 85.'21. Bernard P. Mil lien , Seattle, Wash­ington, February 28, 1978, age 85.'21. Abraham H. Rudolph, MiamiBeach, Florida, March 3, 1978, age 82.'21. Charles G. Weller, Aurora, Il­linois, October 18, 1976, age 81.'22. M. Edward Davis, Sr., Winnetka,Illinois, February 6, 1978, age 79.'22. Lloyd H. Fox, Bakersfield,California, January 1978, age 82.'23. Beatrice Hawkins, College Sta­tion, Texas, March 8, 1978, age 83.'24. WinJi'ed W. Hawkins. College Sta­tion, Texas, November 25, 1976, age 84.'24. Kathleen B. Muir, Chicago, Il­linois, March 7,1978, age 79.'25. Manuel E. Lichtenstein, Chicago,Illinois, December 3, 1977, age 77.'26. Allan T. Kenyon, Chicago, Il­linois, May 26, 1978, age 77.'26. Linton G. Weed, Exton, Penn­sylvania, December 15, 1976, age 82.'27. Joseph Major Greene, Chicago,Illinois, March 1978, age 77.'28. Ian H. Bond, Ormond Beach,Florida, October 28, 1977, age 80.'29. Harold B. Elliot, Springfield,Ohio, April 9, 1978, age 77.'29. Edgar Lutz, Los Angeles,California, December 16, 1977, age 76.'29. James I. Farrell, Evanston, Il­linois, October 30, 1977, age 77.'29. Edwin H. Ober, Painted Post,New York, March 25, 1978, age 76.'29. Joseph A. Tut a, Palos VerdesEstates, California, April9, 1978, age 78.'30. Rolland C. Bates, Binghamton, New York, April 19, 1978, age 76.'30. Martin F. Gaynor, Indian Or­chard, Massachusetts, January 11,1978,age 76.'30. J. Phil Redgwick , Omaha, Ne­braska, September 6, 1977, age 74.'33. Hamilton H. Greenwood, CoeurD'Alene, Idaho, February 8, 1977, age73.'33. Stanley L. Hardy, Las Vegas,Nevada, March 12, 1976, age 70.'34. William H. Sheldon, Jr., Cam­bridge, Massachusetts, September 16,1977, age 78.'35. LOllis A. Avallone, Lowville, NewYork, February 1, 1978, age 69.'35. John M. Buchanan, Laguna Hills,California, March 19, 1978, age 70.'35. R. H. K. Foster, Franklin, In­diana, July 18, 1976, age 74.'35. Herbert Janson, Homewood, Il­linois, July 23, 1977, age 77.'35. Karl P. Klassen, Columbus,Ohio, May 6, 1978, age 70.'35. Richard N. Washburn, Elmhurst,Illinois, July 28, 1977, age 70.'37. William Weinstein, Seattle, Wash­ington, September 15, 1977, age 67.'38. Gerard J. Alo n ;o , NorthCaldwell, New Jersey, June 22, 1977, age64.'39. Oll'en G. McDonald, LakeForest, Illinois, November 19, 1977, age65.'40. William B. Smith, Kentfield,California, July 16, 1977, age 63.'41. Michael M. l van , Grapeview,Washington, March 4, 1978, age 66.'44. Charles W. Schlageter, Evanston,Illinois, July 18, 1977, age 57.'45. Paul E. Strueh , Evansville, In­diana, August 29, 1977, age 57.'48. Clement E. Brooke, Columbia,Missouri, August 15, 1977, age 60.'48 Edward Laverman Racine, Wis­consin, March 10, 1978, age 56.'49. Harold C. Deering, La Mirada,California, August 1977, age 64.'55. William P. Cohen, Berkeley,California, March 18, 1978, age 48.Former StaffDwight J. Ingle, (Physiology, Professor,'53-'73; Chairman '59-'68), TraverseCity, Michigan, July 28, 1978, age 70.Waman M. Kale (General Surgery, Res­ident, '65), La Grange, Illinois, March 5,1977, age 49.Robert Kohrman (Psychiatry, Lec­turer, '67-'77), Chicago, Illinois, Octo­ber 6, 1977, age 58.James H. Salt (Psychiatry, ClinicalAssociate Professor, '74-'78) Chicago,Illinois, February 24, 1978, age 51.Harwell Wilson (General Surgery,Intern, Resident, '32-'39; Instructor,'38-'39), Memphis, Tennessee, October12, 1977, age 68.39Departmental NewsAnatomylorna P. Straus (,62 Ph.D.), AssociateProfessor in Anatomy, the College, andDean of Students and Associate Dean ofthe College, was elected to serve on theCommittee of the Council of the U niver­sity Senate for a one-year term beginningJuly I.Ben May laboratoryElwood V. Jensen ('44 Ph.D.) deliveredthe 59th Mellon Lecture on the topic"Estrogen Receptor Interaction inTarget Cells" at the University ofPittsburgh on May 11. Dr. Jensen is theCharles B. Huggins Professor and Direc­tor of the Ben May Laboratory forCancer Research and Professor in the'Departments of Biophysics and Theoret­ical Biology and Pharmacological andPhysiological Sciences.Dr. Jensen was honored by CancerResearch in their cover story for May.The cover included his photograph and adiagram which is a schematic representa­tion of the interaction pathway of estra­diol in a uterine cell.BiologyThe Biology Department garden is beingrelocated to 5622 Drexel Avenue nearthe greenhouse in order to make the pre­sent site available for construction of aUniversity -the ater. This garden is usedby the Biology Department for a varietyof plant experiments, most notably thecurrent studies with corn being con­ducted by Dr. George W. Beadle, Nobellaureate and the William E. Wrather Dis­tinguished Service Professor Emeritus inBiology and the College. It is also usedas a site for preparation of materials foruse in the greenhouses.Jeanne Altmann, Research Associatein the Department of Biology, waselected to a five-year term as AmericanEditorofAnimal Behavior, The quarterlyjournal is ajoint publication of the AnimalBeha vior Society and its British counter­part, the Association for the Study ofAnimal Behavior.Terrence E. Martin, Associate Pro­fessor in the Department of Biology, lec­tured in Scotland, England, France andGermany from May 19 to June 9. Hissubject was "Questions of Structure andFunction, etc."Aron A. Moscona, the Louis BlockProfessor in the Departments of Biologyand Pathology, was appointed to the fol­lowing committees: Basic Research Ad-40 visory Committee of the National Foun­dation of the March of Dimes, the Advi­sory Panel for the American Institute ofBiological Sciences-NASA Space Biol­ogy Council, and the Executive EditorialBoard of Developmental Neuroscience.Professor Moscona also served as co­organizer and co-chairman to an Inter­national Conference on DevelopmentalNeurobiology in conjunction with theEuropean Molecular Biology Organiza­tion (EMBO) and the International Soci­ety of Developmental Biologists (lSDB),held in Naples, Italy, May 22-27.Arnold W. Ravin, the Addie ClarkHarding Professor, in the Departmentsof Biology and Microbiology, spoke on"Genetic Modification: Lessons of His­tory" at the Lawrence Academy, Gro­ton, Massachusetts on May 4.Professor Ravin in August attendedthe 4th European Meeting on Transfor­mation in York, England and spoke onthe research being carried out in his lab­oratory.Biophysics and Theoretical BiologyMorrell H. Cohen, the Louis Block Pro­fessor of Physics Department ofBiophysics and Theoretical Biology, andthe College, was recently elected amember of the National Academy of Sci­ences.Prof. Morrell H. Cohen Emergency MedicinePromotions:Dr. Jack B. Franaszek-Assistant Pro­fessor.Dr. Robert J. Rothstein-AssistantProfessor.Dr. Frank J. Baker II, Assistant Pro­fessor and Acting Director of EmergencyMedicine, was nominated by the Na­tional Committee of the American Col­lege of Emergency Physicians (ACEP) torun for the National Board of Directors.Dr. Baker is past president of the Illinoischapter of ACEP.Dr. Jack B. Franaszek, Assistant Pro­fessor, was elected to the Board of Di­rectors for the Illinois Chapter of ACEPand was appointed the Chairman for thenext Combined Scientific