C AGOBelUe/iu, 0/ lite AIumnI·A�ation5CI-IOOL'OF MEDICINEN V E R S·Volume 1 T Y o F C H. Number 8JULY 1945ANNUAL ALUMNI MEETING HELDThe annual reunion of the AlumniAssociation of the University of ChicagoSchool of Medicine was held June 13.During the morning the operating-rooms,clinics, and ward rounds were availablefor any who wished to participate. Thescientific session was scheduled between2: 00 and 5: 00 P.M. in Path. II 7. Therewas a good attendance at this meeting,and the masterful technique of the pre­siding officer, Dr. Leon Jacobson, 'inbringing the program of twelve papersto a close at the stroke of 5: 00 P.M. hasset a new.precedent in the managementof scientific programs. The followingpapers were presented:"The Mechanism of Citrate Intoxication,"THOMAS THORNTON, M.D."Urinary 17-Ketosteroids in the Diagnosis ofAdrenal Cortical Carcinoma," WILLIAMW. SCOTT, M.D."Studies on the Psittacosis Group of Viruses,"F. B. GORDON, M.D."Locomotion Characteristics of White BloodCells," P. P. H. DEBRUYN, M.D."Some Problems in the Diagnosis of Brucel­losis," C. W. EISLE, M.D."Gelatin Sponge: A New Absorbable Hemo­static Agent," JAMES CLARKE, M.D., andH. P. JENKINS, M.D."Excretion of Antibodies in Feces of Immu­nized Animals," WILLIAM BURROWS,Ph.D."Observations on the Etiology and Treat­ment of Polycythemia rubra vera," PAULW. SHAFER, M.D."The Significance of the Presence of QJ andInverted TJ in Clinical Cardiography,".CHAUNCEY MAHER, M.D."Experimental Studies of Pigmentation ofEndocrine Origin," M. E. DAVIS, M.D."Treatment of Generalized Peritonitis Com­plicating Ulcerative Colitis," W. E. RICK­ETTS"M.D., and W. L. PALMER, M.D."Diabetes in a Totally Depancreatized Man,"H. T. RICKETTS, M.D.The executive session of the Associa­tion was called to order by PresidentVictor Johnson at the close of the scien­tific program. After the reading of theminutes and the report of the secretaryby Dr. H. P. Jenkins, the treasurer's re­port- was then submitted by Dr. JohnVan Prohaska. Total receipts were $2,503,of which $2,072 was not expendible be­cause it was derived from life-member­ships, Endowment Fund, and advancepayment of dues. This left $431 avail­able from this year's annual dues for cur- rent expenses, which thus far have been$315.55, leaving $II5.45 available for thesecond issue of the BULLETIN, which hasbeen billed in the amount of $303.74.'Efforts have subsequently been made tomeet this deficit of $188.29 by an appro­priation to the, association from the Medi­cal School. The treasurer announced that$1,500 from life-memberships had beenturned over to the Treasurer of the Uni­versity of Chicago and invested in SeriesG War Savings Bonds, the interest onwhich will be made available to the Asso­ciation for current expenses.Dr. Gordon made a brief report on theBULLETIN, which obviously has "spokenfor itself." The report of the auditingcommittee was made by Dr. Ricketts andDr. Bensley to the effect. that the ac­counts of the treasurer were found to bein order; The members of the program- committee-Drs. Palmer, Loosli, andJacobson-were officially complimentedfor the excellence of the scientific program.The nominating committee-Drs.Wright Adams, Mullins, and Wentz-'made the following recommendations:for president, Victor Johnson; for vice­president, Peter Moulder; for treasurer,John Van Prohaska; for secretary, HilgerPerry Jenkins; for members of the coun­cil (to serve three years), Henry Rickettsand William Tucker. There was no re­sponse to requests for further nomina­tions and the candidates were unani­mously elected.Dr. Alfred Rider, the retiring. vice­president of the Association and secretaryof the Class of 1944, made a brief reporton behalf of his class. He proposed thename of Dr. Barbara Kinyon to carry onthe work of his class as Senate Repre­sentative, as he was expecting an assign­ment to active duty in the Army. Thiswas unanimously approved. (The Classof 1944 deserves special mention for itshelp in the reactivation of the Associationby sponsoring the Reunion-a year ago, bypublishing the first Yearbook, and by es­tablishing the first Endowment Fund forthe Association. The Association paystribute to the Class of 1944.)The graduating class proposed thename of Warren Wilhelm for their SenateRepresentative, and this was unani­mously approved. The meeting' was thenadjourned. 50th A nniversary Ifor Lying-in Hospital1945 marks the fiftieth year for theChicago Lying-in Hospital. The accom­plishments during this half-century inthe development of modern obstetrics,'in, its service to mothers and babies, ineducation, and in research have won anenviable place for this institution. Todayit ranks among the great obstetrical hos­pitals of the world.To celebrate this noteworthy event ':'and to do honor to the illustrious founderof the institution, Joseph B. De Lee, aninteresting program has been arrangedfor October 29, 1945. The staff of theDepartment of Obstetrics and Gyne­cology will take part in operative clinicsduring the morning: A number of in­vited guests will present papers in theafternoon. An instructive program innursing education will be presented byinvited guests from the nursing field. Abanquet has been arranged for the eve­ning, at which time Robert M. Hutchins,President of the University of Chicago,will be the principal speaker.The staff of the hospital hopes thatmany of our alumni and friends can par­ticipate in this celebration.GRADUATION BANQUETThe banquet in honor of the Gradu­ating Class of 1945 was given by theSchool of Medicine at the WindermereEast Hotel. Dr. Paul Hodges did a mostdelightful job as master of ceremonies.He presented Peter Moulder, president ofthe graduating class; Dr. Victor Johnson,president of the Alumni Association; andDr. M. Edward Davis, of the faculty.They spoke on behalf of their respective"constituents .. " The banquet was honoredby the presence of Mr. Harold Swift,President of the Board of Trustees of theUniversity, who is known to many as the"best friend" of the Hospitals and Medi­cal School. Following the introductionof Mr. Swift, the speaker of the evening,President Robert Maynard Hutchins,was then presented. His excellent speechwill be presented at least in abstract inone of the subsequent issues. The com­mittee on arrangements, under the leader­ship of Dr. Palmer, deserves much creditfor the planning of these banquets ..2 MEDICAL ALUMNI BULLETIN_mtam 1lBtWtp 1lBabts1913·1944Only recently we have learned that Wil­liam Dewey Davis, class of '38-'39, waskilled, August 1944, in New Guinea. Inreply to a communication requesting furtherinjormation, Mrs.. Davis sent a leller fromwhich we are quoting with her permission,H' c feel that 110 bellcr memorial could beioriiten than the tribute contained in thefollowing lines."Shortly after Pearl Harbor, Deweyvolunteered his services and was called inMay, 1942. He was assigned to the 44thDiv. at Fort Lewis, Washington, andserved with the 44th until November,1943. In late November he went overseasto the South Pacific, where he was as­signed to the arst Div. as rst Bn. Sur­geon. A few months later he was sent ondetached service to the 112th Cavalry.He served in New Britain and New Gui­nea with the 112th Cavalry, and it was inNew Guinea that he met his death inAugust, 1944."It is a colorless and commonplacestory, yet if you knew Dewey you wouldknow that in his quiet unassuming wayhe was the epitome of good soldiering andsincere and heartfelt medicine. He askedfor combat duty because he felt that noone else could do his part for him, yet hespoke in his letters of how helpless he feltwhen the infantry went into combat andhe was relatively safe behind them-they W. DEWEY DAVIStook so much and he so little. If what Ihave heard is true, Dewey was giving aidto wounded men when he was struck. Itis terribly lonely without him, and histwo small children shall miss his compan­ionship and love. But there can be nobitterness for any of us because we knowhe was where he wanted most to be­doing his part side by side with his men.No one can ask more. He is our inspira­tion, and in my humble way I am tryingto continue our contribution to the defeatof fascism."Dr. Hansen DiesMilton B. Hansen, M.D., Moline, Illi­nois, died April IS at Moline Public Hos­pital of cerebral hemorrhage. Dr. Hansenreceived his M.D. at the School of Medi­cine, University of Chicago, with the classof 1935. He began practice in Moline in1939, was in charge of the medical de­partment of the Formall works since 1940,and was a past president of the staff ofMoline Public Hospital.Dr. Hansen was born September 12,1904, in Moline. He attended MolineHigh School and _ Augustana Collegebefore entering the University of Chicagofor his medical work. He married LoisRita Fennell of Davenport on June 27,1944. Surviving are the widow, his