Assembly,1978-1979.Dr. Robert J. Rothstein, Assistant Pro­fessor, was elected to the Board of Di­rectors for the Illinois Chapter of ACEPand appointed to a two-year term as aCouncillor to the National Council ofACEP.MedicinePromotion:Dr. Charles Winans-Professor.Dr. Leslie J. De Groot, Professor in theDepartments of Medicine and Radiology,was appointed Head of the Endocrinol­ogy Section. He succeeds Dr. RichardLandau who served ten years as sectionhead.Dr. Joseph B. Kirsner, the Louis BlockDistinguished Service Professor ofMedicine, received a citation in recogni­tion of his professionalism and ac­complishments in the field of gastroen­terology from the Tufts School ofMedicine where he received his M.D.degree in 1933. He was presented thefirst "Dean's Society of DistinguishedGraduates Award" during alumniweekend in Boston.Dr. Kirsner has the first OutstandingLeadership award of the National Foun­dation for Ileitis and Colitis (NFIC) forconquering inflammatory bowel disease.The Foundation also announced the in­itiation of an NFIC Honorary Joseph B.Kirsner Lecture Series on inflammatorybowel disease, which is to be given as aservice to the medical community. Dr.Kirsner has served for the past fouryears as Chairman of the Scientific Advi­sory Committee of the Foundation.He presented the AOA Lecture enti­tled "Inflammatory Bowel Diseases: TheRosetta Stone of Modern Medicine" atRush Medical School, Chicago, May 12.Dr. Irwin H. Rosenberg, Professor inthe Department of Medicine and head ofthe Section of Gastroenterology, waselected to serve on the Committee of theCouncil of the University Senate for aone-year term beginning July l.Dr. Janet Rowley, (,48) Professor inthe Department of Medicine and theFranklin McLean Memorial ResearchInstitute, was elected to a three-yearterm as a trustee for the AdlerPlanetarium.On May 28 on WGN Radio and 120other radio stations on the program" Re­viewing Stand" she discussed scienceresearch and funding.MicrobiologyAppointment:Michael Loken, Ph.D.-Assistant Pro­fessor.Promotion:Patricia G. Spear ('69 Ph.D.)­Associate Professor.Bernard S. Strauss, Professor andChairman of the Department of Mi­crobiology, attended the InternationalMeeting on DNA Repair and Late Ef­fects in Tel Aviv, Israel, May 1-5.OphthalmologyDr. Frank W. Newell, the James N. andAnna L. Raymond Professor and Chair­man of the Department, was elected anhonorary member of the Ophthalmologi­cal Society of Colombia, South America.PathologyAppointment:Dr. Joseph D. Locker (,75)-AssistantProfessor.Dr. James E. Bowman, Professor in theDepartment of Pathology and Medicine,Medical Director of the Blood Bank, Di­rector of Laboratories, and Director ofthe Comprehensive Sickle Cell Center,along with Eugene Goldwasser (' 50Ph.D.), Professor of Biochemistry, pre­sented a 30-minute, 16 mm. color-soundfilm on "Sickle Cell Fundamentals" tothe Greater Chicago area Chapter of theAmerican Medical Writers Association.The Center's film was governmentfunded. Last year the ComprehensiveSickle Cell Center received the GoldenEagle Award of the Council on Inter­national Nontheatrical Events (CINE)for their five-minute educational film,"Sickle Cell Anemia".PediatricsAppointments:Dr. Herbert J. Krantman-AssistantProfessor.Dr. Jay Berkelhamer, Associate Pro­fessor in the Department of Pediatrics and Director of the Wyler Hospital Am­bulatory Services, was one of six physi­cians chosen to receive the Robert WoodJohnson Health Policy Fellowship for1978-79. The fellowships, established bythe Institute of Medicine with a grantfrom The Robert Wood Johnson Founda­tion, provide a better understanding inhealth policy and federal health pro­grams. This fall, Dr. Berkelhamer willtravel to Washington, D.C. to begin theyear-long program which is administeredby the Institute of Medicine and theAmerican Political Sciences Association.His assignment will be working in the of­fices of congressmen who are re­sponsible for health legislation and ap­propriation.Dr. Jay Berke/hamerDr. John D. Burrington, Professor inthe Department of Pediatrics and head ofthe Section of Pediatric Surgery, pre­sented a paper entitled "The PediatricBurn Patient", sponsored by WylerChildren's Hospital at the Center forContinuing Education, May 1-2. At thesame meeting Dr. Peter R. Huttenlocher,Professor in the Department of Pediat­rics and Neurology, presented a paperentitled "The Child with NeurologicalProblems, Effects on the Family", andDr. Janis Mendelsohn, Assistant Pro­fessor in the Department of Pediatricsand Director Emergency Room, pre­sented a paper entitled" Possible Conse­quences of Disturbed Parent-InfantBonding" .Dr. Robert Chilcote, Assistant Pro­fessor in the Department of Pediatrics,was reappointed to the Board of Direc­tors and the Professional EducationCommittee of the American Cancer So­ciety Illinois Division. Pharmacological and PhysiologicalSciencesAppointment:Dr. Eric Schwartz-Assistant Pro­fessor.Dr. Leon I. Goldberg, Professor in theDepartments of Pharmacological andPhysiological Sciences and Medicine andChairman of the Committee on ClinicalPharmacology, was awarded the hon­orary degree of Doctor of Humane Let­ters from the Medical University ofSouth Carolina on June I. Dr. Goldbergreceived M.S. and Ph.D. degrees fromthe Medical College of South Carolina.PsychiatryAppointmen ts:Dr. Samuel E. Goldman (,75)­Ass istant Professor.Dr. Allen I. Kodish-Assistant Pro­fessor.Dr. Bennett L. Leventhal-AssistantProfessor.Dr. Robert Kahn, Associate Professorin the Department of Psychiatry, wasappointed a member on the Special Re­view Committee for Mental Health andAging at the National Institute of MentalHealth.Dr. Charles R. Schuster, Professor ofPs ych iatry and Pharmacological andPhysiological Sciences and the College,was named chairperson of the ExpertAdvisory Panel on Drug Dependence ofthe World Health Organization (WHO)this past fall.At a week-long meeting in Geneva, thepanel prepared official recommendationsfor the WHO for its role in implementingthe 1971 Vienna Treaty on PsychotropicSubstances. This treaty provides for thescheduling of psychotropic drugs intofour classes in terms of their medical use­fulness and their abuse potential.SurgeryDr. George E. Block, Professor in theDepartment of Surgery, was awarded theEdwin S. Hamilton teaching award bythe Illinois State Medical Society at itsannual meeting in Chicago. The award issponsored by the Interstate Post­graduate Medical Association of NorthAmerica (lPMANA).Dr. Martin J. Cooper, Research As­sociate (Instructor) in the Department ofSurgery, was awarded First Prize in theannual resident/fellow competition of theChicago Society of Gastroenterology forhis work on "Mechanism of SalicylateCholeresis in Rhesus Monkeys". Dr.Colin R. Mackie, Research Associate(Instructor) in the Department ofSurgery, was awarded Second Prize for41his evaluation of ultrasonography of thepancreas. Both doctors performed theirresearch in the laboratory of Dr. A. R.Moossa, Professor of Surgery, in collab­oration with Dr. James Bowie, AssistantProfessor in the Department of Radiol­ogy, and Dr. Alfred Baker, AssistantProfessor In the Department ofMedicine.Dr. Stuart J. F. Landa, Associate Pro­fessor in the Section of Plastic and Re­constructive Surgery, was elected Pres­ident of the Chicago Society of PlasticSurgery, Dr. Landa also is Treasurer ofthe American Society of MaxillofacialSurgeons and is a member of the Boardof Governors of the Midwestern Associ­ation of Plastic Surgeons.Dr. David B. Skinner, The Dallas B.Phemister Professor and Chairman of theDepartment of Surgery, was installed as the 39th President of the Society of Uni­versity Surgeons at its annual meeting inLouisville, Kentucky.He also was elected vice-president ofthe International Society for ArtificialInternal Organs; previously he served asPresident of the American Society forArtificial Internal Organs.Lr. Skinner was appointed to the As­sociation of American Medical College(AAMC) Task Force on Biomedical Re­search, which is preparing a positionpaper for the upcoming congressionalhearings.During recent months Dr. Skinner hasgiven invited lectures for the DenverAcademy of Surgery, the Grand RapidsSurgical Society, the annual Naffzigerlecture at the University of California atSan Francisco, and the William Beau­mont lecture to the Wisconsin SurgicalSociety. Dr. A. R. Moossa, served as a VisitingProfessor at the University of Liverpooland Leeds, England. He delivered fac­ulty lectures on pancreas cancer, bileduct injuries and inflammatory boweldisease.Dr. Moossa also participated at anInternational Symposium at the Liver­pool Medical Institution on "Recent Ad­vances in Liver Disease." He performedselected operations at both Universityhospitals.Dr. Moossa was appointed ExternalExaminer in Surgery at the University ofDundee in Scotland.Dr. Martin C. Robson, Professor in theDepartment of Surgery and Head of theSection of Plastic and ReconstructiveSurgery, was elected vice president ofthe Chicago Society of Plastic Surgery atits annual business meeting.Alumni News1935Sam W. Banks writes that he has been inSun City, Arizona for 6\12 years. After sixmonths there his practice in orthopedicsurgery almost equaUed the large prac­tice he formerly had in Chicago.Willard G. DeYoung is "enjoyingevery minute of a full-time private prac­tice in internal medicine at Illinois Cen­tral Community Hospital-enjoy theteaching of interns."1938Charlotte G. Babcock has received thetitle of professor emeritus of psychiatryfrom the University of Pittsburgh Schoolof Medicine. She writes, "1 am mostgrateful for my years of experience at theUniversity of Chicago. They offered meexcellent preparation for the nowtwenty-four years of work with and forthe University of Pittsburgh."Herman M. Serota advised us that hewas appointed clinical professor of psy­chiatry at the University of California,San Diego Medical School, where hecurrently is a training analyst of the SanDiego Psychoanalytic Institute. He alsohas a private practice in psychoanalysisin La Jolla.1943-MarchRobert R. Bigelow, general surgeon inOak Ridge, Tennessee, said in his classmessage. "Send my regards and inviteany of the class to visit me if in this partof the country."G. Campbell Cutler is in family prac-42 tice and assistant clinical professor ofmedicine at Michigan State College. Hismessage was, "Have always been proudof the U. of C. and remain so."Grace Baker Goebel telephoned theMedical Alumni Office with her message:.. After twelve years of a successfulpediatrics practice in Marin County,California, I received my masters degreein public health from the University ofCalifornia at Berkeley. Since then I havebeen a medical consultant with theCalifornia State Department of Health.The past eight years have been spent inthe license and certification divisionworking with hospitals and clinicsthroughout the State on federally fundedprograms. Husband, Jim, is chief ofurology at the Public Health Hospital inSan Francisco as well as in private prac­tice in Marin County. Daughter, Camille,is a marine biologist, and son, Jim, sailedon the tall ships last year."Paul Hohm, surgeon in Huron, SouthDakota, and father of two physiciansons, sent this greeting," Keep turningout those fine M.D.'s."Arthur Loewy, professor of otolaryn­gology at the University of Illinois Abra­ham Lincoln School of Medicine, whoalso has a private practice, wrote: "Ihave just returned from a second trip tothe Peoples Republic of China and nolonger have doubts about acupunctureanesthesia. Remainder of the tripsequally exciting."Donald McIntyre, clinical associateprofessor of obstetrics-gynecology at theUniversity of Washington Hospital inSeattle, wrote, "I am proud of our medi­cal school. My instruction in school was excellent. 1 hope the progress con­tin ues. "Edward Robbins is practicing in SanFrancisco where he is associate clinicalprofessor of medicine at the Universityof California and associate chief ofmedicine at Mt. Zion Hospital.1943--DecemberTed R. Mafit of Roseburg, Oregon, listshis specialty as wine maker (HumbugWinery, Bonded Oregon #65) and asksthe readers to drink more Oregon va­rietal wine'Shirley A. Mayer writes that she hasappointed herself as a committee of oneto find Sue Foss. Dr. Mayer is at the Co­lumbia University School of Medicineand Columbia University School of Pub­lic Health and Administrative Medicine.John Plunkett continues with his workat Yale University and the private prac­tice of psychoanalysis. "During the pastyear I have become more involved withthe Western New England Institute ofPsychoanalysis as a training analyst andas a member of its education commit­tee." Dr. Plunkett is associate clinicalprofessor of psychiatry at Yale and di­rector of training and clinical services atthe University Health Department.LaRele Stephens is in "semi­retirement" working eight hours per dayat the Eastern State Hospital in MedicalLake, Washington. "Am enjoying work­ing with the mental patients of Eastern.My undergrad work in college was inpsychology and I spent a year working atthis hospital before going to Chicago formedical school. Have maintained inter­est in mental health work while in privatemedicine for 26 years in Moscow, Idaho.Came to Spokane and Medical Lake 4V2years ago and will continue here until Iwish to fully retire. Thanks greatly forthe list of my class with their addressesVelma and I send greetings to all."1946David B. Clark received the John B.Hower Award of The Children's Hospi­tal Medical Center of Akron (Ohio) forexcellence in the field of PediatricNeurology. Dr. Clark is professor andchairman of the Department of Neurol­ogy at the University of Kentucky Medi­cal Center, as well as professor of pediat­rics. Dr. Douglas N. Buchanan, Pro­fessor Emeritus at The University ofChicago, was the first recipient of thisaward. associate clinical professor of psychiatryat the University of Illinois College ofMedicine and executive director of theRock Island (Illinois) Community MentalHealth Center.1948Bob Adamson couldn't make the classreunion because he was in France.Ernst Jaffe regretted he couldn't jus­tify another trip to Chicago (after attend­ing the 50th Anniversary celebration) butadded, "I would love to be able to attenda reunion of the