moth­er, Mrs. William Cook of Moline, and abrother, Dr. Clarence W. Hansen of Chi­cago.Capt. Sasko MissingThe following is from a letter of April 8from Mrs. Helen Sasko, Cincinnati, Ohio,concerning her husband Captain Vladi­mir Sasko, M.D. '38:"My husband has been missing sinceDecember 10, 1944 in the Pacific area. Ihave had very few details ..... I remainhopeful that he is safe and will returneventually." fi,trbJart �(!'tbrDavid B. Stewart was killed in actionon Iwo Jima. He attended the Universityof Chicago, where he was a premedicalstudent. He also was an orderly in theoperating-rooms of Billings Hospital._David was in the Navy for two years andhad been attached to the Marine Corpssince March of 1944.Pfc. John Blythe, former Billings Hos­pital admitting officer, was killed in Ger­many on February 8. He had been in serv­ice since June 17, 1943, and had servedoverseas for a year as forward observerwith the field artillery. He had beenawarded two Purple Hearts with a cita­tion for bravery. Jap Internment CampDr. Frank Whitacre, former U. of C.faculty member, who was a prisoner of warin Manila and returned to the United Stateson -the "Gripsholm;" has been full-time as­sociate professor of obstetrics and gynecol­ogy at the University of Tennessee, Mem­phis, since January I. Dr. Whitacre gradu­ated [rom the College of Medicine, Univer­sity of Iowa, in 1926 and was formerly aprofessor of obstetrics and gynecology atPeiping Union Medical College, Peking,China. He kindly consented to relate his.experiences in the Santo Tomas internmentcamp.By Frank E. Whitacre, M.D.I enjoyed a most interesting and prof­itable experience in obstetrics and gyne­cology from 1939 to 1941 inclusive, atwhich time I was working in the PeipingUnion Medical College of Peking, China.The first indication that this happyepisode would come to a conclusion wasa request by the State Department to theeffect that women and children should goback to the United States. Thus, Mrs.Whitacre and the two little boys leftPeking in November, 1940. I left Pekingin November, 1941, and arrived in Manilaon December 2, expecting to proceed. farther within a few days. Some of thefollowing material is taken from a pre­vious article (JAM A, 124: 652-53, 1944).On the day of the first bombing in thePhilippines some of us worked in theSternberg Army Hospital as civilianvoluntary assistants and continued to doso until the retreat to Bataan. The menin my ward were those who had been in­jured when the Japanese attacked ourbombers at Clark Field. Many of the menseriously injured were transferred the lat­ter part of December to Australia on ahospital ship. By that time the fall of(Continued on page 3)SCHOOL OF MEDICINEVOL. 1 JULY 1945 No.3F. B. GORDO", EditorHUBERTA LIVINGSTONE, Associate EditorALLAN T. KENYON, A ssociate Editor(Scientific Section)HENRY T. RICKETTS, Associate EditorW,LLIAM B. TUCKER, CLAYTON G. LOOSLIAssistant EditorsH. P. JENKINS, Business ManagerMRS. ROSEMARY JANDA, Reporter forResident StaffSTANLEY H. MOULTON, Reporter for Senior ClassBRUCE HEINZEN, Reporter for Junior ClassDELBERT M. BERGENSTAL, Reporter for.Sophomore ClossMELVIN M. NEWMAN, PhotographerJACK KABOUN, Assistant PhotographerPrice' of yearly subscription for nonmembers, $1.00;price of single copies, 25 cents.MEDICAL ALUMNI BULLETIN 3Internment Camp-(Continued from page 2)Manila was imminent, and we gatheredtogether in various sized groups to awaitthe entrance of the Japanese army, whichoccurred on January 2, 1942. The SantoTomas internment camp was opened andoperating by January 5. This university isthe oldest under American protection andcomprises about fifty acres and thirteenbuildings. We were allowed to use morethan half of the space-both as to build­ings and grounds. This provided onlyabout 30 square feet of floor space perperson. No beds or other necessities werefurnished by the Japanese.The American ability for organizationwas soon apparent. The Japanese, whowere not bothered with details, allowedthe people to look after their own internalmanagement as long as it did not conflictwith their ideas. An executive committeewas formed, and the. chairman was di­rectly responsible to the Japanese com- 'manding officer. Subcommittees werecreated to administer finance and supply,order and safety, sanitation and hygiene,work assignment, construction, kitchens,medical attention, education, and recrea­tion. Religious activities were not neglect­ed, and, in fact, all the functions requiredby a community of this size were providedfor.For a few months we obtained sup­plies from the Red Cross, but these weresoon exhausted, and on July I, 1942, theJapanese government began to supplyfunds for the support of the camp. Thiswas at the rate of 35 cents per person perday. This allowance must cover all ex­penses of the camp including food, sup­plies, water, and electricity. The construc­tion and operation of kitchens to providethe meager allowance of food for 3,900people was remarkable in its quick efficien­cy. For the first two years people were per­mitted to obtain one cooked meal a dayfrom the outside, and this was sent inpackages which were carefully inspected.During the first two years, two RedCross gift packages were given to eachperson+one from Johannesburg, SouthAfrica, and the other from Toronto,Canada. At ,the time that I left SantoTomas we were allowed a diet of 1,800calories per day containing SO grams ofprotein and 30 grams of fat; about"half ofthe latter was obtained from animalsources. As would be expected, losses ofweight from thirty to fifty pounds werecommon, and borderline cases of avita­minosis were observed.During the time of my internment theJapanese attitude was chiefly indiffer­ence. The close confinement and lack ofadequate food were, however, a constantmenace and were beginning to show far­reaching consequences. About a thousandsick and elderly persons were allowed toleave camp if they could show that theycould be self-supporting and. had a placeto stay, but in May, 19.43, at the timePremier Tojo visited Manila, all these people were brought back to camp. Thebuildings had, in the meantime, becomeovercrowded from the reception of smallgroups who were brought in from theprovinces; and to make room for the re­turning sick and elderly, about 800 of theyounger men were compelled to go to acamp about 40 miles away. The camphospital did very well in taking care ofthe sick, considering the lack of drugs andsupplies. At first we had 80 beds, and thiswas later increased to 120. The nursingsituation was adequate. For a time wehad a few civilian internee nurses aidedby the Philippine Red Cross. Later theMary Knoll Sisters came in to help us,and finally the Army and the Navynurses who had been taken at Bataan andCorregidor were interned at Santo Tomasand did a splendid job in taking care ofour hospital.We found the Filipinos to be bothbrave' and dependable. In the early daysof internment they were often our mainsource of supply for drugs, medical equip­ment, and even food, The Philippine Gen­eral Hospital reserved a ward of SO bedsfor men and one of 12 beds for women,and the Filipino doctors did an enormousamount of medical and surgical work withno thought of compensation.The first serious epidemic occurredsoon after internment when a wave of en­teritis swept the camp. This was followedby amebic dysentery. Dengue fever final­ly caught up with the newcomers, andthis was followed by an epidemic of about1 So cases of catarrhal jaundice. We sawmany persons afflicted with malaria, butapparently no new cases could be tracedto the city of Manila. Anterior poliomye­litis had involved about 12 persons and alike number with severe herpes zoster atthe time that I left.The 300 children were well cared for,as milk supplies and other foods were re­served for them, and we arranged for aseparate hospital of IS beds to take careof such childhood diseases as should arise.The expected childhood diseases wouldbe the same as here except for scarletfever, which, is very rare in the Philip­pines. As early as November, 1943, vita­min deficiencies were in evidence. Thenumber of deaths after the first 22 monthswas not in excess of what would be ex­pected for a like group in normal times,but the gradual depletion of the reserve,particularly of the internees, made it clearthat the mortality must increase. Drugsfor treatment of dysentery, the supply ofinsulin and liver extract, sulfonamidedrugs, narcotics, and anesthesias werepractically exhausted. Someof these werereplaced by the supplies which were sentout on the "Gripsholm" at the time thatthis historic ship brought us home in De­cember, 1943.Shortly after we left Santo Tomasthere was a radical change in the treat­ment by the Japanese. The previous Jap­.anese civilian administration was takenover by the Japanese