class of 1948. I recentlyhad the pleasure of visiting with Dottyand Bob Adamson in San Francisco andI see Jay Seegmiller, Dick Blaisdell andBob Jim occasionally." Dr. Jaffe has'"retired" as editor-in-chief of Blood,Dr. Max E. Criffin ('46), director of Ambulatory Patient Services; Children's Hospital Center ofAkron (left), with Dr. David B. Clark ('46), at award presentation.Laurence Finberg was elected pre­sident of the American Board of Pediat­rics for 1978. Dr. Finberg is professor ofpediatrics at the Albert Einstein Schoolof Medicine in New York.1947Robert M. Chanock, chief of the Labora­tory of Infectious Diseases of the Na­tional Institute of Allergy and InfectiousDiseases, delivered the 27th annual Dyerlecture on May 31 at the National In­stitutes of Health. The lecture wasestablished in 1950 in honor of the lateDr. Rolla E. Dyer, and the lecturer isselected from among scientists who havemade important contributions in medicalor biological research, particularly in thefield of infectious diseases.Thomas Tourlentes has been serving aspresident elect of the American Associa­tion of Psychiatric Administrators. He is the journal of the American Society ofHematology.Allan Rosenblatt, director of the SanDiego Psychoanalytic Institute, is writ­ing with his colleague, Dr. JamesThickstun, parts 3 and 4 of their eight­part volume, Modern PsychoanalyticConcepts in a General Psychology.Parts I and 2 were published last Januaryas a Psychology Issues Monograph byI.U.P.Edyth Schoenrich missed the reunionas she had to attend alumni meetings atthe Johns Hopkins University School ofHygiene and Public Health where she isassociate dean.1950Dean Bahler is medical director at R. R.Donnelley & Sons in Crawfordsville, In­diana and through his company's giftmatching program is providing additional support to our Medical Alumni Fund.We thank you for this additional help.1953E. Russell Alexander sent this messagefrom Seattle: "We get lonely out in theNorthwest. Norm Breslow, Jean Priestand Wayne Akeson have been here andleft-why I don't know. Marjorie Wilsonis across the mountains. So I am alwayseager to see old friends." Dr. Alexanderis in the department of epidemiology atthe University of Washington School ofPublic Health.Alexander Ervanian hopes "that mostof us will be together for the 50th reun­ion." Dr. Ervanian is a pathologist inDes Moines, Iowa.Frank Fitch and his wife hosted a partyfor the Class of '53 after the MedicalAlumni dinner June 8. Pictured from leftto right at the Fitch's home are: Frontroll'. Paul Glickman, Ira Wool, MarvinWeinreb, Louis Cohen, and EdwardLyon. Back 1'011', John Thompson,Charles Johnson, Fred Matthies, MorrisSeide, and Frank Fitch.Harry Parks noted that" after 25 yearsit becomes more and more apparent tome how well schooled we were when welearned not only data (much of it nowobsolete) but the timeless will to con­tinue learning as life unfolds." Dr. Parksis certified in radioisotopic pathology bythe American Board of Pathology andthe American Board of NuclearMedicine.Marjorie Wilson writes from Yakima,Washington that she has been working as"medical director of the Yakima Neigh­borhood Health Services for low incomepeople. Husband is labor relations attor­ney and author of three books on laborrelations. "1954Nicholas T. Zervas has been appointedprofessor of surgery at Harvard MedicalSchool and chief of neurosurgery at theMassachusetts General Hospital. He is43currently working on the development ofa device to measure intracranial pres­sures by radio telemetric methods. Thisnon-invasive technique replaces a morecomplicated and more uncomfortableprocess for the patient.1955Arthur K. Shapiro last fall accepted anappointment as clinical professor of psy­chiatry and director of the Tourette andTic Laboratory and Clinic at the MountSinai School of Medicine, New York.Mrs. Elaine Shapiro (Ph.D. 1963) hasbeen appointed associate clinical pro­fessor of psychiatry (psychology) andco-director of the Tourette and Tic Lab­oratory and Clinic. They are co-authorswith R. D. Bruun and R. D. Sweet ofGilles de la Tourett e Syndrome, pub­lished in 1978.1957Robin Powell was named associate deanfor academic affairs at NorthwesternUniversity Medical School. Dr. Powellwas formerly on the University of Iowafaculty.1958Robert Barbee writes from Tucson wherehe is associate professor at the U ni ver­sity of Arizona College of Medicine:"Enjoying life in Arizona and lookingforward to a sabbatical this summer."Jerry G. Chutkow has been professorand chairman of the department ofneurology at the State University of NewYork, Buffalo School of Medicine, sincelast September.Richard H. Gier writes from Pocatello,Idaho that "he has had a private practiceand [has been) consulting in psychiatryin southeastern Idaho since July, 1977,after six years in Ohio."John T. McEnery is chairman of thedepartment of pediatrics at St. Anne'sHospital and assistant clinical professorof pediatrics at the Stritch School ofMedicine, Loyola University. He alsohas a private practice.Wendell F. Rosse is chief of thehematology-oncology division at DukeUniversity.Rick Singer has been in a group prac­tice of general and vascular surgery inSan Gabriel Valley, California for tenyears.Fred Solomon spends most of his timeconsulting at the Institute of Medicine ofthe National Academy of Sciences(lOM). He just finished coordinating andediting a group of 10M papers for thePresident's Commission on MentalHealth and is now serving as director of astudy of "appropriate use of sedative­hypnotics in medical practice."44 Charles S. Tidball is completing a sab­batical year at the National Institutes ofHealth where he has been consultant tothe deputy director of the Clinical Centerand has been developing a three-leveltraining program for physicians to learnhow to use a large patient managementcomputer system (Technicons MatrixMedical Information System).Richard Weinberg and CharlesAlexander are partners in a medicalbuilding in Springfield, Pennsylvaniawhere Richard practices dermatologyand Charles is an ophthalmologist.Sidney Wolfson, Jr. extends an invita­tion to classmates to get in touch withhim when in the Pittsburgh area for amini-reunion. Dr. Wolfson is professorof neurosurgery and associate professorof surgery at the University of PittsburghSchool of Medicine.1959Harvey W. Glasser was elected boardpresident of the Bay Area Rapid TransitDistrict (BART). Dr. Glasser is founderand president of California Health Ser­vices, a hospital consulting and man­agement firm, which manages eight hos­pitals and provides medical care to ele­ven communities in California andNevada.1960Sigmund Friedland is practicing internalmedicine and cardiology (board certifiedin both) as a partner of the DiagnosticClinic of Houston. He also is on theteaching staffs of the University of Texas(Houston) and Baylor College ofMedicine.Edward Weinshelbaum was selectedby the senior medical students at theUniversity of Florida to receive the 1978Hippocratic Award for Teaching Excel­lence. Dr. Weinshelbaum has recentlyestablished a private practice in generalsurgery in Gainesville, although he willmaintain his affiliation with the univer­sity as clinical associate professor insurgery and serve as a consultant withthe Gainesville Veterans AdministrationHospital. Dr. Arlene Weinshelbaum(1968) is assistant professor of radiologyat the University of Florida MedicalSchool. They have three children: Lisa,6; Karen, 3: and Michael, 2.1961We are pleased to announce that DennisWentz is taking over as class chairman.Dr. Wentz is assistant vice chancellor foracademic affairs at the University ofTennessee. We thank Roger Becklund,former chairman, for the wonderful ser­vices he has provided to the MedicalAlumni Office. 1962Leonard Lyon writes, "I currently dividemy professional time between privatepractice (cardiology and internalmedicine) and teaching. I am co-directorof medical education at the Bergen PinesCounty Hospital in Paramus, New Jer­sey, which is affiliated with the Collegeof Medicine and Dentistry of New Jerseyat Newark, where I am clinical associateprofessor of medicine." His book, BasicElectrocardiography Handbook, hasbeen published. Following the publica­tion of a paper on "Nontreatrnent of HipFractures in Senile Patients," (JAMA,238: 1175, Sept. 12, 1977) he was inter­viewed by Physicians Radio Network onhis methods.1963Robert C. Andruczk was promoted tothe rank of colonel in the US Air Force ata ceremony at Sheppard Air Force Base,(AFB) Texas in June. Colonel Andruczkis serving as chief of hospital services forthe USAF Regional Hospital at Shep­pard AFB. His wife, Ann, and ColonelJohn Funk, commander of the USAFRegional Hospital, presented him withhis new military insignia.Harold Bass has presented papers at theInternational Birth Defects Conferencein Montreal and at the American Societyof Human Genetics in San Diego. He isdirector of genetic services at theKaiser-Permanente Medical Center inPanorama City, California, and assistantclinical professor of pediatrics (genetics)at the UCLA School of Medicine.John Bonner continues as chairman ofcontinuing education and program com­mittee for the Fresno-Madera (Califor­nia) Medical Society. Dr. Bonner, aneurosurgeon, has authored a chapter on"Initial Care of Head and Spinal In­juries" in Immediate Care a/the AcutelyIII and Injured, 2nd edition, edited byHugh E. Stephenson, Jr.Gary Gitnick is associate professor ofmedicine at UCLA Center for the HealthSciences and director of thegastroenterologyiimmunovirology unit.His research interests include in­flammatory bowel disease and acute andchronic liver disease. He is the author of125 publications.Michael Kinney, currently with theUSPHS, writes, "In October I shall as­sume the responsibility for building anephrology division at a newlyestablished medical school. I will be as­sociate professor of medicine and chiefof the nephrology division at the Mar­shall University School of Medicine inHuntington, West Virginia, and chief ofthe nephrology service of the HuntingtonV.A. Hospital. I'm looking forward tothe challenge."Bernard Mizock is in general surgery atIllinois Masonic Medical Center(Chicago). He and his family recentlymoved into a new home in Skokie.Mark Silverman was promoted to pro­fessor of medicine (cardiology) at EmoryUniversity School of Medicine. He ispresident-elect of the Georgia Heart As­sociation.Marvin Stone is chief of oncology anddirector of immunology at Baylor Uni­versity Medical Center in Dallas, wherehe is director of Baylor's Charles A.Sammons Cancer Center. He also is clin­ical professor of internal medicine at theUniversity of Texas Southwestern Medi­cal School in Dallas. Dr. James W. WinebrightJames W. Winebright, a Navy com­mander, is now the head of the NuclearMedicine branch of the Naval RegionalMedical Center in Oakland, Calif. He isone of only four nuclear medicine physi­cians in the US Navy.Rostik Zajtchuk (center) receives his insignia, aided by his wife and their commander.Rostik Zajtchuk was promoted to col"onel in the US Army at a ceremony atWalter Reed Medical Center in Washing­ton, D.C. His new insignia was pre­sented to him by Major General GeorgeBaker, commander of Walter Reed Med­ical Center, and Dr. Joan Zajtchuk ('66),his wife. Rostik is on the thoracic serviceand Joan is on the otolargyngology ser­vice.1964James J. Castles has been appointed as­sistant dean for planning and develop­ment at the University of California,Davis School of Medicine. His re­sponsibilities include planning foracademic programs and physicalfacilities for the medical school. Dr. Cas­tles is associate professor of internalmedicine and chief of the section ofrheumatology.Carrie K. Schopf is director of admit­ting and the ambulatory care center atthe Lakewood Hospital in Lakewood,Ohio. 1965Wayne Janda writes he is an orthopedicand traumatic surgeon at Park Clinic inMason City, Iowa.Murray D. Kuhr was appointed full­time director of pediatrics for GoodSamaritan Hospital, Suffern (New York)last fall. His appointment coincides withthe hospital's affiliation with a majorNew York City teaching hospital for theeducation and services of pediatric resi­dents. He also is assistant clinical pro­fessor of pediatrics at Columbia Collegeof Physicians and Surgeons. An articleon "Neural-Tube Defects and Mid-CycleAbstinence: A Test of the 'Over­Ripeness' Hypothesis in Man" was pub­lished in Develop, Med. Child Neural.1977, 19,589-592.We couldn't let this go unreported.Nicholas Vick received the outstandingclinical teacher award last year atNorthwestern University MedicalSchool. Dr. Vick is head of the neurol­ogy division at Evanston Hospital andassociate professor of neurology. 1966Jay S. DeVore reports that he is assistantprofessor of anesthesiology andobstetrics/gynecology at the Universityof California, Irvine Medical Center anddirector of obstetric anesthesiology.Sidney Kadish advised that he has beenappointed associate professor of radiol­ogy at the University of MassachusettsMedical School in Worcester.Douglas R. White has been promotedto associate professor of medicine(hematology/oncology) at the BowmanGray School of Medicine of Wake ForestUniversity. He also is serving as co­chairman of the professional educationcommittee of the American Cancer Soci­ety.1968Bradley Hales has completed his re­sidency and entered private practice inotolaryngology in Butte, Montana. He isboard certified.Fitzhugh Mullan was appointed direc­tor of the National Health Service Corpslast October. Dr. Mullan and his wife,Judith, have three children: Meghan, 6:Jason, 4: and Caitlin, 2: who are "funand all encompassing."Jack Sipe visited the Medical AlumniOffice in June. His news is that he hasjoined the Scripps Clinic and ResearchFoundation as a consultant in neurology.He is associate clinical professor ofneurosciences at the University ofCalifornia at San Diego where he main­tains teaching and research activities.1969Carol Langford Robins writes that she isa pediatrician at Roxbury Dental andMedical Group (part-time) and has a MayC. Willett Fellowship in child neurologyat Children's Hospital in Boston.Robert Rubenzik advises that he isophthalmology editor of ArizonaMedicine, the state medical society jour­nal. Dr. Rubenzik