army. Restrictionswere much more severe, and the diet was reduced to less than 700 calories per dayper person. I have talked with some of thepeople who were in our camp hospitaland who were recently released whenGeneral MacArthur's forces took, thecamp. Many of those about whom I in­quired are dead. Some were killed byshelling when the Japanese turned theirartillery on the civilian camp. Manymore died in the last three months fromjust plain starvation, and some of thecamp leaders who had done the most fortheir fellow-men in trouble were executed.It is obVIOUS to me that I missed the worstof this. It is also obvious from the waythe civilians were treated and from muchother evidence the kind of enemy thatour forces are fighting in the Pacific.WHITACRE BORKINLETTER FROM BaRKINCaptain Eli L. Borkin is with the Al­lied Military Government in Europe. Thefollowing, which might be called "On the. Road to Berlin," is taken from a letter re­ceived by his wife several months ago.Mrs. Borkin is employed at Billings Hos­pital.It is 9:30 P.M. candlelight time and herewe are moved again. To come here we trav­eled all day yesterday and when we arrivedwe found a huge castle which a few hours agowas inhabited by the Germans. Their souve­nirs are everywhere--and more. We foundtwo Teller mines in the room we're using as'a mess. The grounds are loaded with minesand German ammunition. There are mortarshells, helmets, a kind of bazooka gun, ma­chine gun bullets and all kinds of souvenirs ofthe recent battle. There's a lovely gray horsein the grounds--dead and smelly. Tanks andtrucks smashed lying about line the road.German clothes and dead are in evidence. Wegot here quite late in the day and it was rain­ing--coming I think we must have passed thewhole Polish army.Once arrived we had to unload our trucksand get the house and grounds cleaned up as,well as cook a meal. I had the dispensary setup in an old studio with a whole roof of glass--beautifully light. In addition my room isnext to the hospital--which has been bombed17 times. It's a lovely old room and it's a treatjust to be under a roof. There's even a closetin my room. The whole place has but one"cabinete," and it has to be flushed with apail of water each time. This evening I had'to call on a patient--a tiny dying infant with(Continued on page 9)4 MEDICAL ALUMNI BULLETINSCIENTIFIC SECTIONAn introduction to the work of the Uni­versity on the problem of malaria was pro­vided in our last issue by Dr.IHuff's sum­mary. This theme is further developed byDr. E. A. Evans, Jr., chairman of the De­partment of Biochemistry, discussing hisstudies on the metabolism of a malarialparasite. Dr. William E. Adams, of theDepartment of Surgery and an alumnus ofof the resident staff, has clarified the ques­tion of the safety of massive blood transfu­sions in his review of the work of his group.Dr. William Burrows, Department ofBacteriology and Parasitology, has sum­marized some of his recent investigations onthe cholera vibria. Dr. George F. Dick hasgenerously given us reprints of his impor­tant recent work on experimental hyper­tension to accompany this issue.Biochemistry of an AvianMalaria ParasiteThe erythrocytic form of P. gallinace­um affords a convenient experimentalsystem for the study of the metabolismof the blood stages in the development ofthe malaria parasite.Technics have been devised for ob­taining washed suspensions of parasiticchicken erythrocytes and of estimatingthe active parasitic mass present in suchsuspensions. It is possible to show thatsuch suspensions oxidize glucose with theintermediate formation of lactic and py­ruvic acids. Some 20 or 30 per cent of the, glucose used by the organisms cannot, asyet, be accounted for, although such pos­sibilities as the conversion of this missingglucose into fat, cholesterol, etc., havebeen explored.Under anaerobic conditions the or­ganism retains its infectivity providedsufficient quantities of glucose are pres­ent. Under these circumstances the glu­cose used can be accounted for quantita­tively as lactic acid. The study of cell­free extracts of the parasite has demon­strated that the mechanism of formationof lactic acid from glucose by the parasiteproceeds by a mechanism similar to, oridentical with, the phosphorylating gly­colysis that occurs in mammalian muscleand other tissues.Simultaneously with the aerobic utili­zation of glucose by the plasmodium thereoccurs an intensive breakdown of intra­cellular protein (hemoglobin) to give largeincreases in amino nitrogen. This prote­olytic breakdown is apparently coupledwith the aerobic utilization of glucose,since it is inhibited by anaerobiosis oragents tending to inhibit the oxygen up­take of the organism. It has also beenpossible to prepare cell-free extracts fromthe parasite capable of the hydrolysisof hemoglobin. The complete oxidation of lactic andpyruvic acids to carbon dioxide and water'by the parasite is catalyzed by smallamounts of fumaric acid and is inhibitedby malonic acid. It seems probable, there­fore, that the oxidative removal of a por­tion of pyruvic acid by the parasite fol­lows a mechanism similar to the tricar­boxylic acid cycle of carbohydrate oxida­tion in mammalian muscle.Studies have been made of the effectof atabrine and quinine on the variousenzymes of the systems discussed above.A concentration of 0.001 M quinine in­hibits the over-all process of lactate for­mation from glucose by enzyme extractsfrom the parasite as well as the enzymeshexokinase and lactic dehydrogenasewhich are part of the glycolytic mechan­ism. However, it seems improbable thatsufficient concentrations to cause theseeffects are obtained in vivo. With "physi­ological" concentrations of quinine theprincipal effect seems to be on the mech­anism of pyruvate oxidation. It should bepossible, therefore, to localize the effectof the drug on the enzyme system of theparasite if complete information aboutthe mechanism of pyruvate oxidation be­comes available,E. A. EVANS, JR.Blood Transfusions, The value of blood transfusions in im­proving and widening the scope of sur­gery and in saving battle casualties fol­lowing severe blood loss has become moreand more appreciated. The amount ofblood lost in extensive major operationsof the chest and abdomen has frequentlybeen grossly underestimated. Actual de­terminations revealed that 1500 cc: ofblood is an average los's for lobectomy,pneumonectomy, and extensive abdomi­nal and . thoraco-abdorninal operations(I). In some instances the loss was asmuch as 3,000 cc. Accordingly, an at­tempt has been made in this hospital toreplace blood while it is being lost with anequal amount of whole blood or plasma,chiefly the former.Recently, on the basis of animal ex­perimentation, a warning was issuedagainst the too liberal use of citratedblood. Ivy and his co-workers (2) bleddogs from 45 to 60 per cent of their esti­mated blood volume within a period of 3to 20 minutes. If no replacement of thisloss was made, 84 per cent of the dogsdied; when the loss was rapidly replacedby citrated whole blood or plasma over as-minute period, 50 and 70 per cent of thedogs, respectively, died. They postulatedthat if 1500 cC.-2500 cc. of citrated bloodwere given rather rapidly to a 70-kg. manafter a severe hemorrhage, it might proveto be fatally toxic. Bruneau and Graham (3) reported ex­periments in which dogs were bled 10 percent of the estimated blood volume andthe blood then reinjected during a i-hourperiod. The reinjected blood containedeither 0.6 per cent sodium citrate or hep­arin. The hemorrhages were repeateduntil the animals died. The dogs receivingthe citrated blood expired after an aver­age of 9.25 hemorrhages, or approximate­ly 92.5 per cent of the estimated bloodvolume; while the dogs receiving hepa­rinized blood survived 25.2 hemorrhages,or 252 per cent of their blood volume be­fore death. The authors believed thatsome factor other than sodium citratecontributed to the deleterious effects.However, they, too, warned against theexcessive use of citrate in large transfu­sions.Massive whole blood and/or plasmatransfusions were given to 53 patients onseveral Surgical Services at the Univer­sity of Chicago' Clinics (4) during 35abdominal, 16 thoracic, and 2 extremityoperations. The volume of blood and/orplasma administered was 1,500-3,000 cc.in 40 patients and 3,000-7,000 cc. in theremainder. The rate of administrationwas 1,500-2,500 cc. over periods of 2-6hours in most patients. Sodium citrate,2.5 gm. for each 500 cc. of whole blood,and 4.0 gm. for 500 cc. of plasma wasroutinely employed. According to bloodstudies made before and following opera­tion, no one was overtransfused and thegood postoperative condition of thesepatients re-emphasized the importance ofreplacement of blood. Transfusion reac­tions were not observed.In order to