practices in Phoenix.1972Robert Chevalier is a clinical nephrologyfellow in the department of pediatrics atthe University of Colorado Medical Cen­ter in Denver.Louis Constan has left private practiceto become associate director of the Fam­ily Practice Center in Saginaw, Michi­gan.Lucy and Eric Lester will be spendingthe next two years at the National In­stitutes of Health and will be living inGaithersberg, Maryland.Robert Ramsey has entered privatepractice in hematology-oncology in"beautiful" Medford. Oregon.Mary and Stephen Weinstein are ex-45pecting a second child in December.Mary is board certified in pediatrics andon the staff in neonatology at the Univer­sity ofIowa hospitals. Steve continues inhis urology residency.1973Richard W. Furlanetto was appointed as­sistant professor in pediatric endocrinol­ogy at the University of Texas MedicalBranch in Galveston.David A. Gilbert, acting instructor inmedicine at the University of Washing­ton Affiliated Hospitals, writes, "I amali ve and well with a horde of U. of C.medical alums in Seattle-Rick Berger,Chuck Chuman, John Harlan, BobKanter, Mary Pretzer, and Bill Truog."Robert Kirk began a plastic surgery re­sidency at the University of Kentucky inLexington in July.The following are at the National In­stitutes of Health in Bethesda:David Gordon is a project officer. Hisspecialty is lipid metabolism research:Rudiger Kratz is working under Dr. KingEngel on muscle membrane receptors inhuman dystrophies; Lee Leserman is aclinical associate in pediatrics: and Ken­neth McClain is a research associate inpediatrics and virology.Lois Anne Nelson is a fellow in pediat­ric allergy and immunology at the Uni­versity of Rochester, Strong MemorialHospital.Jean-Paul Pegeron, a psychiatrist atthe University of Michigan Hospitals,advised that he has been board certifiedin psychiatry and neurology.Theodore J. Pysher is a fellow inpediatric pathology at Children's Hospi­tal in Los Angeles.James E. Schwanke is in privatepediatric practice in San Francisco.Stanley Schwartz has been appointedto the faculty of the department ofmedicine at the University of Penn­sylvania, where he will be teaching andseeing patients on the diabetes service.He and his wife are the parents of aneight-month-old son.Jeffery Semel became head of the sec­tion of infectious diseases at St. JosephHospital (Chicago) and associate ininternal medicine at Northwestern Medi­cal School. He and his wife, Linda, havea son, Adam, one year old.Michael Silverman will enter privatepractice in rheumatology in Portland,Oregon in September.Mark C. Steinhoff is a fellow in infecti­ous diseases in the department of pediat­rics at the University of Rochester,Strong Memorial Hospital.Barry E. Wright completed a specialfellowship in retinal diseases and vitre­ous surgery at the Moorfields Eye Hospi-46 tal in London, England and was ap­pointed associate director of the RetinaService at Montefiore Hospital and Med­ical Center and instructor in ophthalmol­ogy at the Albert Einstein College ofMedicine in New York.1974Renee Szabo Band completed her re­sidency in pediatrics at Wyler Children'sHospital and Loyola Medical Center andhas been appointed to the emergencyprogram staff of Delnor Hospital in St.Charles, Illinois.Marc Graff completed his internshipand residency in psychiatry at the U ni­versity of Rochester, Strong MemorialHospital and has been appointed an as­sistant professor of psychiatry at theUniversity of Pittsburgh's Western Psy­chiatric Institute and Clinic.1975Harris Barowsky is entering private prac­tice of internal medicine in Pittsburgh.Charles Barsano is a fellow in endo­crinology at The University of Chicago.Gomez Charleston is a fellow in car­diology at Michael Reese Hospital inChicago.Francis Collins is a fellow in internalmedicine/endocrinology in Columbus,Ohio.John Danielson is chief resident inENT at The University of Chicago andwill be chief resident in plastic surgery1979-1981.Marion Danis is an instructor in gen­eral medicine at North Carolina Memo­rial Hospital in Chapel Hill.Ronald J. Fitzgerald is chief resident inpsychiatry at Northwestern MedicalSchool.Howard Forster has entered privatepractice in internal medicine in Meriden,Connec tic ut.Mary Ellen Gaeke is a fellow in internalmedicine and hematology/oncology atThe University of Chicago.Victor German is a fellow in pulmo­nary and neonatal medicine at the Uni­versity of California, San FranciscoMedical Center.Edbridge Holland is in family practiceat the Island Medical Center in Chin­coteague, Virginia.Lisa Kaplowitz is a fellow at the Uni­versity of North Carolina.James Kessel is in private practice inobstetrics/gynecology in St. Louis.Jeffrey Kraines is an attending physi­cian at Michael Reese Hospital, Chicago.Ross Lambert, Jr. is assistant directorof rehabilitative engineering, researchand development at Hines Veterans Ad­ministration Hospital, Maywood, Il­linois. Robert Lawton is a staff psychiatrist atthe West Side V.A. Hospital and assis­tant professor of psychiatry at the Uni­versity of Illinois.Joseph Locker is assistant professor inthe department of pathology at The Uni­versity of Chicago.John Low is in private practice ofinternal medicine in San Francisco.John Milley is a neonatology fellow atJohns Hopkins Hospital.Terence O'Connor is attending physi­cian in anesthesiology at The Universityof Chicago.Richard Pauli is a fellow in pediatricgenetics at Children's Orthopedic Hospi­tal in Seattle.Robert Quaas is practicing pediatricsin St. Louis.Robert Sanford is a fellow in gastroen­terology at the University of Washing­ton.David J. Schanzlin is a corneal diseasefellow in Pittsburgh.Richard Schilsky is a clinical associateat NIH in Bethesda.Bruce Schreider is a fellow in clinicalpharmacology at The University ofChicago.David Scollard is a lecturer in the de­partment of pathology at the Universityof Hong Kong.Michael Serwint is a fellow in oncologyat the University of Kentucky.John Scholl is a fourth year resident inobstetrics/gynecology at the Universityof Chicago.Alan Smith is head of internal medicineat the Medical Center of Gary (Indiana).James Soderberg is a pediatrician withthe Permanente Medical Group in SanJose, -California.Melvyn Sterling is an assistant clinicalprofessor in internal medicine at theUniversity of California, Irvine MedicalCenter.James Stewart is an instructor inmedicine at the Medical College of Vir­guua.John Strausser is senior staff in­vestigator at the National Cancer I n­stitute, Bethesda.Bruce Wainer is assistant professor inpathology at The University of Chicago.Wai-Kwan Yung is a fellow in the de­partment of neurology at Memorial SloanKettering Cancer Center in New York.Susannah Walker is an instructor inpediatrics at St. Louis Children's Hospi­tal.1978For three members of this year'sgraduating class, Medical Alumni Dayhad a double meaning. Charles GroverGabelman, III, Cary Stephan Keller andTwo generations of medical alumni: (Seated, from left to right) Ms, Irene Baucom, Charles C,Cabelman Ifl (78), Dean L. Rider If ('78), and Mrs, Dale Rider. (Standing from left to right) Dr,Charles C. Cabelman