clarify the discrepancy be­tween our clinical experience and theviews of Ivy and his co-workers gainedfrom animal investigation, experimentswere made on 65 dogs to examine theharmful effects of massive transfusions ofcitra ted whole blood (5).The following conclusions may bedrawn: 'I. Massive transfusion of citratedwhole blood for the treatment of extremeshock (blood pressure of 30-45 rom. Hg.)produced by hemorrhage of as much as 60per cent of the estimated blood volumewere safely tolerated in dogs when thereplacement of blood loss was made dur-',ing a period of 20 minu tes or longer.2. When bleeding and transfusionswere conducted simultaneously, an aver­age of I I 2 per cent of the estimated bloodvolume was exchanged during a period of70 minutes before the animal expired.This would correspond to a transfusionof 7,840 cc. of blood given during thesame period of time for a 70-kg. man.When the rate of bleeding and trans-(Continued on page 7)MEDICAL ALUMNI BULLETIN 5Mice," Proc. Soc. Exper. Bioi. &- Med.,56: 166, 1944·---. "Studies on the Action of Penicillin.III. Bactericidal Action of Penicillin onMeningococcus in vitro," ibid., 56: 205,1944·Palmer, Walter L. "Errors in the Diagnosisof Neoplastic Lesions of the Rectum, Rec­tosigmoid and Colon," Medical Clinics ojNorth America (Chicago Number), pp.278-86, January, 1944 (withJ. B. Kirsner).Richter, Richard. "Observations Bearing onthe Presence of Latent Herpes SimplexVirus irf the Human Gasserian Ganglion,"J. Nerv. and Ment. Dis., 99:356,1944.Ricketts, Henry T. "The Effect in Man ofChronic Intermittent Anoxia on GlucoseTolerance and the Urinary Excretion ofSodium, Potassium, Chloride, Phosphorus,Nitrogen, and 17-Ketosteroids," J. Clin.Endocrinol., 4:450, 1944 (with A. HughesBryan).Robertson, O. H. "A Study of the Natureand Control of Air-borne Infections inArmy Camps," JAMA, 126:993, 1944(with M. Hamburger, C. C. Loosli, T. T.Puck, H. M. Lemon, and H. Wise).Rothman, Stephen. "The Physiology of theSkin," Ann. Rev. Physiol., 4: 195-224,1944 (with Peter Flesch).Tucker, William B. "Tuberculosis Control inGeneral Hospitals," Hospitals, November,1944 (with Robert G. Bloch and Arthur C.Bachmeyer).Obstetrics and GynecologyDieckmann, William J. "Calcium, Phos­phorus, Iron and Nitrogen Balances in(Continued on page 6)MedicineEichelberger, Lillian. "Water, Nitrogen andElectrolyte Concentration in Brain,"J. Bioi. Chem., 154: 2I, 1944 (with Rich­ard B. Richter).---. "Studies on Tumors of the Testis. I.Water and Electrolyte Content of Testicu­lar Tumors and of Normal Cryptorchidand Estrogenized Testis," Cancer Re­search, 4:447, 1944 (with Charles Hug­gins).Eisele, C. Wesley. "The Distribution ofWater, Nitrogen and Electrolytes inSkin," J. Bioi. Chem., 151:177; 1943.Gomori, George. "The Effect of ParenterallyAdministered Citrate on the Renal Excre­tion of Calcium," Proc. Soc. Exp. Biol. &­Med., 56:226, 1944 (with E. Gulyas).Gray, S. J. "The Use of Fibrinogen in a RapidMethod of Determining Cell Volume."Amer. J. Med. Sci., 207: 29-39, 1944.Kenyon, Allan T. "Anabolic Affects of theAndrogens and Somatic Growth in Man,' ,Ann. Int. Med., 20 :632,1944 (with Knowl­ton and Sandiford).Masserman, Jules H. "The Psychodyna­misms of Propaganda and Morale," Dis.Neru. Syst., 5: 101-II, 1944.Miller, C. Phillip. "A Survey of ChronicMeningococcus Carriers in a Semiperma­nent Population, J. Infect. Dis., 74: 212,1944·---. "Studies on the Action of Penicillin.I. The Rapidity of Its Therapeutic Effecton Gonococcic Urethritis," J AM A, 125:607, 1944·---. "Studies on the Action of Penicillin.II. Therapeutic Action of Penicillin onExperimental Meningococcal Infection inFaculty PublicationsTo acquaint the Alumni with the investi­gations that are going on in the departmentsof the Medical School, we have asked thefaculty to submit lists of their publicationswhich appeared during the past year. Thefirst of these are presented here.rAnatomyBensley, Sylvia H. "Cytological Studies ofthe Reaction of Myelinated Nerve Fibersto Section of the Nerve," Anat. Rec., 90:I-IS, 1944.Bacteriology and ParasitologyGordon, F. B. "Immunologic Relations of thePsittacosis-Lymphogranuloma Group ofViral Agents," Proc. Soc. Exper. Bioi. &­Med., 56: 159-61, 1944 (with M. R. Hille­man).Huff, Clay G. "Second Report of the Com­mittee on Terminology of Strains of AvianMalaria," J. Parasit., 30: 206-8, 1900(with Frederick Coulstori).Koser, Stewart A. "A Study of the para­Aminobenzoic Acid Requirement of Clos­tridium acetobutylicum: Application to As­say Procedure," J. Infec, Dis., 75: II3, 1944(with R. D. Housewright).Taliaferro, W. H. "The Effect of Immunityon the Asexual Reproduction of Plasmo­dium brasilianum," J. Infec. Dis .. , 75: 1-32,1944·BiochemistryEvans, E. A., Jr. "The Fixation of CO, byAnimal Tissue" (Harvey Lecture), 39:273, 1944·Sponsored by theCOMMITTEE ON BIOLOGY AND MEDICINEX-RAY EXAMINATION OF THE STOMACH.By Frederick E. Templeton, M.D ..An intensive study of the upper digestive tract, includingthe newest X-ray technics used in gastro-intestinal ex­aminations."A delightful type of book by a man who evidently isinterested in trying to find out the why's of things .....The many illustrations are beautiful."-WALTER C.ALVAREZ, Mayo Clinic. $10.00 VASCULAR RESPONSES IN THE EXTREMI ..TIES OF MAN IN HEALTH AND DISEASE.By David I. Abramson, M.D."Methods and clinical applications are thoroughly dealtwith, and anatomic, physiologic and pharmacologic in­formation is interpreted in its relation to disease."­Archives oj Internal Medicine. $5.00BEHAVIOR AND NEUROSIS. By Jules H.Masserman, M.D."The book is probably as significant a contribution to anexperimental verification of psychoanalytic concepts ashas thus far been produced."- Journal oj the AmericanMedical Association. $3.00FOOD POISONING. By G. M. Dack, M.D."This book for which there is currently a brisk need, pre­sents a critical evaluation of the agents responsible forfood poisoning and food-borne infections. The author'sanalysis is fortified by an extensive personal experience inthe field of experimental investigation of many aspects ofthe subject."-Military Surgeon. $2.00 Watch for the forthcomingCARBOHYDRATE METABOLISM. By SamuelSoskin, M.D., and Rachmiel LevineA MANUAL OF MEDICAL PARASITOLOGY.By Clay 6 HuffIncludes an unusually valuable five-color plate of malari­al parasites. 11 zincs. $1.50 UNIVERSITY OF CHICA6P PRESS6 MEDICAL ALUMNI BULLETIN55· WILLIAM C. MCBRIDE, JR., M.D., assist.resident, Chicago Lying-in Hosp.,'32-'33, recently in private practice,Ob. & Gyn., Portland, Ore., now cap­tain, M.C., at the Letterman GeneralHosp., Dante Annex, San Francisco.EDWARD B. KINPORTS, M.D. '42, of In­ternational Falls, Minn., recently in­tern at Illinois Central Hosp., nowcaptain, M.C., in medical clearing;company in Pacific area. ,.J. EDWARD BRYANT, M.D., research as-'sistant (vol.), assistant (vol.), Dept.Med., '38-'41, now on staff, ProvidentHosp., Chicago.KENNETH McLANE SMITH, M.D. '37, re­cently of University Hosp., Ann Ar­bor, Mich., '37-'41, now lieutenantcolonel, M.C., chief of medical serviceof station hospital (overseas),PAUL PIERCE PICKERING, M.D., Rush'41, D.D.S. (Univ. of Tenn. '34), as­sistant in Zoller Dental Clinic, '36-'39,now lieutenant commander, M.C.,U.S.N., assigned to a fleet hospital inPacific area.FRANCIS J. PHILLIPS, M.D., Rush '37,fellowship in surgery, '38-'39, nowmajor, M.C., with artillery division,APO,N.Y.LEONARD A. STINE, M.D. '40, M.S.(Path.) '39, recently intern, assist.res. at Michael Reese Hosp., Chicago,now captain, M.C., in an evacuationhospital overseas.ALBERT TELFEYAN SARKIS, M.D. '42, of3035 89th St., Jackson Hts., N.Y., re­centlyinternat New York City Hosp.,Welfare . Island, now captain, M.C.,battalion surgeon in Engineer Regi­ment, APO, N.Y.LLEWELYN P. HOWELL, M.D. '31, res.staff, med., '30-'31, fellowship, MayoFoundation, '31-'36, now on staff ofMayo Clinic and instructor, MayoFoundation.JOHN HAROLD EDGECOMB, class of 1946,B.S. '44, 714 Chapel St., Ottawa, Ill.ANDREW J. BRISLEN, M.D. '36, intern,'35-'36, assist. Dept. Med. '37-'41,now major, M.C., at the A.A.F. R. &C. Hosp. Unit B., Coral Gables 34,Fla.CORNELIUS A. HOSPERS, M.D. '32, in­tern, surg. '34-'35, assist. Dept. Path.'29-'32, recently pathologist, Engle­wood, So. Chicago, and Holy CrossHosp., now lieutenant colonel, M.C.,in Medical Lab. unit, APO, N.Y.HENRY T. RICKETTS, M.D., res. staff,med. '31-'33, instr., assist. prof., '33-'43, now assoc. prof. Dept. Medicine.CHARLES R. MOWREY, JR., M.D. '43, re­cently intern at New Haven Hosp.,now lieutenant (j.g.), M.C., U.S.N.R.,on duty in Pacific area (includingvisits to Guam and Iwo Jima).FREDERICK WILLIAM FRANK, M.D., re­cently intern, assist. res., CincinnatiGen. Hosp., now senior resident, psy­chiatry, Dept. Medicine.OMAR JOHN FAREED, M.D. '40, res. staff,Med. '40-'41, now instr. Dept. Medi­cine.JAMES McILROY FRITZ, M.D. '42, res.staff, surg. '42-'43, now lieutenant,M.C., U.S.N.R., with a Marine divi­sion in the Pacific.FRED L. ADAIR, M.D. Rush '01, MaryCampau Ryerson Prof. Emeritus,Obs. & Gyn., Chesterton, Ind.(Continued on page 7)Faculty Publications­(Continued from page 5)Pregnant Women," Amer. J. Obst. &'Gynec., 47:357, 1944·Hesseltine, H. Close. "Report of the Com­mittee on the Health of Women in Indus­try," West. J. Surg., 52:372, 1944.Potter, Edith L. The Rh Factor in Obstet­rics," Medical Clinics of North America,28: 254, 1944.Willson, J. Robert. "Treatment of BenignUterine Bleeding in the Menopause," Ill.MJ., 85:295-98,1944.PediatricsAdams, Wright. "Common Forms of Con­genital Heart Disease," Med. Clinics ofNorth America, 28:95, 1944 (with D. E.Cassels).VanderVeer, Adrian H. "Clinical Applicationof the Thematic Apperception Test toNeurotic Children," Amer. J. Orthopsy­ckiat., 14:421-40, 1944 (with Eva R.Balken).PharmacologyGeiling, E. M. K. "The Preparation andProperties of a Metabolic Derivative ofQuinine," J. Pharm, &' Exp, Therapeutics,80 :391-92, 1944.PhysiologyCarlson, A. J. "The Conditioned ReflexTherapy of Alcohol Addiction," Quart. J.Studies on Alcohol, 5: 2I2, 1944.Luckhardt, Arno B. "William Harvey,"Quarterly Bulletin Northwestern Univ.M ed. School, 18: 141-45, 1944.SurgeryAdams, William E. "The Use of Plasma forFilling the Pleural Space after Loss ofVarying Amounts of Lung," Surgery,15:521-46, 1944 (with T. F. Thornton.jr.).Brunschwig, Alexander. "Intravenous Ad­ministration of Fat for Nutritional Pur­poses, Experimental Study, Arch. Surg.,48:395-405, 1944 (with Lucia Dunham).---. "Alloxan in the Treatment of InsulinProducing Islet Cell Carcinoma of thePancreas," JAMA, 124:124-40, 1944(with 1- Garrott Allen, Frederick M.Owens, Jr. and T. F. Thornton, Jr.).Dragstedt, L. R. "Supra-Diaphragmatic Sec­tion of the Vagus Nerves in the Treatmentof Duodenal and Gastric Ulcers," Gastro­enteral, 3 :450-61, 1944 (with Walter L.Palmer, Paul W. Schafer, and Paul C.Hodges).Krause, A. C. "Treatnient of MetastaticMeningococcic Endophthalmitis. Reportof a Case," Arch. Ophth., 32: 109-12,1944(with William Rosenberg).Lindsay, J. R. L. "Meniere's Disease: His­topathologic Observations," Arch. Oto­laryng., 39:313-18,1944.Livingstone, H. "Mediastinal and Subcutane­- ous Emphysema Following IntratrachealInsufflation Anesthesia," A nesth, &' A nalg.,23: 177-88, 1944.Perlman, H. B. "Vitamins in Otolaryngol­ogy," Ann. Otol. Rhinol, &' Laryng., 53:267-74, 1944·Phemister, D. B. "Shock in Extremity Sur­gery," J. Bone and Joint Surgery, 26:197,1944·Walker, A. E. "The Physiological Basis ofConcussion," J. Neurosurg., I: 103-16,1944 (with Case and Kollros).Zoller FoundationWassermann, F. "Analysis of Formation ofDental Enamel in Normal and Vitamin C Deficient Guinea Pigs," J. Dent. Research,December, 1944.MiscellaneousBachmeyer, A. C. "The Hospital in ModernSociety" (with Gerhard Hartman) ed. I,Commonwealth Fund, 1943.Whitecotton, G. Otis. "Budgetary Controlfor Hospitals," published in concentratedform in Modern Hospital, 62: 63-65, 1944,under title, "Presenting the Budget, aPlan for the Future."LIFE-MEMBERSHIPS40. JERRY STYRT, graduating class of June'45, B.S. '40, internship, U. of C.Clinics.ULYSSES G. MASON, JR., M.D. '36, re­cently intern, assist. res., resident atCleveland City Hosp., '36-'39, nowon staff. 'SARAH AURORA PEARL, M.D., assistant,'35-'38, Dept. Ob. & Gyn., ChicagoLying-in Hosp., now in private prac­tice, Ob. & Gyn., 409 N. CamdenDrive, Beverly Hills, Calif.RUTH HERRICK, M.D. Rush '28, res.staff, instr., Dept. Med. (Derm.) '28-'31. Now in private practice, derma­tology, Grand Rapids, Mich.PAUL E. Ross, M.D. '37, recently assist.prof., pathology, Univ. of Arkansas,now attending pathologist, Method­ist Hosp., Gary, Ind., and Silver CrossHosp., Joliet, III.JAMES C. P,. FEARINGTON, M.D. Rush'29, res. staff, Med., '30-'31, now onstaff of Baptist Hosp. and CityMemorial Hosp., Winston-Salem,N.C.LEON BELASCO COMROE, M.D. '37, ofChicago, now captain, M.C., in chargeof a convertible hospital unit in Euro­pean theater.ARTHUR LOEWY, M.D. '43, recently in­tern at Michael Reese Hosp., Chica­go, assist. res. at St. Francis Hosp.,Evanston, now lieutenant, M.C., atLa Garde Gen. Hosp., New Orleans,La.RICHARD K. CURRIER, M.D. '42, of Elm­wood, Ill., now captain, M.C., inportable surgical hospital "somewherein the Philippines."FRANCIS L. ROOK, M.D. '42, of Kenmore,N.Y., recently intern at HuntingtonMem. Hosp., Pasadena, now lieu­tenant, U.S.N.R.JOHN POST, M.D. '37, res. staff, surg.,'37-'38, recently staff of Presbyterianand Chi. Memorial Hosp., now lieu­tenant colonel, M.C., in the Pacificarea.JEROME A. GANS, M.D., res. staff, '39-'41, instructor, ophth., on leave forservice in Army, now captain, M.C.,in general hospital overseas.GLENWAY W. NETHER CUT, M.D. Rush'26, res. staff, ophth., '27-'28, now at­tending ophthalmologist, ChicagoMem. Hosp. and Illinois Eye and EarInfirmary of Univ. of Illinois Med.School.SAMUEL S. BLANKSTEIN, M.D. Rush '34,res. staff, ophth. '36-'38, now onstaff, ophthalmologist, Mount SinaiHosp. and Milwaukee Children'sHosp.CRAWFORD J. CAMPBELL, M.D., res. staff,surgery, and orthopedics' 40-' 42, nowcaptain, M.C., in general hospital inPhilippine area.41.42.43·44·45·47·49·50.51.52.53·54· 56.57·58.59·60.62.66.68.70.71.72•MEDICAL ALUMNI BULLETIN 7Transfusions-«(f;ontinued from page 4)usion was less rapid, a larger volume was.xchanged without reaction.Thus, a large margin of safety is pres­.nt even in massive transfusions of citrat­.d whole blood' or plasma when the ad­ninistration is at a maximum rate cur­rently employed in man (1,000 cc. per.our).3. Calcium gluconate was very effec­ive in preventing or alleviating citratentoxication when very large doses of.itrate had been administered during ahort period of time. Bleeding and simul­.aneous transfusion of citrated wholeslood to the extent of 200 per cent of the-stimated blood volume, during a periodIf 2 hours, were well tolerated when ade­[uate amounts of calcium gluconate wereised.W. E. ADAMS:. White, M. L., and Buxton, R. W. BloodLoss in Thoracic Operations. J.. Thor.Surg., 12: 198-202, 1942. .:. Ivy, A. C.; Greengard, H.; Stein, J. F., Jr.;Grodius, F. S.; and Dutton, D. F. TheEffect of Various Blood Substitutes in Re­suscitation after an Otherwise FatalHemorrhage. Surg., Gynec. &t Obst., '76:85-90, 1943·\. Bruneau, J:tcques, and Graham, Evarts A.A Caution against Too Liberal Use ofCitrated Blood in Transfusions. Arch.Surg., 47: 319, 1943·�. Allen, J. Garrott; Clark, Dwight E.;Thornton, Thomas F., Jr.; and Adams,W. E. The Transfusion of Massive Vol­umes of Citra ted Whole Blood and Plasmain Man: Clinical Evidence of Its Safety.Surgery, IS: 824-31, 1944.;. Adams, W. E.; Thornton, T. F., Jr.; Al­len,]. Garrott; and Gonzalez, D. E. TheDanger and Prevention of Citrate Intoxi­cation in Massive Transfusions of WholeBlood. Ann. Surg., 120:656, 1944.CholeraAs yet .it is not altogether clearvhether or not an effective prophylacticrnmunity can be produced against bac­terial invasion when the infection occursoutside the tissues proper. Diphtheria,oacillary dysentery, and Asiatic choleraare such diseases; the causative micro­rrganisms establish infection withoutoenetration of the. cellular organization)f the host and consequently are not ex­oosed to the action of circulating anti­body or phagocytic cells until the diseasehas developed. In the first of these aneffective immunity may be produced,but it is an antitoxic immunity, prevent­ing the manifestations of the toxemia butnot infection of the mucous membranes)f the upper respiratory tract by thebacilli. In the enteric infections of thistype, a reasonably effective prophylacticimmunity is very difficult to produce, andit is felt by many that such an immunityhas not yet been produced. It is perhapssignificant that the immune response, asassayed by the passive protection test innice, appears to be associated with anti- body to the heat stable cell substancewhich, in the case of dysentery bacilli,has been found to be closely associated ifnot identical with the endotoxin.In Asiatic cholera the clinical evi­dences of infection suggest a toxemia. Inthe opinion of many the clinical syndromeand histopathology can be accounted foran the basis of profound dehydration andhypochloremia and subsequent alkalosisand impairment of renal function, and itis not necessary to assume that there isabsorption of the cholera endotoxin fromthe lumen of the bowel as it is liberatedby disintegration of the vibrios. From thispoint of view, the action of the toxin isessentially local; desquamation of theepithelium is well known, and presum­ably the mucosa is affected in some man­ner to give rise to the purging diarrhea.In the course of studies