If ('44), Mrs, Charles Cabelman, Dr, J, Alfred Rider ('44), and Mrs, I,Alfred Rider,Dean Loller Rider II and their fathers areall alumni of the medical school.Former StaffPaul Agnew (Psychiatry, '56-'78) was ap­pointed clinical director at the La PorteCounty (indiana) Mental Health Center.He is the first board-certified psychiatrist'to serve at the Center.Jayme Borensztjan (Pathology, re­search associate (instructor), '70-'72: as­sistant professor, '75-'78) accepted a po­sition at the Northwestern UniversityMedical School in the department ofpathology.H. Close Hesseltine (Obstetrics, fac­ulty, '34-'64) and Huberta M. Livingstone(General Surgery-Anesthesiology, fac­ulty, '28-' 52) continue as members of theExecuti ve Committee of the AmericanRetired Physicians Association.Lewis L. Kramer (Dermatology, resi­dent, '72-'75) works in the DermatologyClinic at the Kaiser Foundation Hospi­tal, Fontana, California 92335.Robert D. Moseley, Jr. (Radiology,resident, '50-'54; professor and chair­man, '54-'71) was appointed chairman ofthe department of radiology at the U ni­versity of New Mexico. Dr. Moseley hasbeen a member of the medical facultysince 1971 and has been serving as actingchairman.Dr. Moseley was selected last yearfrom all American radiologists to serve asthe annual orator of the RadiologicalSociety of North America. He serves asthe U.S. representive to the United Na­tions scientific committee on the effectsof atomic radiation, and is chairman of Dr, Robert 0, Moseley, ir.the U.S. delegation to the InternationalCongress of Radiology in Rio de Janeiro.Suzanne Oparil (Medicine, assistantprofessor, '72-'75; associate professor,'75-'77) accepted a position in the de­partment of medicine at the University ofAlabama Medical School, Birmingham.Christian Rieger (Pediatrics, resident,'70-'74: assistant professor, '74-'76) re­sides in Germany as a Privatdozent atthis address: Kari-Wiechert-Allee 9, 3Hannover 61, Fed. Rep. of Germany,Telephone: 0511153 23 220.Mitchell L. Rhodes (Medicine,resident/feUow, '66-'70; instructor, '70),associate professor in the department ofmedicine at the Indiana University Med­ical Center, Indianapolis, Indiana, iscoauthor of a book entitled ChronicObstructive Lung Disease.' Its ClinicalManagement and Treatment, publishedby C. V. Mosby and Co. Peter Rosen (General Surgery, as­sociate professor and directoremergency room, '71-'73): professor anddirector emergency medicine, '74-'77)was appointed associate director of thedepartment of emergency medicine atthe Denver General Hospital.Natalia M. Tanner (Pediatrics, intern,, 46-' 4 7), clinical associate professor,Adolescent Services in the department ofpediatrics at the Wayne State Universityand Children's Hospital of Michigan, re­ceived the following prestigious awardsin 1977. Distinguished Alumnus Awardfor outstanding achievements inmedicine from Meharry Medical College,Nashville, Tennessee: State of Michigan,Governor's Certificate of Merit Award inrecognition of exceptional achievement,outstanding leadership, citizenship,scholarship and dedication to improving'the quality of life for all humanity: Spiritof Detroit, Mayor's Award in recognitionof exceptional achievement, outstandingleadership and dedication to improvingthe quality of life.Dr. Tanner presented a paper entitled"So What's New? Health Maintenanceof the Adolescent" at the Orientation toAdolescent Care, sponsored by Chil­dren's Hospital of Michigan, Detroit,May 10-12.Eric J. Udoff (Radiology, intern/resident, '73-'77) is an instructor/fellowin cardiovascular radiology at the JohnsHopkins Hospital, Baltimore, Maryland.John W. Weiss (Dermatology, resi­dent, '60-'63), clinical professor ofmedicine and chairman of the section ofdermatology at Loyola UniversityStritch School of Medicine, was co­chairman of a postgraduate course,sponsored by the American Academy ofDermatology and Clinical Dermatology,entitled Recent Advances inPathogenesis and Treatment, held inChicago. Dr. Weiss spoke on .. AcneVulgaris" and led a symposium on thesubject.Victoria Wellman (Anesthesiology,resident), now practicing in Cobourg,Ontario, Canada, at the time of theQueens Silver Jubilee visit was pre­sented with a Silver Jubilee medal for herwork at the Cobourg Hospital and thecontributions she had made to the com­munity.Divisional Alumni NewsDr. Donald V. Coscina (Biopsychology,Ph.D. '71) was appointed head of thenew section of biopsychology research atthe Clarke Institute of Psychiatry in To­ronto, Canada. The researchers will de­sign and perform experiments with ani­mals which will promote better under-47standing of behavioral and biological fac­tors in human mental illnesses.Leonard Hamilton (Biopsychology,Ph.D. '68), associate professor andchairman in the department of psychol­ogy at Rutgers University, NewBrunswick, New Jersey, is author ofBasic Limbic System Anatomy of theRat, Plenum Press, 1977. He is acoauthor of Learning and Memory,Rand-McN ally, 1976.Dr. Roger H. Scholle (Pathology, M.S.'67) was appointed editor of the Ameri­can Dental Association. He will directthe Association's scientific publicationsand will be editor-in-chief of all journalsof the Association.Since 1973 he has been a member ofthe Panel of Review of OTC Dentrifricesand Dental Care Agents of the U.S. Foodand Drug Administration. He also serveson the board of directors of the IllinoisDivision of the American Cancer Societyand is an active member in many organi­zations.Dr. Scholle has a part-time privatepractice in Chicago and also is on thepart-time staff at Northwestern Univer­sity Dental School.American College of Physicians FellowsThe following alumni were inducted asfellows in the American College ofPhysicians at the November, 1977 andApril, 1978 meetings:Paul T. Davidson ('62), Denver, Col­orado; Jack L. McCleery ('62), Han­nover, New Hampshire; Jon P. Gocker­man ('67), Lexington, Kentucky; DanielJ. Hurst ('67), Columbia, Missouri;Franklin Kozin ('69), Fox Point, Wis- consin; and Henry W. Ryder ('37), Cin­cinnati, Ohio.Class Chairmen Cited forBest Fund raising Year YetClass chairmen were honored at theMedical Alumni Day breakfast on June 8for their efforts in leading the most suc­cessful 1977 Medical Alumni FundDrive. Dean Robert Uretz hosted thisannual breakfast in honor of the CenturyClub members and the class chairmen.Fifteen class chairmen attended thebreakfast:Vida Wenz, '35Leon Jacobson, '39Stewart F. Taylor, '45 (Wisconsin)Henry DeLeeuw, '47 (Michigan)Asher J. Finkel, , 48Mary D. Carroll, '49 (Indiana)Benjamin Spargo, '52Frank Fitch, '53Sumner C. Kraft, , 55Walter B. Eidbo, , 56 (Iowa)Everett H. Given, , 59 (California)Dennis Wentz, '61 (Tennessee)Rostik Zajtchuk, '63 (Maryland)Julian Rimpila, '66Richard F. Gaeke, '73Dr. Dennis Wentz is the new chairmanfor the class of 1961, replacing Dr. RogerBecklund, who had served for severalyears. Dr. Wentz is assistant vice chan­cellor for academic affairs at the Univer­sity of Tennessee.The 1977 fund raised a total of $715,915 in gifts and bequests. This is thelargest amount ever reported. Thirty-twopercent of the alumni participated in thefund.The following alumni