on immunityto cholera carried out for the Committeeon Medical Research of the Office ofScientific Research and Development thecholera endotoxin has been isolated andpurified, and its properties have beenfound to be of considerable interest in re­lation to the disease in man. It has beenshown that it is dialyzable, extractable'from the boiled vibrios with trichloraceticacid and some organic solvents includingethyl alcohol, chloroform, and ethyl etherbut not by glycols, is resistant to proteo­lytic digestion, and appears to be closelyassociated with phospholipid. In view ofthe low molecular weight, it is of particu­lar interest that the activity has beenfound to be antigenic, even though thebarrier of dialysis is interposed betweenthe intact vibrio and the immunizingpreparation. The antibody response hasbeen manifested as protective antibody,in both actively and passively immunizedanimals, against mucin-vibrios, but it hasnot been possible to protect against thetoxicity of purified preparations.The purified endotoxin has been shownto increase markedly the permeability ofliving membranes, frog skin and guineapig and rabbit small intestine, to fluids.The rate of flow resulting from a hydro­static pressure of 6-8 inches is approxi­mately doubled in the presence of purifiedendotoxin in concentrations of approxi­mately four mouse MLD's per ml. ofRinger-Locke solution. The acceleratingaction is not neutralized in the presenceof hyperimmune anticholera serum, butintestine taken from the immune animaland washed in Ringer-Locke solution iscompletely resistant to the action of thetoxin. The resistance is clearly an immunereaction and, since it cannot be attribut­ed to the action of circulating antibody,functional antibody must be presentwithin the tissue, very possibly in the cellsof the lymphoid-macrophage system.These observations suggest that aneffective prophylactic immunity to chol­era may be an antitoxic immunity, mani­fested as a local immunity of the intesti­nal tract. The possibility is presentedthat it might be attained through the useof detoxified endotoxin preparations or vaccines fortified with such preparationsas immunizing agents. This work has beenreported in preliminary form in three pa­pers in the Proceedings of the Society forExperimental Biology and Medicine, 57:306,308, and 311,1944.WILLIAM BURROWSALUMNI SENATEA quarterly dinner meeting of the Sen-. ate was held in the Quadrangle Club,Wednesday, May 16, with Dr. VictorJohnson presiding. Dr. Prohaska gave acomplete report on the financial statussince reorganization.Dr. Wright Adams, chairman of theMembership Committee, presented forapproval by the Senate a list of member­ship applicants who were made membersby unanimous approval. Dr. F. B. Gor­don, editor of the BULLETIN, reported onthe status of that publication. Dean F. J.Mullin, our representative on the faculty,reported on the activities of the Commit­tee on Internships.Dr. William Tucker gave a report on aproblem he has ably and enthusiasticallytackled. It is the old problem of the Chi­cago Medical School alumnus: "To whichclass do I belong?" With the assistanceof Miss Wentworth, he has prepared acomplete listing of graduates of this medi­cal school, and suggested a method ofgrouping them according to classes. Be­tween 1929 and 1936, 170 degrees ofBachelor of Medicine were awarded, withthe M.D. degree being awarded followinga year or more of either research or in­ternship. Dr. Tucker suggested that thedate of completion of the four-year Medi­cal School program be considered theyear of graduation for the purposes of ourAlumni Association and also that theclasses be grouped by the calendar year.When two classes graduate in one year,they shall be recorded as individualclasses and designated by the month aswell as the year. Students of irregular at­tendance are to be assigned to a class ar­bitrarily by Dr. Tucker, with their con­sent when obtainable. The English orother foreign students who have fulfilledrequirements for a degree are to be con­sidered as alumni. These suggestions fromDr. Tucker's report were all approved bythe Senate. The corrected list with ad­dresses is to be published in the 1945Senior Year Book.Life-M emberships­(Continued from page 6)73. HAROLD C. HOUSTON, M.D. '32, res.staff, med., path., roentgenology, '33-'38, now radiologist, Luther Hosp.,Eau Claire, Wis.74. JOSEPH L. JOHNSON, M.D. '31, Ph.D. '31,professor and chairman, Dept. Physi­ology, Howard University, School ofMedicine. Washington. D.C.8 MEDICAL ALUMNI BULLETINl'ox .mebicorumOne of the functions of the BULLETIN isto serve as a medium for the presentation ofideas concerning our medical school and itsproblems by the members of the Associationor others interested. We will be glad to re­ceive letters for ·publication in this.column.Please remember that our space is limited.The two great challenges to the futureof American medicine are (1) adequatedistribution of medical care, both geo­graphically and economically, and (2)improved quality of medical care. Thelatter will be accomplished by the pro­mulgation of group practice. In this ourmedical school should become a leader,because of the outstanding example ofgroup practice daily set before its stu­dents in the form of its full-time clinicstaff. It is to be hoped that the Curricu­lum Committee will more fully utilizethis in courses emphasizing the impli­cations of group practice as a part of thedevelopment of a sense of social re­sponsibility so lacking in the average phy­sician. It is only in retrospect that manyof us appreciate the contact we had witha group of men who assumed responsi­bilities toward the patient only in so faras they were trained for the task at hand,freely admitting the need for co-operationwith someone of another specialty. Thisis in marked contrast to the bulk of pres­ent medical practice, more often becauseof inadequate specialized personnel avail­able, but also because of a lack in develop­ment of a sense of medical co-operationwhen such personnel is available. An en­lightened society is demanding certainthings of the medical profession. Weshould prepare our students to meet thesedemands.VERNON R. DEYOUNG, M.D. '321945 YEARBOOKThe Alumni Association is pleased tosponsor the distribution of this secondYearbook, the proceeds from which willgo to the 1945 Class Endowment Fundof the Association.The 1945 Yearbook fulfils many func­tions, and many were the whistles of en­thusiasm and gasps of astonishment onits appearance early in June. It serves asa pictorial handbook for the highly pho- .togenic campus, with its introductorysection of campus views. It serves as acatalog for the more or less photogenicmembers of the Class of 1945. 'The Facul­ty and Resident Staff are as completelyrepresented as possible, together withquiet lampoons of their services. Theunderclassmen and organizations are allpictured, as are most of the nurses.The Yearbook also serves as a directoryfor all graduates of the University of Chi­cago School of Medicine and for all mem­bers of the Alumni Association, as well asfor all life-members to date. THE FACULTYMore than half of our alumni graduatedbefore 1939, and therefore probablydo notknow many of the faculty members ap­pointed since that date. These are the secondof a' series of introductions to our newerfaculty members.Dr. J. Robert Willson, who is assistantprofessor of obstetrics and gynecology,has been on the staff of the clinics since'1942. He came to us from the Universityof Michigan, where he obtained his un­dergraduate degree, his Master's degreein obstetrics and gynecology, and wherehe had practiced and taught his specialtyfor five years. Dr. Willson was born inFlint, Michigan. His published papers in­clude studies on uterine and ovarian tu­mors, benign uterine bleeding, surgery ofthe ovary, erythroblastosis fetalis, thepharmacologic action of veratrone and re­lated drugs, and others. His special in­terests are the toxemias of pregnancy andgynecologic cancer. Dr. Willson's hobbyis photography. He is married and thefather of two children.Dr. Peter P. H. De Bruyn, assistantWILLSON DEBRUYNprofessor of anatomy, was born in Am­sterdam, Holland. He received his M.D.in 1938 from the University of Amster­dam and in 1939 worked for a three­month period in the Department of Anat­omy at the University of Chicago underthe Stokvis Fund.Dr. De Bruyn was a first lieutenant inthe medical corps of the Dutch army untilJune, 1940, and was a prisoner of war fora short period after the Germans overranHolland. In March, 1941, he was appoint­ed as an instructor in anatomy at the Uni­versity of Chicago. His studies have beenespecially concerned with the amoeboidmotion of blood cells.Dr. De Bruyn is married and has twodaughters aged eleven and seven years.In the last BULLETIN we published astatement, obtained from reliable sources,that Captain Joseph B. Kirsner had beenawarded the Bronze Star. Word has justbeen received that Captain ·Kirsner hasnot received a decoration. We deeply re­gret the error. A number of our faculty members are onleave for military service and we are repre­sented also by many former faculty membersnow in service. Some of these men have beenmentioned previously in these columns; wepresent others below.Charles L. Spurr, instructor in theDepartment of Medicine, is on leave fd:'service in the Medical Corps, U.S.N.R_.He has been assigned to duty on the medi !, cal service of the U.S. Naval Hospital;Great Lakes, Ill. Dr. Spurr came to theUniversity of Chicago in 1940 from theUniversity of Rochester as an intern inthe Department of Medicine. He was as­sistant resident and resident in 1941 and,after a short appointment as assistant,was appointed instructor in 1942. He hasbeen in charge of the employees' healthservice and the Hematology Clinic. Heenlisted in the Medical Corps of theNavy on March 19, 1945.Lt. Col. Henry W. Brosin, assistantprofessor of psychiatry, Department ofMedicine, is on leave for military service.He is chief consultant in psychiatry ofSPURR MOOREthe Third Service Command, Baltimore 2, Md.On leave of absence since March 51945, is Lt. (j.g.) Robert D. Moore. Aftebeing temporarily stationed at GreatLakes Naval Training Station, in throrthopedic section, he was sent to LODIIsland, where his unit is organizing fooverseas duty. He will be in charge 0orthopedics in this unit. Lt. Moore earn.to the University .Clinics in 1939 after getting his A.B. at the University of California in 1935 and his M.D. at the University of Rochester School of Medicine iJ1939. He was on the Surgical ResidenStaff from 1939 to 1944 and was an instructor in orthopedic surgery. Lt. Mooris a diplomate of the ,American Board cOrthopedic Surgery and a member of thAmerican Orthopaedic Association. He jmarried and has two children.Lt. Francis P. Guida, M.C., instructcin ophthalmology from July, 1937, tjuly, 1939, is now stationed at GreaLakes, after having been in the Carilbean and Pacific areas.(Continued on page 9)MEDICAL ALUMNI BULLETIN 9Paculty-(Continued from page 8)Lt. Martin Goldner, assistant profes­.• or of medicine (on leave), is located at:he Regional Hosp., Fort McClellan, Ala.He has been particularly interested innetabolic diseases, and his work on dia­�etes produced by alloxan, in colla bora­·.ion with Dr. Gomori, was reviewed in theast issue of the BULLETIN.On April 20 Dr. A. Earl Walker be­came a major in the Medical Corps of theJnited States Army. He received hisM.D. degree from the University of Al­oerta and came to the University of Chi­:ago Clinics as a Douglas Smith Fellow.n 1931. The following year he was resi­Ient on neurology and in 1934 was resi­Ient on neurosurgery.Major Walker was at the University of[owa from 1934 to 1935. During 1935-37ne was a Rockefeller Fellow, spendingtime at Yale University, the University)f Amsterdam's Neurologische Kliniek,and the Laboratoire de Pathologie Gene­rale of the Universite Libre de Bruxelles.In 1937 Dr. Walker returned to theUniversity of Chicago to be an instructorin neurology and neuropathologist. Since194� he has been associate professor ofGOLDNER WALKERsurgery and chief of the NeurosurgicalService.Major Walker has been certified by theAmerican Board of Psychiatry and Neu­rology and by the American Board ofNeurological Surgery and is a Fellow ofthe American College of Surgeons.Lt. Col. Harwell Wilson received anM.D. from Vanderbilt University and in1932 was a surgical intern at the Univer­sity of Chicago Clinics. Following this in­ternship, he remained on the surgical resi­dent stat! and from July I, 1938, to JulyI, 1939, was instructor in surgery andchief surgical resident. Before enteringthe Army, he was on the. faculty of theUniversity of Tennessee at Memphis.Dr. Wilson has been overseas nearlytwo years and has had varied experience.His last assignment was with an evacua­tion hospital unit, where he "found thework more spectacular and at times moredangerous than previous jobs. I have usu­ally been in the operating tent twelvehours straight, either all night or all day,with rounds before and after. The workhas been varied and major. Repairing stomachs, removing spleens, repairing di­aphragms, etc. with sterile gloves but nogowns left sterile gives an idea of the rush.With good surgeons, good anesthesia, andall the whole blood we need, it is remark­able what can be done in a tent."Lt. Seymour Gray, U.S.N.R., assist­ant professor of medicine, on leave, willsoon be stationed at Bethesda, Md.Dr. Gray received his M.D. from theUniversity of Pennsylvania in 1936. From1937 to 194 I he was resident in the De­partment of Medicine at the Universityof Chicago. In July, 1941, he became in­structor in medicine and was advanced toassistant professor in July, 1944. Dr.Gray became a diplomate of the Ameri­can Board of Internal Medicine in 1944and in March, 1945, received a ·:ph.D. inmedicine at the University of Chicago.He has been particularly trained in gas­troenterology and has been associatedwith both Dr. Rudolf Schindler and Dr.Walter Palmer. Lt. Gray is married andhas two children.Lt. Alfred Klein, assistant in medicine,1939-41, and instructor in medicine,1941-42, has left for an assignment to anaval air station on the island of Oahu,near Honolulu. His former ship, the"Helena," a light cruiser sunk in KulaWILSON GRAYGulf in July, 1943, has been honored byhaving all men aboard her in that actionawarded the Presidential Unit Citation.Lt. Klein has been at Northwestern Uni­versity, assigned to the dispensary at thenaval unit there. .Borkin-(Continued from page 3)jaundice, and we were taken in a two-wheelcart and a horse, for there was no transport.... really the 'country doctor,' eh? Amstarting early in the morning to do a job ofpatching wounded coming out of caves in arecently liberated town. Yesterday, since theenemy was all about looking over our place,it was impossible to get to them so I wentthrough a hospital where 200 patients werehuddled in a basement. We're doing what wecan to restore the place and get it ready to re­ceive the wounded coming back from anothertown. So it goes-smash, clean it up, andmove forward.Last night, in addition to unpacking,cleaning, and caring for the wounded, we eachtook two hours' guard duty, since we weretold Germans were in the neighborhood. Yep,packed a gun! Across the Dinner TableThe resident staff is a part of the medicalschool organization that one tends to takefor granted, in spite of the significance of itscontribution to our general effort. It wasproposed to remedy this situation by askingMrs. Rosemary Janda, wife of Dr. RudolphJanda, assistant resident, to present themembers of the present resident staff. Thesecond instalment follows.Just as all family circles decrease asthe tides of war beckon, our group is real­ly being broken up come the first of July.We hate to see our fellows leave, but weknow that a finer bunch couldn't befound and that they will make us proudwhether it be aboard a battleship or on abattle front.The Army's appetite seems to bestronger, inasmuch as it's calling a great­er number of men into service. Sheddingtheir white for khaki are Bob Bigelow,Mike Bonfiglio, and Herbert Johnson.Ralph Victor will miss the Carlisle exo­dus, since his first three months will bespent at the Mason General Hospital re­viewing some of the problems of neuro­psychiatry, before heading for the Penn­sylvania plains.We'll have to watch for Tom Thorntonin the footnotes of Yank rather than inthe Journal of the A.M.A. in the future.Tom was having a well-merited vacationas we went to press and couldn't bereached for further information, but weknow the Navy will be well satisfied withhis work. Hope the two respective Medi­cal Corps realize they're getting a superresident stat! at one blow!Instead of the familiar call from Tele­page, Paul Woolf is another who will behearing the words and music to "AnchorsAweigh." Paul won't have to worry toomuch about the family situation as he'sleaving a dandy little boy to look out forhis wife.We mentioned in an earlier issue thatDonald MacDonald will be among theHorn Pipers. And Jim Frey rather thinksthat he'll be singing the Navy Blues, al­though he still has an iron in the fire atthe Henry Ford Hospital in Detroit.Mel Newman has been planning to gointo the Army once the rigorous life of in­terning was over. And John Newland willhit the dusty trail after coming the longway, Carlisle via Santa Barbara, Buffalo,. and Chicago.Arnold Axelrod received a reprieve inthe form of a letter extending his stay foran additional three months, or on orabout the first of October. In the mean­time, he's going to divide his time be­tween Health Service and Cardiology.Walter Arons leaves us in July, but fora different type of service. Originally fromthe Quaker City, Walt will head backeast to Boston, where he will be asso­ciated with the Shields Warren Labora­tory of Pathology.There's not much we can say but bonvoyage and good luck, fellows. We'll missyou all.10 MEDICAL ALUMNI BULLETINALUMNI NEWS'32. Maj. Alven M. Weil, res. staff, '31-'33,recently in private practice, Ob. & Gyn.