received specialrecognition for their achievements andwere presented a copy of the book,Dreams in Stone, which features photo­graphs of The University of Chicago:Dr. Vida Wentz, '35, whose class forthe second year achieved 65 percent par­ticipation, the highest of any class.Dr. Henry DeLeeuw, '47, whose classraised the most money for the fund. Hisclass raised $8,380 with 54 percent par­ticipation. Dr. Daniel Black, '47, offeredto match all new or additional gifts, sothe class total reached $11,800.Dr. Eli Borkon, '37, for the class withthe greatest improvement. His classjumped from 39 percent to 54 percentparticipation.Included in the 1977 fund year werebequests of $294,000 from the estate ofDr. Harold L. Thompson, Rush '23 toestablish the Sara and Harold LincolnThompson Professorship of Gastroen­terology and $100,000 from the estate ofDr. David Levy, Rush, '19.In 1977 two medical student loan fundswere established: the Smith-Regan Med­ical Student Loan Fund was establishedby gifts from The Foley Medical Founda­tion, Inc. whose directors are KendrickSmith, '37 and James F. Regan, '34. TheMarc Dudnikov Memorial Loan Fundwas established by Mr. and Mrs. Mitch­el! Dudnikov and friends of Marc, whowould have been a member of the classof 1979.48 Dean Robert B. Uretz and his staff: (leftto right) Mr. John Piva, Assoc.Vice-Pres. of Med. Center(Development); Dr. Jarl Dyrud, Assoc.Dean for Faculty Affairs; Edwin Taylor,Ph.D., Assoc. Dean Div. Bioi. Sci.Collegiate Div.; Dr. Frank Fitch, Assoc.Dean for Educational Affairs; JosephCeithaml, Ph.D., Dean of StudentsDiv. Bioi. Sci, and Pritzker Sch. ofMedicine; Mr. David Bray, Assoc.Vice-Pres. for Med. Center(Administration); Dean Robert B.Uretz; Ms. Joan Mendelsohn, formerAssoc. Dir. Cancer Control Center; Dr.John Ultmann, Assoc. Dean forResearch Programs; Dr. J. RobertBuchanan, Assoc. Dean for MichaelReese Programs; Mr. Jeff Goldsmith,Dir. Health Policy Analysis; Mr. EdWard, lr., sitting in for Mr. JohnDorfmeister, Dir. of Business andFinance (Academic Affairs), Div. Bioi.Sci. and Pritzker Sch. of Medicine; andMr. Gary Campbell, sitting in for Mr.Nels Berg, Dir. for Plant and Facilities,Mgmt. Med. Center.1935Dr. Vida B. WentzApartment 13-A5820 Stony I sland A venueChicago, Illinois 606371936Dr. John P. FoxUniversity of WashingtonSchool of Public Health and CommunityMedicineDepartment of Epidemiology andInternational HealthSeattle, Washington 981951937Dr. Eli L. BorkonDoctors Memorial Hospital404 West Main StreetCarbondale, Illinois 629011939Dr. Leon O. JacobsonThe Franklin McLean MemorialResearch InstituteThe University of Chicago950 East 59th StreetChicago, Illinois 606371943 (Class of March)Dr. Charles P. McCartney12412 South 74th AvenuePost Office Box 605Palos Heights, Illinois 604631943 (Class of December)Dr. W. E. FroemmingTeletype Corporation5555 Touhy AvenueSkokie, Illinois 600761945Dr. Stewart F. Taylor116 E. Pleasant StreetPortage, Wisconsin 539011946Dr. Edward R. Munnell8601 North GeorgiaOklahoma City, Oklahoma 731141947Dr. Henry DeLeeuw4090 Highgate RoadMuskegon, Michigan 494411948Dr. Asher J. FinkelAmerican Medical Assoc.Scientific Affairs ContinuingMedical Studies535 North Dearborn StreetChicago, Illinois 606101949Dr. Mary D. Carroll124 N. Main StreetCrown Point, Indiana 463071950Dr. Abbie R. Lukens CLASS CHAIRMEN87th and County Line RoadHinsdale, Illinois 605211951Dr. Arnold L. Tanis925 North Northlake DriveHollywood, Florida 330191952Dr. Benjamin H. SpargoUniversity of ChicagoDepartment of Pathology950 East 59th StreetChicago, Illinois 606371953Dr. Frank W. FitchThe University of ChicagoDepartment of Pathology950 East 59th StreetChicago, Illinois 606371954Dr. Dorothy WindhorstHoffmann-LaRoche Inc.Research DivisionNutley, New Jersey 071101955Dr. Sumner C. KraftUniversity of ChicagoDepartment of Medicine950 East 59th StreetChicago, Illinois 606371956Dr. Walter B. Edibo3201 Wauwatosa DriveDes Moines, Iowa 503211957Dr. Francis H. Straus, IIUniversity of ChicagoDepartment of Pathology950 East 59th StreetChicago, Illinois 606371958Dr. Gerald Paul Herman8224 Mentor A venueMentor, Ohio 440601959Dr. E. H. Given149 E. Palm Lane DriveRedlands, Calif. 923731960Dr. Randolph W. SeedGrant Hospital551 Grant PlaceChicago, Illinois 606141961Dr. Dennis K. Wentz3411 Waynoka AvenueMemphis, Tennessee 381111962Dr. Joseph M. BaronUniversity of ChicagoDepartment of Medicine 950 E. 59th StreetChicago, Illinois 606371963Dr. Rostik Zajtchuk, COL, MC8236 Windsor View TerracePotomac, Maryland 208541964Dr. Daniel PaloyanGlenbrook Hospital2100 Pfingsten RoadGlenview, Illinois 600251965Dr. Robert G. Hillman465 St. Michaels DriveSanta Fe, New Mexico 875011966Dr. Julian J. RimpilaSuite 406, Lake Point Tower505 North Lake Shore DriveChicago, Illinois 606111967Dr. Andrew J. Griffin834 W. Chalmers AvenueChicago, Illinois 606141968Dr. Burr EichelmanWaidman Center2605 Marsh LaneMadison, Wisconsin 537061969Dr. Andrew J. AronsonUniversity of ChicagoLa Rabida Children's Hospital andResearch CenterEast 65th Street at Lake MichiganChicago, Illinois 606491972Drs. Eric and Lucille Lester12335 Pueblo RoadGaithersberg, Maryland 207601973Dr. Richard F. GaekeUniversity of ChicagoDepartment of MedicineChicago, Illinois 606371974Drs. John and Pamela GallagherApartment 15-A435 East 70th StreetNew York, New York 100211975Dr. Maga Jackson3400 Vinton A venueApt. 207Los Angeles, California 900341976Dr. David HallDepartment of PediatricsJohns Hopkins HospitalBaltimore, Maryland 2120549QuestionnairesResponses to The University of Chicago medical alumnisurvey are assisting the Medical Center acquire a greaterunderstanding of alumni sentiment. You are the sourceof this information.If you have not already done so, please take the time tocomplete and return the questionnaire. In the event thatyou did not receive the questionnaire, or if it was mis­placed, we would be happy to send you another copy.Send your request, including your name and address to:Medical Alumni AssociationUniversity of Chicago1025 East 57th StreetChicago, Illinois 60637The results of the survey will be published in an up­coming issue of Medicine on the Midway.50 CalendarWednesday, October 18Reception for alumni andspouses during the AmericanCollege of Surgeons Meeting inSan Francisco, FairmontHotel, 5:30-7: p.m.Friday, December 8 (Tentative)Reception for alumni andspouses during the AmericanMedical Association Meetingin Las Vegas, 5:30-7:00 p.m.Frontiers of Medicine *October 25 (3 hours)Clinical EndocrinologyNovember 8 (6 hours)Environmental Emergenciesand Mass Casualty DisastersDecember 6 (3 hours)Organ Transplantation* A continuing medical educa­tion program granting hour­for-hour credit in Catgeory lofthe Physician's RecognitionAward of the American Medi­cal Association.Medicine on the MidwayThe University of ChicagoThe Medical Alumni AssociationThe Pritzker School of Medicine1025 East 57th StreetChicago, Illinois 60637 NON·PROFIT ORG.u.s. POSTAGEPAIDPERMIT NO. 9666CHICAGO, ILL.•Address corrections requestedreturned postage guaranteedThe JQSQph Regenstein LibrarySerial Records Department. Room-2221100 East 57th StreetChicago. Illinois 60637