(cert. by Amer. Bd.), 573 Moreley Ave.,Akron, Ohio, is now assigned to the hospitalship "Thistle."'34. Hance F. Heaney is professor of physi­ology and clinical instructor in medicine,University of Oregon Medical School, 2450S.W. Sherwood Drive, Portland I, Ore.'35. Wallace Byrd is in practice (internalmedicine) at the Rugeley-Blasingame Clinic,Wharton, Texas ..... V. Brown Scott, Ph.D.'34 (Dept. Physiol.) recently assistant pro­fessor of physiology, Indiana Univ. School ofMed., is now in practice (internal medicine)at Inlow Clinic, Shelbyville, Ind.'36. John E. Moseley is assistant radiolo­gist, Mount Sinai Hosp., and associate radi­ologist at Sydenham Hosp., besides being aninstructor in radiology at Columbia Univ.'37. A note received from Kenneth Smithinforms us of his promotion to lieutenantcolonel. .... Rulon F. Howe of Murray,Utah, recently" fellow in surgery, MayoFoundation, is now Lt. Col., M.C., in theheadquarters of the Second Air Force, Officeof the Surgeon ..... Maj. M. David Burn­stine, in the Pacific theater, writes as follows:"Odell, of the class of '38 is out here too, anda captain in the Marines. A good guy and wesee each other often. Plenty of work here andin our hospital chiefly Major Surgical. I'mC.O., and chief surg., and anxious to gethome."'38. Merton Max Gill has been at the Men­ninger Clinic, Topeka, Kan., where he is nowon the staff in neuropsychiatry ..... Char­lotte G. Babcock, res. staff, '39-'41, instructorin psychiatry, '41-'44, is now in private prac­tice, 8 S. Michigan Ave., Chicago.'39. A note recently received from Maj.Laurence S. Jennings (Tenth Air Disarma­ment Group, Ninth AFSC, APO 639, NewYork) states: "Am now surgeon for an airdisarmament group whose function is appar­ent from the title. We take the Lujt out of theLuftwaffe-interesting but one becomes verybooby-trap conscious. Just spent two weeksD.S. at a hospital in England and ran intoCapt. John Hammer and Capt. Julius Fried(M.D. '40), both on duty there. Many of thepatients were POW's from von Runstedt'sbreak-through. Also there as chief of the med­ical service was Lt. Col. Kenneth Smith(M.D. '37). We had a swell school reunion.Hope our next reunion is at Hanley's! Mildand Bitter is all right, but, oh you, Schlitz!Incidentally I gave Hammer a shellacking atdarts-let him deny it if he dares!" ....John B. Rowe of Milford, Mich., recentlyinterned at Univ. of Iowa Hosp. and assistant :resident at Hurley Hosp., Flint, Mich., is nowa lieutenant commander in the Marines, as­signed to a headquarters squadron somewherein the Pacific. I'40. Lt. Philip J. Clark, Marine flight sur­geon, writes Dr. Phemister of eighteen inter­esting and active months of service at PearlHarbor, Saipan, Guam, the Marshalls, and,now, Okinawa. He recently sent samples ofoccupational currency in yen and sen to thesecretary of the Association.'42. Capt. Isadore Rossman, Ph.D. '37, isin England, where he has been since early1944, after interning 1942-43 at Los AngelesCounty Hosp., then at Carlisle Barracks,then a brief period in Alabama. His present work is mostly with casualties evacuatedfrom the western front, and in particular hehad a great many cases of "immersion foot"following the Ardennes offensive ..... Capt.Harvey Blank of 1653 E. Fifty-fifth St., Chi­cago, recently intern at Harper Hosp., De­troit, is now in a general hospital, APO, NewYork ..... Capt. Marvin S. Freilich, of 3100Sheridan Road, Chicago 14, recently internat Michael Reese Hosp., is now in the medicaldetachment of military police battalion, APO,San Francisco ..... Lieut. Edward R. Wood­ward, of 9 Oak Drive, Mason City, Iowa, re­cently intern in the department of surgery, isnow assigned to LSD ..... Catherine Arm­strong (Seward), '42, res. staff, medicine, '42-, 43, recently at Childrens Memorial Hosp.,and Contagious Disease Hosp., Chicago, isnow at Children's Medical Center, Dallas 4,Texas.'43. Stanford K. Sweany, recently intern,U.S. Naval Hosp., Great Lakes, is now as­signed to sea duty in the Pacific area .....Capt. Chas. P. McCartney has seen ac­tive service in northern Italy. At times he hasbeen glad that the Italians built their houseswith thick walls. The Italian civilians whomhe treats occasionally present him with eggs,wine, or goat's butter. The latter he "buriedafter dark so as not to offend anyone, since,from the smell of it, burial seemed appropri­ate." .... Lt. Harold R. Reames, Ph.D. '40,of Grand Ledge, Mich., is now located atFrederick, Md ..... Lt. Arthur M. Gray re­cently intern, Jackson Mem Hosp., Miami,Fla., is assigned to a Marine division whichhas recently seen "considerable" action .....Capt. Byron L. Casey of 404 Vine Ave., ParkRidge, III., recently intern at Illinois CentralHosp., Chicago, is now assigned to a medicalbattalion, APO, New York ..... Lt. (j.g.)W. H. T. Murray is attached to the Twenty­eighth Regiment, Fifth Marine Division­the regiment that raised the flag on MountSuribachi. He was landed on Iwo Jima andwas on Iwo for six weeks or so and is nowback at his base camp. He says that he had alovely beard, that Iwo was a filthy hole, andthat he has worked pretty hard ..... JayBartlett expects to stay on as a senior residentin surgery at Billings Hosp ..... AI D'Ales­sandro is a resident surgeon at Brooklyn'sKing's County Hosp ..... Robert McCor­mack is a resident surgeon at the Univ. ofRochester Strong Memorial Hosp ..... Lt. Y.Thomas Oester is now at Percy Jones Gen­eral Hosp., Battle Creek, Mich., doing neuro­surgical work ..... Lt. Franz W. Wasser­mann left for overseas duty with a psychiatricunitin January, a few days after his marriage..... When last heard from Lts. (j.g.) R. LeonSmith, Clifton York, and Ted Mafit were onthe West Coast expecting Pacific sea dutysoon ..... Chester B. Powell has residencyin neurology and neurosurgery at IllinoisNeuropsychiatric Institute ..... Walter Bed­ford Cox has a fellowship in radiology at Ma­yo Clinic ... : . William Wicks expects to re­main as senior resident in anesthesiology atBillings Hosp.'44. William A. Hall is now at Boston CityHosp. and expects to enter active service inthe Navy on the completion of his nine­month internship. Six-week intervals havebeen spent, in turn, on medicine, surgicalOPD, neurosurgery, and G-U. Is now back ona general surgical service, the third. RECENT VISITORSLt. Herbert D. Trace, '42, on furloughafter two years of service with the M4rines, was a recent clinics visitor. He wa]with the Fourth Marine Division at Saijpan, Tinian, and Iwo Jima. Lt. Trace re]ceived the Bronze Star for his service onthe Saipan beachhead, and also wears aPresidential Unit Citation with Starwhich was awarded his division for serv­ice at Saipan and Tinian. He reports thathe met two classmates, Lts. Donald M.McIntyre and A. R. Furmanski, in Hono­lulu recently.Edmund Walsh, '3$, res. staff., med.& derm. '36-'40, has been in the Armysince June, 1942. He has recently been ona thirty-day leave from the 'Gorgas Hosp.in Panama, where he is in charge of theV-D clinic. Major Walsh spent severaldays in Chicago seeing old friends.WALSH MITCHELLRESIDENT STAFFEarl B. Mitchell, formerly assistant, Dept.Medicine and associated with Dr. Bloch inthe Chest Clinic and Hosp. service, is now acaptain with a general hospital located nearBrisbane. He has been overseas for a year anda half ..... Lucien A. Gregg, int., assist.res., res., and assistant, dept. med. 136-'39,recently in private practice {internal medi­cine) (cert. by Amer. Bd.), and on facultyofthe Univ. of Pittsburgh, is now a lieutenantcolonel in an Army general hospital inEngland ..... Jerome T. Jerome, res. staff(ornith. surg.), '31-'34, is in private practicein Traverse City, Mich., doing orthopedicsurgery (cert. by Amer. Bd.) ..... Paul E.McMaster, M.D., Rush '29, res. staff, sur­gery, orth. '30--'33, faculty of Univ. of South­ern California since 1933, is now a comman­der in the Marines in charge of the orthopedicservice of the U.S. Naval Hosp., Long Beach,Calif. He has been in the Navy since 1941 andhas had twenty-three months of service in theSouth Pacific area during the "busy season.'Lt. John Batty, former assistant resident irmedicine, has had a year each on a destroye:and at Pearl Harbor. He was wearing battlestars for Palau and the Marshall Islands. LtBatty is now stationed at the Univ. of Dubuque, where there is a V-I2 program.